Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Shailaja Akunuru"'
Autor:
Ming Liu, Zheng Zhang, Leesa Sampson, Xuan Zhou, Kodandaramireddy Nalapareddy, Yuxin Feng, Shailaja Akunuru, Jaime Melendez, Ashley Kuenzi Davis, Feng Bi, Hartmut Geiger, Mei Xin, Yi Zheng
Publikováno v:
Stem Cell Reports, Vol 9, Iss 6, Pp 1961-1975 (2017)
Summary: RHOA, a founding member of the Rho GTPase family, is critical for actomyosin dynamics, polarity, and morphogenesis in response to developmental cues, mechanical stress, and inflammation. In murine small intestinal epithelium, inducible RHOA
Externí odkaz:
https://doaj.org/article/1153bd8c5202450e98fe432b2de8460f
Autor:
Karine Z. Oben, Subbarao Bondada, Ahmed Abdel-Latif, Sunil K. Noothi, Sara S. Alhakeem, Ramesh C. Gupta, Natarajan Muthusamy, Jason A. Brandon, Liu Jinpeng, Daret K. St. Clair, Sanjit K. Dhar, Harold F. Stills, Kaoru Tohyama, Rajeswaran Mani, Chi Wang, Shailaja Akunuru, Mary K. McKenna, Ying Liang, Hartmut Geiger, Inder Pal Singh
Publikováno v:
Oncotarget
// Karine Z. Oben 1 , Sara S. Alhakeem 1 , Mary K. McKenna 1 , Jason A. Brandon 2 , Rajeswaran Mani 3 , Sunil K. Noothi 1 , Liu Jinpeng 4 , Shailaja Akunuru 5 , Sanjit K. Dhar 6 , Inder P. Singh 7 , Ying Liang 6 , Chi Wang 4 , Ahmed Abdel-Latif 2 , H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64ca32055a1a62ef78e46a2bb370eb18
http://europepmc.org/articles/PMC5652791
http://europepmc.org/articles/PMC5652791
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e16951 (2011)
The cancer stem cell (CSC) theory predicts that a small fraction of cancer cells possess unique self-renewal activity and mediate tumor initiation and propagation. However, the molecular mechanisms involved in CSC regulation remains unclear, impingin
Externí odkaz:
https://doaj.org/article/870ef69a2cbb446b98f788c9e2470db1
Autor:
Yi Zheng, Ashley Kuenzi Davis, Yuxin Feng, Kodandaramireddy Nalapareddy, Xuan Zhou, Leesa Sampson, Feng Bi, Zheng Zhang, Hartmut Geiger, Ming Liu, Shailaja Akunuru, Jaime Melendez, Mei Xin
Publikováno v:
Stem Cell Reports
Stem Cell Reports, Vol 9, Iss 6, Pp 1961-1975 (2017)
Stem Cell Reports, Vol 9, Iss 6, Pp 1961-1975 (2017)
Summary RHOA, a founding member of the Rho GTPase family, is critical for actomyosin dynamics, polarity, and morphogenesis in response to developmental cues, mechanical stress, and inflammation. In murine small intestinal epithelium, inducible RHOA d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d3e8506783faa145a5451b1f6f1e1d0
https://doi.org/10.1016/j.stemcr.2017.10.004
https://doi.org/10.1016/j.stemcr.2017.10.004
Autor:
Marie Dominique Filippi, Hartmut Geiger, Yi Zheng, Daniel T. Starczynowski, Matthew T. Weirauch, Susanne Christie, Xiaona Liu, Kenneth D. Greis, Lyndsey Bolanos, Shailaja Akunuru, Kwangmin Choi, Jing Fang, Jaroslaw P. Maciejewski, Guillermo Garcia-Manero, Peter Stoilov, Nathan Salomonis, Dehua Wang, Xiaoting Chen, Rupali Kumar
Publikováno v:
Nature immunology
Toll-like receptor (TLR) activation contributes to premalignant hematologic conditions, such as myelodysplastic syndromes (MDS). TRAF6, a TLR effector with ubiquitin (Ub) ligase activity, is overexpressed in MDS hematopoietic stem/progenitor cells (H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6016df55d2c1a46bd5b02347f678220f
http://europepmc.org/articles/PMC5423405
http://europepmc.org/articles/PMC5423405
Autor:
Shailaja Akunuru, Hartmut Geiger
Publikováno v:
Trends in Molecular Medicine. 22:701-712
Aging is associated with reduced organ function and increased disease incidence. Hematopoietic stem cell (HSC) aging driven by both cell intrinsic and extrinsic factors is linked to impaired HSC self-renewal and regeneration, aging-associated immune
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8080132979aa37cb07a3de0f52613101
https://doi.org/10.1016/j.molmed.2016.06.003
https://doi.org/10.1016/j.molmed.2016.06.003
Autor:
Dehua Wang, Daniel T. Starczynowski, Nathan Salamonis, Xiaoting Chen, Kenneth D. Greis, Guillermo Garcia-Manero, Hartmut Geiger, Lyndsey Bolanos, Yi Zheng, Kwangmin Choi, Rupali Sani Kumar, Marie-Dominique Filippi, Xiaona Liu, Shailaja Akunuru, Jing Fang, Peter Stoilov, Matthew T. Weirauch, Susanne Christie, Jaroslaw P. Maciejewski
Nat. Immunol. 18, 236–245; published online 26 December 2016; corrected after print 23 January 2017 In the version of this article initially published online, the 16th author's surname was spelled incorrectly as 'Salamonis'. The correct spelling is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db2fc2aac45fc700d1e31b6375708f3d
https://europepmc.org/articles/PMC5505686/
https://europepmc.org/articles/PMC5505686/
Autor:
Yi Zheng, Shailaja Akunuru, Jaime Melendez, Ming Liu, Leesa Sampson, David P. Witte, Jefferson E. Vallance, Noah F. Shroyer, Xiaonan Han
Publikováno v:
Gastroenterology. 145:808-819
Background & Aims Cdc42 is a Rho GTPase that regulates diverse cellular functions, including proliferation, differentiation, migration, and polarity. In the intestinal epithelium, a balance among these events maintains homeostasis. We used genetic te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7342e073fd5a3ce634eccad6dff9be9c
https://doi.org/10.1053/j.gastro.2013.06.021
https://doi.org/10.1053/j.gastro.2013.06.021
Autor:
Matthew Kofron, Susanne I. Wells, Richard J. Morreale, Monique A. Morrison, Shailaja Akunuru, Yi Zheng
Publikováno v:
Journal of Virology. 85:10487-10498
Expression of the high-risk human papillomavirus (HPV) E6 and E7 oncogenes is essential for the initiation and maintenance of cervical cancer. The repression of both was previously shown to result in activation of their respective tumor suppressor ta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a55eb015ef9832a463eee1ede668b270
https://doi.org/10.1128/jvi.05126-11
https://doi.org/10.1128/jvi.05126-11
Autor:
Kenneth Walsh, Sujata Rao, Jefferson E. Vallance, Ivan B. Lobov, Laura E. Benjamin, Shailaja Akunuru, Richard A. Lang, Ichiro Shiojima, Kaoru Tsujikawa
Publikováno v:
Development. 134:4449-4458
Macrophages have a critical function in the recognition and engulfment of dead cells. In some settings, macrophages also actively signal programmed cell death. Here we show that during developmentally scheduled vascular regression,resident macrophage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5ab9ed65eed556dbcd51feb93a47781
https://doi.org/10.1242/dev.012187
https://doi.org/10.1242/dev.012187