Role of reactive oxygen species and sulfide-quinone oxoreductase in hydrogen sulfide-induced contraction of rat pulmonary arteries

Autor: Prieto-Lloret, Jesus, Snetkov, Vladimir, Shaifta, Yasin Mohammad, Docio, Inmaculada, Connolly, Michelle, MacKay, Charles Edward, Knock, Gregory Alan, Ward, Jeremy Patrick Thomas, Aaronson, Philip Irving

Publikováno v: Prieto-Lloret, J, Snetkov, V, Shaifta, Y M, Docio, I, Connolly, M, MacKay, C E, Knock, G A, Ward, J P T & Aaronson, P I 2018, ' Role of reactive oxygen species and sulfide-quinone oxoreductase in hydrogen sulfide-induced contraction of rat pulmonary arteries ', American Journal of Physiology-Lung Cellular and Molecular Physiology, vol. 314, no. 4, pp. L670-L685 . https://doi.org/10.1152/ajplung.00283.2016

Application of H2S (“sulfide”) elicits a complex contraction in rat pulmonary arteries (PAs) comprising a small transient contraction (phase 1; Ph1) followed by relaxation and then a second, larger, and more sustained contraction (phase 2; Ph2).

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https://kclpure.kcl.ac.uk/en/publications/1d9be899-af30-47fa-ae37-64929ee369ff