Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Shai-anne Nalder"'
Publikováno v:
eLife, Vol 9 (2020)
Doxycycline (DOX) is a key antimalarial drug thought to kill Plasmodium parasites by blocking protein translation in the essential apicoplast organelle. Clinical use is primarily limited to prophylaxis due to delayed second-cycle parasite death at 1
Externí odkaz:
https://doaj.org/article/c357fa8c47ce43b2acf3f9e12132fa51
Autor:
Tanya J. Espino-Sanchez, Henry Wienkers, Rebecca G. Marvin, Shai-anne Nalder, Aldo E. García-Guerrero, Peter E. VanNatta, Yasaman Jami-Alahmadi, Amanda Mixon Blackwell, Frank G. Whitby, James A. Wohlschlegel, Matthew T. Kieber-Emmons, Christopher P. Hill, Paul A. Sigala
Publikováno v:
Proceedings of the National Academy of Sciences. 120
The mitochondrial electron transport chain (ETC) of Plasmodium malaria parasites is a major antimalarial drug target, but critical cytochrome (cyt) functions remain unstudied and enigmatic. Parasites express two distinct cyt c homologs ( c and c -2)
Autor:
Tanya J. Espino-Sanchez, Henry Wienkers, Rebecca G. Marvin, Shai-anne Nalder, Aldo E. García-Guerrero, Peter E. VanNatta, Yasaman Jami-Alahmadi, Amanda Mixon Blackwell, Frank G. Whitby, James A. Wohlschlegel, Matthew T. Kieber-Emmons, Christopher P. Hill, Paul A. Sigala
Publikováno v:
bioRxiv
The mitochondrial electron transport chain (ETC) ofPlasmodiummalaria parasites is a major antimalarial drug target, but critical cytochrome functions remain unstudied and enigmatic. Parasites express two distinct cytchomologs (candc-2) with unusually
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3814302e47517bd5ef343f12627cd7f
https://europepmc.org/articles/PMC9900762/
https://europepmc.org/articles/PMC9900762/