Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Shai White‐Gilbertson"'
Autor:
Shai White-Gilbertson, Ping Lu, Ikechukwu Esobi, Jing Echesabal-Chen, Patrick J. Mulholland, Monika Gooz, Besim Ogretmen, Alexis Stamatikos, Christina Voelkel-Johnson
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Polyploid Giant Cancer Cells (PGCC) are increasingly being recognized as drivers of cancer recurrence. Therapy stress promotes the formation of these cells, which upon stress cessation often successfully generate more aggressive progeny that
Externí odkaz:
https://doaj.org/article/5d19c7a7507b474aa3ac89418fd4a9ad
Autor:
Robert R. Bowers, Maya F. Andrade, Christian M. Jones, Shai White-Gilbertson, Christina Voelkel-Johnson, Joe R. Delaney
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-13 (2022)
Abstract Background Genomic instability and chemoresistance can arise in cancer due to a unique form of plasticity: that of polyploid giant cancer cells (PGCCs). These cells form under the stress of chemotherapy and have higher than diploid chromosom
Externí odkaz:
https://doaj.org/article/54b64f90c5764688a4aa650cce72a63e
Autor:
Shai White‐Gilbertson, Ping Lu, Christian M. Jones, Stephanie Chiodini, Deborah Hurley, Arabinda Das, Joe R. Delaney, James S. Norris, Christina Voelkel‐Johnson
Publikováno v:
Cancer Medicine, Vol 9, Iss 9, Pp 3142-3152 (2020)
Abstract Polyploid giant cancer cells (PGCC) represent a poorly understood, small subpopulation of tumor cells that are increasingly being recognized for their critical role in therapy resistance, metastasis, and cancer recurrence. PGCC have the pote
Externí odkaz:
https://doaj.org/article/d1f6ae005b2e4bb4b8b54ea700442373
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 7, Pp 1225-1235 (2019)
Radiation treatment failure or relapse after initial response to chemotherapy presents significant clinical challenges in cancer patients. Escape from initial courses of treatment can involve reactivation of embryonic developmental stages, with the f
Externí odkaz:
https://doaj.org/article/27616cc3138c4feaa3a4322e7c69541f
Autor:
Ping Lu, Christina Voelkel-Johnson, Shai White-Gilbertson, James S. Norris, Stephanie Chiodini, Christian M. Jones, Arabinda Das, Joe R. Delaney, Deborah Hurley
Publikováno v:
Cancer Medicine, Vol 9, Iss 9, Pp 3142-3152 (2020)
Cancer Medicine
Cancer Medicine
Polyploid giant cancer cells (PGCC) represent a poorly understood, small subpopulation of tumor cells that are increasingly being recognized for their critical role in therapy resistance, metastasis, and cancer recurrence. PGCC have the potential to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52d91d98dcb9672de7607e37d4dfe81d
https://doaj.org/article/d1f6ae005b2e4bb4b8b54ea700442373
https://doaj.org/article/d1f6ae005b2e4bb4b8b54ea700442373
Autor:
Robert R. Bowers, Maya F. Andrade, Christian M. Jones, Shai White-Gilbertson, Christina Voelkel-Johnson, Joe R. Delaney
Publikováno v:
BMC cancer. 22(1)
Background Genomic instability and chemoresistance can arise in cancer due to a unique form of plasticity: that of polyploid giant cancer cells (PGCCs). These cells form under the stress of chemotherapy and have higher than diploid chromosome content
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5622ee031695c1c86820af40df8c52b1
https://pubmed.ncbi.nlm.nih.gov/35421971
https://pubmed.ncbi.nlm.nih.gov/35421971
Autor:
Janet E. Saunders, Peggi M. Angel, Anand Mehta, Shai White-Gilbertson, Elizabeth S. Yeh, Richard R. Drake, Christina Voelkel-Johnson, Cassandra L. Clift
Publikováno v:
Journal of Proteome Research. 18:3630-3639
Typically, N-glycosylation studies done on cultured cells require up to millions of cells followed by lengthy preparation to release, isolate, and profile N-glycans. To overcome these limitations, we report a rapid array-based workflow for profiling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ee8bdf2f8088e5ad1747c4f3932a612
https://doi.org/10.1021/acs.jproteome.9b00303
https://doi.org/10.1021/acs.jproteome.9b00303
Publikováno v:
Cancer Biology & Therapy. 20:922-930
Ceramide synthase 6 (CerS6) is an enzyme that preferentially generates pro-apoptotic C16-ceramide in the sphingolipid metabolic pathway. Reduced expression of CerS6 has been associated with apoptosis resistance and recent studies point to a role for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b9d593bcc4e39a0270d890bc0189727
https://doi.org/10.1080/15384047.2019.1579962
https://doi.org/10.1080/15384047.2019.1579962
Publikováno v:
Adv Cancer Res
Polyploid giant cancer cells (PGCC) constitute a dangerous subpopulation of cancer cells and are a driving force in cancer recurrence. These unique cells arise from diploid tumor cells in response to stress encountered in the tumor microenvironment o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b13c7dca3ea258b6ce9b2e9f57e4bcf
https://doi.org/10.1016/bs.acr.2020.03.001
https://doi.org/10.1016/bs.acr.2020.03.001
Autor:
Peggi M, Angel, Janet, Saunders, Cassandra L, Clift, Shai, White-Gilbertson, Christina, Voelkel-Johnson, Elizabeth, Yeh, Anand, Mehta, Richard R, Drake
Publikováno v:
J Proteome Res
Typically, N-glycosylation studies done on cultured cells require up to millions of cells followed by lengthy preparation to release, isolate, and profile N-glycans. To overcome these limitations, we report a rapid array-based workflow for profiling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::09faf315f0e051cb75bcbd316d71b15b
https://pubmed.ncbi.nlm.nih.gov/31535553
https://pubmed.ncbi.nlm.nih.gov/31535553