Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Shai Schlussel"'
Publikováno v:
Cell Reports, Vol 36, Iss 4, Pp 109428- (2021)
Summary: In an event reminiscent of eukaryotic ubiquitination, the bacterial prokaryotic ubiquitin-like protein (Pup)-proteasome system (PPS) marks target proteins for proteasomal degradation by covalently attaching Pup, the bacterial tagging molecul
Externí odkaz:
https://doaj.org/article/321aa819f64f48e6909f98642fd7f80f
Publikováno v:
Molecular Microbiology. 112:620-631
Despite being a destructive process, regulated protein degradation is fundamental for proper cell function. While regulated proteolysis in eukaryotes largely involves the ubiquitin-proteasome system (UPS), most bacterial species rely on multiple ATP-
Publikováno v:
Cell Reports, Vol 36, Iss 4, Pp 109428-(2021)
Summary In an event reminiscent of eukaryotic ubiquitination, the bacterial prokaryotic ubiquitin-like protein (Pup)-proteasome system (PPS) marks target proteins for proteasomal degradation by covalently attaching Pup, the bacterial tagging molecule
Publikováno v:
The FEBS Journal. 284:1804-1814
Pup, a ubiquitin analog, tags proteins for degradation by the bacterial proteasome. As an intracellular proteolytic system, the Pup-proteasome system (PPS) must be carefully regulated to prevent excessive protein degradation. Currently, those factors
Autor:
Yifat Elharar, Maayan Korman, Eyal Gur, Ofir Regev, Shai Schlussel, Nir Hecht, Nimrod Silberberg
Publikováno v:
Biochimica et biophysica acta. Molecular cell research. 1864(12)
Intracellular proteolysis is critical for the proper functioning of all cells, owing to its involvement in a wide range of processes. Because of the destructive nature of protein degradation, intracellular proteolysis is restricted by control mechani