Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Shai R. Joseph"'
Autor:
Elliott W Abrams, Ricardo Fuentes, Florence L Marlow, Manami Kobayashi, Hong Zhang, Sumei Lu, Lee Kapp, Shai R Joseph, Amy Kugath, Tripti Gupta, Virginia Lemon, Greg Runke, Amanda A Amodeo, Nadine L Vastenhouw, Mary C Mullins
Publikováno v:
PLoS Genetics, Vol 16, Iss 4, p e1008652 (2020)
Forward genetic screens remain at the forefront of biology as an unbiased approach for discovering and elucidating gene function at the organismal and molecular level. Past mutagenesis screens targeting maternal-effect genes identified a broad spectr
Externí odkaz:
https://doaj.org/article/5a7079db9b6942258bc6e78880fb3d19
Autor:
Shai R Joseph, Máté Pálfy, Lennart Hilbert, Mukesh Kumar, Jens Karschau, Vasily Zaburdaev, Andrej Shevchenko, Nadine L Vastenhouw
Publikováno v:
eLife, Vol 6 (2017)
Upon fertilization, the genome of animal embryos remains transcriptionally inactive until the maternal-to-zygotic transition. At this time, the embryo takes control of its development and transcription begins. How the onset of zygotic transcription i
Externí odkaz:
https://doaj.org/article/5c782853de664284869da6f83101720f
Publikováno v:
Current Opinion in Genetics & Development. 43:53-60
After fertilization, the embryonic genome is inactive until transcription is initiated during the maternal-to-zygotic transition. How the onset of transcription is regulated in a precisely timed manner, however, is a long standing question in biology
Autor:
Florence L. Marlow, Sumei Lu, Hong Zhang, Amanda A. Amodeo, Manami Kobayashi, Mary C. Mullins, Nadine L. Vastenhouw, Elliott W. Abrams, Shai R. Joseph, Virginia Lemon, Amy Kugath, Greg Runke, Tripti Gupta, Ricardo Fuentes, Lee Kapp
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 16, Iss 4, p e1008652 (2020)
PLoS Genetics, Vol 16, Iss 4, p e1008652 (2020)
Forward genetic screens remain at the forefront of biology as an unbiased approach for discovering and elucidating gene function at the organismal and molecular level. Past mutagenesis screens targeting maternal-effect genes identified a broad spectr
Autor:
Nadine L. Vastenhouw, Shai R. Joseph, Martina Augsburg, Marc Gentzel, Andrej Shevchenko, Frank Buchholz, Aliona Bogdanova, Mukesh Kumar, David N. Drechsel
Absolute quantification of proteins elucidates the molecular composition, regulation and dynamics of multiprotein assemblies and networks. Here we report on a method termed MS Western that accurately determines the molar abundance of dozens of user-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6edf88340b04427904229b6d5f6f403c
Autor:
Lennart Hilbert, Máté Pálfy, Shai R. Joseph, Andrej Shevchenko, Nadine L. Vastenhouw, Vasily Zaburdaev, Mukesh Kumar, Jens Karschau
Publikováno v:
eLife, Vol 6 (2017)
eLife
eLife
Upon fertilization, the genome of animal embryos remains transcriptionally inactive until the maternal-to-zygotic transition. At this time, the embryo takes control of its development and transcription begins. How the onset of zygotic transcription i
Autor:
Jeremy Troy Smith, Mark Jimenez, Kirsty A Walters, Reena Desai, Charles M. Allan, Shai R. Joseph, Guang Ning, Xiaobing B. Cheng, David J. Handelsman, Linda J. Middleton
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 305:E717-E726
Homozygous androgen receptor (AR)-knockout (ARKO) female mice are subfertile due to both intra- and extraovarian (neuroendocrine) defects as defined by ovary transplantation. Using ARKO mice, this study set out to reveal the precise AR-regulated path
Publikováno v:
Biophysical Journal. 112:152a
Autor:
Kirsty A Walters, Linda J. Middleton, David J. Handelsman, Shai R. Joseph, Charles M. Allan, Rasmani Hazra, Ulla Simanainen, Mark Jimenez
Publikováno v:
Biology of Reproduction. 87
Ovarian granulosa cells display strong androgen receptor (AR) expression, suggesting a functional role for direct AR-mediated actions within developing mammalian follicles. By crossing AR-floxed and anti-Mullerian hormone (AMH)-Cre recombinase mice,