Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Shahzma Merani"'
Autor:
Michaela Lucas, Pooja Deshpande, Ian James, Andri Rauch, Katja Pfafferott, Elouise Gaylard, Shahzma Merani, Anne Plauzolles, Andrew Lucas, Wyatt McDonnell, Spyros Kalams, Mark Pilkinton, Cody Chastain, Louise Barnett, Amy Prosser, Simon Mallal, Karen Fitzmaurice, Heidi Drummer, M. Azim Ansari, Vincent Pedergnana, Ellie Barnes, Mina John, Dermot Kelleher, Paul Klenerman, Silvana Gaudieri
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Abstract Hepatitis C virus (HCV)-specific T cell responses are critical for immune control of infection. Viral adaptation to these responses, via mutations within regions of the virus targeted by CD8+ T cells, is associated with viral persistence. Ho
Externí odkaz:
https://doaj.org/article/a3e921b0f5654281802b48dc72a509cb
Autor:
Arun Kumar, Janet E. McElhaney, Lisa Walrond, Terry D. Cyr, Shahzma Merani, Tobias R. Kollmann, Scott A. Halperin, David W. Scheifele
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 13, Iss 9, Pp 2048-2057 (2017)
Cellular immunity is important for protection against the serious complications of influenza in older adults. As it is unclear if newer influenza vaccines elicit greater cellular responses than standard vaccines, we compared responses to 2 standard a
Externí odkaz:
https://doaj.org/article/8a3fae832d714332a68ad9a78a3a1dc6
Impact of Aging and Cytomegalovirus on Immunological Response to Influenza Vaccination and Infection
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
The number of people over the age of 60 is expected to double by 2050 according to the WHO. This emphasizes the need to ensure optimized resilience to health stressors in late life. In older adults, influenza is one of the leading causes of catastrop
Externí odkaz:
https://doaj.org/article/7b43ee85e23a4e69b917f6cfcc3ace89
Autor:
Katja Pfafferott, Pooja Deshpande, Elizabeth McKinnon, Shahzma Merani, Andrew Lucas, David Heckerman, Simon Mallal, Mina John, Silvana Gaudieri, Michaela Lucas
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0130420 (2015)
Characterisation of Hepatitis C virus (HCV)-specific CD8+ T-cell responses in the context of multiple HCV exposures is critical to identify broadly protective immune responses necessary for an effective HCV vaccine against the different HCV genotypes
Externí odkaz:
https://doaj.org/article/beaef9146df446c3829409a68d4e5832
Publikováno v:
Experimental Gerontology. 107:116-125
Age-related changes in T-cell function are associated with a loss of influenza vaccine efficacy in older adults. Both antibody and cell-mediated immunity plays a prominent role in protecting older adults, particularly against the serious complication
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d77b792415304befe6311bf0a09faba2
https://doi.org/10.1016/j.exger.2017.09.015
https://doi.org/10.1016/j.exger.2017.09.015
Autor:
Terry D. Cyr, Tobias R. Kollmann, Shahzma Merani, Scott A. Halperin, David W. Scheifele, Lisa Walrond, Janet E. McElhaney, Arun Kumar
Publikováno v:
Human Vaccines & Immunotherapeutics. 13:2048-2057
Cellular immunity is important for protection against the serious complications of influenza in older adults. As it is unclear if newer influenza vaccines elicit greater cellular responses than standard vaccines, we compared responses to 2 standard a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c16ebaac7721619672fd29b9e2abba7
https://doi.org/10.1080/21645515.2017.1337615
https://doi.org/10.1080/21645515.2017.1337615
Publikováno v:
AIDS. 30:171-183
Antigen persistence due to HIV is a major source of inflammation and substantial immune activation, both of which are linked to accelerated aging. This illustrates the need to reduce immune activation in these patients and subsequently decrease the r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d9ea69908ef3384a4d56db5bd76d412
https://doi.org/10.1097/qad.0000000000000917
https://doi.org/10.1097/qad.0000000000000917
Autor:
Spyros A. Kalams, M. Azim Ansari, Simon Mallal, Andri Rauch, E Barnes, Louise Barnett, Ian James, Anne Plauzolles, Mark A. Pilkinton, Karen Fitzmaurice, Mina John, Elouise Gaylard, Heidi E. Drummer, Silvana Gaudieri, Pooja Deshpande, Dermot Kelleher, Katja Pfafferott, Andrew Lucas, Michaela Lucas, Wyatt J. McDonnell, Cody A. Chastain, Shahzma Merani, Vincent Pedergnana, Paul Klenerman, Amy Prosser
Publikováno v:
Scientific Reports
Lucas, Michaela; Deshpande, Pooja; James, Ian; Rauch, Andri; Pfafferott, Katja; Gaylard, Elouise; Merani, Shahzma; Plauzolles, Anne; Lucas, Andrew; McDonnell, Wyatt; Kalams, Spyros; Pilkinton, Mark; Chastain, Cody; Barnett, Louise; Prosser, Amy; Mallal, Simon; Fitzmaurice, Karen; Drummer, Heidi; Ansari, M. Azim; Pedergnana, Vincent; ... (2018). Evidence of CD4+ T cell-mediated immune pressure on the Hepatitis C virus genome. Scientific Reports, 8(1), p. 7224. Nature Publishing Group 10.1038/s41598-018-25559-6
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Scientific Reports, 2018, 8 (1), pp.7224. ⟨10.1038/s41598-018-25559-6⟩
Lucas, Michaela; Deshpande, Pooja; James, Ian; Rauch, Andri; Pfafferott, Katja; Gaylard, Elouise; Merani, Shahzma; Plauzolles, Anne; Lucas, Andrew; McDonnell, Wyatt; Kalams, Spyros; Pilkinton, Mark; Chastain, Cody; Barnett, Louise; Prosser, Amy; Mallal, Simon; Fitzmaurice, Karen; Drummer, Heidi; Ansari, M. Azim; Pedergnana, Vincent; ... (2018). Evidence of CD4+ T cell-mediated immune pressure on the Hepatitis C virus genome. Scientific Reports, 8(1), p. 7224. Nature Publishing Group 10.1038/s41598-018-25559-6
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Scientific Reports, 2018, 8 (1), pp.7224. ⟨10.1038/s41598-018-25559-6⟩
Hepatitis C virus (HCV)-specific T cell responses are critical for immune control of infection. Viral adaptation to these responses, via mutations within regions of the virus targeted by CD8+ T cells, is associated with viral persistence. However, id
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cacc2dfd3caf5077e3d86ba2c04ea74d
http://europepmc.org/articles/PMC5940905
http://europepmc.org/articles/PMC5940905
Publikováno v:
Reviews in Medical Virology. 25:175-186
In recent years, a critical role for β-galactoside-binding protein, Galectin-9 (Gal-9) has emerged in infectious disease, autoimmunity, and cancer. It is a ligand for T cell immunoglobulin mucin domain 3 (Tim-3), a type-I glycoprotein that is persis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd5d45bf4174cf8082ef9e292702420b
https://doi.org/10.1002/rmv.1832
https://doi.org/10.1002/rmv.1832
Autor:
Katja Pfafferott, Abha Chopra, D. Cooper, Silvana Gaudieri, Pooja Deshpande, Michaela Lucas, Shahzma Merani, Shay Leary, Fabio Luciani
Publikováno v:
Viral immunology. 30(7)
Host hepatitis C virus (HCV)-specific T cell responses and the ability of the virus to escape this response are important correlates of infection outcome. Understanding this host-viral interplay has been difficult given the often asymptomatic nature
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2f0276122d3090d798eb2bedbc77869
https://pubmed.ncbi.nlm.nih.gov/28530508
https://pubmed.ncbi.nlm.nih.gov/28530508