Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Shahzina Kanwal"'
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Lung cancer has the highest incidence of morbidity and mortality throughout the globe. A large number of patients are diagnosed with lung cancer at the later stages of the disease. This eliminates surgery as an option and places complete dependence o
Externí odkaz:
https://doaj.org/article/9a6bf061f0eb4a019fe82b285db02838
Autor:
Shahzina Kanwal, Xiangpeng Guo, Carl Ward, Giacomo Volpe, Baoming Qin, Miguel A. Esteban, Xichen Bao
Publikováno v:
Genomics, Proteomics & Bioinformatics, Vol 18, Iss 1, Pp 16-25 (2020)
The generation of induced pluripotent stem cells through somatic cell reprogramming requires a global reorganization of cellular functions. This reorganization occurs in a multi-phased manner and involves a gradual revision of both the epigenome and
Externí odkaz:
https://doaj.org/article/5680af886dea4e7790df7fe89915fff3
Autor:
Yunpan Li, David P. Ibañez, Wenxia Fan, Ping Zhao, Shuhan Chen, Mazid Md. Abdul, Yu Jiang, Lixin Fu, Zhiwei Luo, Zhenhua Liu, Yueli Yang, Jifeng Guo, Giacomo Volpe, Shahzina Kanwal, Dongye Wang, Beisha Tang, Wenjuan Li
Publikováno v:
Stem Cell Research, Vol 46, Iss , Pp 101845- (2020)
Mutations occurring in the gene body of PARK7 (encoding DJ-1/PARK7) cause autosomal recessive early-onset parkinsonism (AREP). These mutations produce a loss of function and have been reported to lead to dopaminergic neuron degeneration in the substa
Externí odkaz:
https://doaj.org/article/53af3126d2da48ccbd5a38643b4fbe4c
Autor:
Muqddas Tariq, Hao Liu, David P. Ibañez, Yunpan Li, Shuhan Chen, Mengling Jiang, Wenxia Fan, Ping Zhao, Zhiwei Luo, Dongye Wang, Shahzina Kanwal
Publikováno v:
Stem Cell Research, Vol 45, Iss , Pp - (2020)
Parkinson's disease (PD) is one of the most common neurodegenerative disorders and is characterized by the progressive degeneration of dopaminergic (DA) neurons in the substantia nigra. Loss of function mutations in PARK2 cause familial PD in an auto
Externí odkaz:
https://doaj.org/article/7cf38d542ed24c39a9693f8f97895588
Publikováno v:
PeerJ, Vol 6, p e5917 (2018)
Background A positive association between diabetes and breast cancer has been identified by various epidemiological and clinical studies. However, the possible molecular interactions between the two heterogeneous diseases have not been fully determin
Externí odkaz:
https://doaj.org/article/2ae828f9e7544e28b8c64c2b35df6ea9
Autor:
Muhammad Tariq Saeed, Jamil Ahmad, Shahzina Kanwal, Andreana N. Holowatyj, Iftikhar A. Sheikh, Rehan Zafar Paracha, Aamir Shafi, Amnah Siddiqa, Zurah Bibi, Mukaram Khan, Amjad Ali
Publikováno v:
PeerJ, Vol 4, p e2348 (2016)
The alteration of glucose metabolism, through increased uptake of glucose and glutamine addiction, is essential to cancer cell growth and invasion. Increased flux of glucose through the Hexosamine Biosynthetic Pathway (HBP) drives increased cellular
Externí odkaz:
https://doaj.org/article/1019672c9f3f4cc8b5b2420a2b9d9e60
Autor:
Shahzina Kanwal, Yann Fardini, Patrick Pagesy, Thierry N'tumba-Byn, Cécile Pierre-Eugène, Elodie Masson, Cornelia Hampe, Tarik Issad
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69150 (2013)
O-GlcNAcylation (addition of N-acetyl-glucosamine on serine or threonine residues) is a post-translational modification that regulates stability, activity or localization of cytosolic and nuclear proteins. O-linked N-acetylgluocosmaine transferase (O
Externí odkaz:
https://doaj.org/article/a4529715b4b24986966e08c9b46a6c7a
Autor:
Shahzina Kanwal, Jieyi Hu, Menghui Yin, Biliang Zhang, Jianwen Yuan, Yuan Lv, Xiangpeng Guo, Jin Meng, Xiwei Wang, Na Li, Yiwei Lai, Giacomo Volpe, Xichen Bao, Baoming Qin, Dongye Wang, Muqddas Tariq, Carl Ward, Zhiwei Luo, Miguel A. Esteban, Mengling Jiang
Publikováno v:
Nature Protocols. 16:5193-5219
Application of synthetic nucleoside analogues to capture newly transcribed RNAs has unveiled key features of RNA metabolism. Whether this approach could be adapted to isolate the RNA-bound proteome (RNA interactome) was, however, unexplored. We have
Autor:
Xueting Xu, Tanveer Ahmed, Lulu Wang, Xintao Cao, Zeyu Zhang, Ming Wang, Yuan Lv, Shahzina Kanwal, Muqddas Tariq, Runxia Lin, Hui Zhang, Yinghua Huang, Hao Peng, Danni Lin, Xue Shi, Didi Geng, Baohua Liu, Xiaofei Zhang, Wen Yi, Yan Qin, Miguel A Esteban, Baoming Qin
Publikováno v:
EMBO Rep
Mouse embryonic stem cells (mESCs) can self-renew indefinitely and maintain pluripotency. Inhibition of mechanistic target of rapamycin (mTOR) by the kinase inhibitor INK128 is known to induce paused pluripotency in mESCs cultured with traditional se
Publikováno v:
Journal of Molecular Cell Biology. 11:813-815