p38γ MAPK contributes to left ventricular remodeling after pathologic stress and disinhibits calpain through phosphorylation of calpastatin

Autor: Aminah A. Loonat, James Clark, Katharina Tilgner, Pelin Arabacilar, Nicholas T. Hertz, Max Thomas, Michael S. Marber, Negin Sarafraz-Shekary, Kevan M. Shokat, E Denise Martin, Alma L. Burlingame, Shahzan Uddin, Rebecca S. Levin

Publikováno v: Loonat, A A, Martin, E D, Sarafraz-Shekary, N, Tilgner, K, Hertz, N T, Levin, R, Shokat, K M, Burlingame, A L, Arabacilar, P, Uddin, S, Thomas, M, Marber, M S & Clark, J E 2019, ' p38γ MAPK contributes to left ventricular remodeling after pathologic stress and disinhibits calpain through phosphorylation of calpastatin ', Faseb Journal, vol. 33, no. 12, pp. 13131-13144 . https://doi.org/10.1096/fj.201701545R

Despite the high and preferential expression of p38γ MAPK in the myocardium, little is known about its function in the heart. The aim of the current study was to elucidate the physiologic and biochemical roles of p38γ in the heart. Expression and s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6495c6e9f2f2092f9b7c4ede0c6d39e
https://kclpure.kcl.ac.uk/ws/files/123773029/fj.201701545r.pdf