Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Shahryar K, Hekmatyar"'
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 7, Iss 7, Pp 658-666 (2005)
Effects of an alkylating anticancer drug, cyclophosphamide (Cp), on 23Na signal intensity (23Na SI) and water apparent diffusion coefficient (ADC) were examined in subcutaneously - implanted radiation-induced fibrosarcoma (RIF-1) tumors by in vivo23N
Externí odkaz:
https://doaj.org/article/d560fac0d42c4b1d95cbb2d6ad061dda
Publikováno v:
Archives of Toxicology. 88:47-64
Natural leaching processes and/or anthropogenic contamination can result in ground water concentrations of the essential metal manganese (Mn) that far exceed the current regulatory standards. Neurological consequences of Mn drinking water (DW) overex
Autor:
Asla Pitkänen, Olli Gröhn, Joanna K. Huttunen, Shahryar K. Hekmatyar, Risto A. Kauppinen, Juha-Pekka Niskanen, Neil P. Jerome, Antti M. Airaksinen
Publikováno v:
Epilepsia. 53:1245-1253
Summary Purpose: To investigate how kainic acid–induced epileptiform activity is related to hemodynamic changes probed by blood oxygenation level–dependent functional magnetic resonance imaging (BOLD fMRI). Methods: Epileptiform activity was indu
Autor:
Neil P. Jerome, Reza M. Salek, Shahryar K. Hekmatyar, Andrew C. Peet, Risto A. Kauppinen, Julian L. Griffin, Martin Wilson
Publikováno v:
British Journal of Cancer. 103:1297-1304
Human medulloblastomas exhibit diverse molecular pathology. Aberrant hedgehog signalling is found in 20–30% of human medulloblastomas with largely unknown metabolic consequences. Transgenic mice over-expressing smoothened (SMO) receptor in granule
Autor:
Mark A. Israel, Cong Ran, Shahryar K. Hekmatyar, Nathan P. Watson, Chelsea S. Place, Joana M. Murad, Risto A. Kauppinen
Publikováno v:
Journal of Biological Chemistry. 285:24164-24173
Inhibitor of DNA binding 4 (ID4) is a helix-loop-helix protein that heterodimerizes with basic helix-loop-helix transcription factors inhibiting their function. ID4 expression is important for adipogenic differentiation of the 3T3-L1 cell line, and i
Autor:
Hong Zhang, Yong Gao, Andriy M. Babsky, Judy R. James, Shahryar K. Hekmatyar, Stephen Topper, Navin Bansal
Publikováno v:
Magnetic Resonance in Medicine. 59:485-491
The mechanism of water and sodium apparent diffusion coefficient (ADC) changes in rat skeletal muscle during global ischemia was examined by in vivo 1H and 23Na magnetic resonance spectroscopy (MRS). The ADCs of Na+ and water are expected to have sim
Publikováno v:
Journal of Magnetic Resonance Imaging. 24:132-139
Purpose To examine the effects of the alkylating anticancer drug 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) on 23Na MRI and the water apparent diffusion coefficient (ADC) in subcutaneously- (sc-) implanted 9L glioma in rats. Materials and Methods 23
Publikováno v:
NMR in Biomedicine. 17:33-42
Most perfused tumor cell experiments are performed at 37 degrees C, the normal healthy body temperature. However, the temperature of subcutaneously implanted tumors in small animals is generally 29-33 degrees C when the rectal temperature of the anim
Publikováno v:
International Journal of Hyperthermia. 18:165-179
Non-invasive thermometry is pivotal to the future advances of regional hyperthermia as a cancer treatment modality. Current magnetic resonance (MR) thermometry methods suffer from poor thermal resolution due to relatively weak dependence of chemical
Autor:
Antti M, Airaksinen, Shahryar K, Hekmatyar, Neil, Jerome, Juha-Pekka, Niskanen, Joanna K, Huttunen, Asla, Pitkänen, Risto A, Kauppinen, Olli H, Gröhn
Publikováno v:
Epilepsia. 53(7)
To investigate how kainic acid-induced epileptiform activity is related to hemodynamic changes probed by blood oxygenation level-dependent functional magnetic resonance imaging (BOLD fMRI).Epileptiform activity was induced with kainic acid (KA) (10 m