Zobrazeno 1 - 10 of 13 pro vyhledávání: '"Shahroze Abbas"'
1
Akademický článek
GCSscore: an R package for differential gene expression analysis in Affymetrix/Thermo-Fisher whole transcriptome microarrays
Autor: Guy M. Harris, Shahroze Abbas, Michael F. Miles
Publikováno v: BMC Genomics, Vol 22, Iss 1, Pp 1-12 (2021)
Abstract Background Despite the increasing use of RNAseq for transcriptome analysis, microarrays remain a widely-used methodology for genomic studies. The latest generation of Affymetrix/Thermo-Fisher microarrays, the ClariomD/XTA and ClariomS array,
Externí odkaz: https://doaj.org/article/b25664a052ee4accbdb0c94ac21d1812
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2
Akademický článek
Intermittent Ethanol during Adolescence Leads to Lasting Behavioral Changes in Adulthood and Alters Gene Expression and Histone Methylation in the PFC
Autor: Jennifer T. Wolstenholme, Tariq Mahmood, Guy M. Harris, Shahroze Abbas, Michael F. Miles
Publikováno v: Frontiers in Molecular Neuroscience, Vol 10 (2017)
Adolescents primarily consume alcohol in binges, which can be particularly harmful to the developing frontal cortex and increase risk for an adult alcohol use disorder. We conducted a study investigating immediate and long lasting changes to the pref
Externí odkaz: https://doaj.org/article/462e53b1276946c096e337def2e1c225
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3
Anti-GD2 Antibodies Conjugated to IL15 and IL21 Mediate Potent Antitumor Cytotoxicity against Neuroblastoma
Autor: Rosa Nguyen, Xiyuan Zhang, Ming Sun, Shahroze Abbas, Charlie Seibert, Michael C. Kelly, Jack F. Shern, Carol J. Thiele
Publikováno v: Clin Cancer Res
Purpose:Half of the patients with high-risk neuroblastoma who receive GD2-targeted mAb do not achieve long-term remissions. Recently, the antibody hu14.18 has been linked to IL2 (hu14.18-IL2) to enhance its efficacy and shown promising preclinical an
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e2880179d23fefa8ceb6a3239d92949
https://doi.org/10.1158/1078-0432.ccr-22-0717
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6
Data from Anti-GD2 Antibodies Conjugated to IL15 and IL21 Mediate Potent Antitumor Cytotoxicity against Neuroblastoma
Autor: Carol J. Thiele, Jack F. Shern, Michael C. Kelly, Charlie Seibert, Shahroze Abbas, Ming Sun, Xiyuan Zhang, Rosa Nguyen
Purpose:Half of the patients with high-risk neuroblastoma who receive GD2-targeted mAb do not achieve long-term remissions. Recently, the antibody hu14.18 has been linked to IL2 (hu14.18-IL2) to enhance its efficacy and shown promising preclinical an
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b5583d4568ac60406978a1550674005
https://doi.org/10.1158/1078-0432.c.6532599
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7
Abstract 3563: SWI/SNF-associated DPF1 is a unique transcriptional regulator of malignant peripheral nerve sheath tumors
Autor: Bega Murray, Xiyuan Zhang, Shahroze Abbas, Haiyan Lei, Hilda Jafarah, Jack F. Shern
Publikováno v: Cancer Research. 83:3563-3563
Background: Malignant peripheral nerve sheath tumors (MPNST) are rare soft tissue sarcomas that are typically therapy resistant and associated with a poor prognosis. Genetic aberrations of the polycomb repressive complex 2 (PRC2) occur in up to 75% o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::472c70d204e887625386929e6e67e04e
https://doi.org/10.1158/1538-7445.am2023-3563
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8
Abstract 4635: Single cell definition of the immunogenic synapse between the tumorigenic schwann cells and tumor associated macrophages in Plexiform Neurofibroma
Autor: Thomas J. On, Xiyuan Zhang, Shahroze Abbas, John Shern
Publikováno v: Cancer Research. 83:4635-4635
Background: Patients with Neurofibromatosis Type 1 (NF1) frequently develop benign tumors called Plexiform neurofibromas (PN). Macrophages compose 30-50% of the total cellular composition of PNs and have previously been shown to play a critical role
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e7c18d2b461d747bcda896d20d0fcc29
https://doi.org/10.1158/1538-7445.am2023-4635
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9
GCSscore: an R package for differential gene expression analysis in Affymetrix/Thermo-Fisher whole transcriptome microarrays
Autor: Shahroze Abbas, Michael F. Miles, Guy M. Harris
Publikováno v: BMC Genomics, Vol 22, Iss 1, Pp 1-12 (2021)
BMC Genomics
Background Despite the increasing use of RNAseq for transcriptome analysis, microarrays remain a widely-used methodology for genomic studies. The latest generation of Affymetrix/Thermo-Fisher microarrays, the ClariomD/XTA and ClariomS array, provide
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c0d740c12bb41e0093955532460653a
https://doaj.org/article/b25664a052ee4accbdb0c94ac21d1812
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10
Abstract B011: Single cell CRISPR screen of malignant peripheral nerve sheath tumors identifies SWI/SNF genes of regulatory importance
Autor: Bega Murray, Xiyuan Zhang, Shahroze Abbas, Haiyan Lei, Hilda Jafarah, Michael C. Kelly, Jack F. Shern
Publikováno v: Cancer Research. 82:B011-B011
Background: Malignant peripheral nerve sheath tumors (MPNST) are rare and aggressive soft tissue sarcomas of the peripheral nervous system which are associated with a poor prognosis. Recurrent genetic mutations of the polycomb repressive complex 2 (P
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d7cd2c4eddbc6dd71837e57fb9631517
https://doi.org/10.1158/1538-7445.cancepi22-b011
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