Výsledky vyhledávání - "Shahrina Alam"

Co(salen)-Catalyzed Oxidation of Lignin Models to Form Benzoquinones and Benzaldehydes: A Computational and Experimental Study

Autor: Connor J. Cooper, Zhongyu Mou, Alan W. Rudie, Ryne C. Johnston, Alexander S. Ivanov, Joseph J. Bozell, Shahrina Alam, Vincent de Paul Nzuwah Nziko, David B. Turpin, Jerry M. Parks, Thomas Elder

Publikováno v: ACS Sustainable Chemistry & Engineering. 8:7225-7234

Lignin is a highly abundant polyphenolic polymer that imparts mechanical strength to plant biomass. Transition-metal complexes can catalyze lignin oxidation to produce value-added products, but low...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a3f13daf36f530f4884dd2a9641b9164
https://doi.org/10.1021/acssuschemeng.0c01970

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Labeling of Phosphatidylinositol Lipid Products in Cells through Metabolic Engineering by Using a Clickablemyo-Inositol Probe

Autor: Jennifer L. Morrell-Falvey, Adam J. Carr, Francisco N. Barrera, Shahrina Alam, Timothy W. Yokley, Cameron E. Workman, Daiane S. Alves, Michael D. Best, Kathrin Tscherch, Todd B. Reynolds, Chelsi D. Cassilly, Tanei J. Ricks

Publikováno v: ChemBioChem. 20:172-180

Phosphatidylinositol (PI) lipids control critical biological processes, so aberrant biosynthesis often leads to disease. As a result, the capability to track the production and localization of these compounds in cells is vital for elucidating their c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df39d6f7869ca59938cb649da58fd53c
https://doi.org/10.1002/cbic.201800248

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Classics in Chemical Neuroscience: Memantine

Autor: Kaelyn S. Lingenfelter, Shahrina Alam, Aaron M. Bender, Craig W. Lindsley

Publikováno v: ACS Chemical Neuroscience. 8:1823-1829

Memantine was the first breakthrough medication for the treatment of moderate to severe Alzheimer's disease (AD) patients and represents a fundamentally new mechanism of action (moderate-affinity, uncompetitive, voltage-dependent, N-methyl-d-aspartat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c5e0d35830adaf66ccba4ce32fa2b03
https://doi.org/10.1021/acschemneuro.7b00270

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A Clickable and Photocleavable Lipid Analogue for Cell Membrane Delivery and Release

Autor: Stuart A. Whitehead, Francisco N. Barrera, Christopher D. McNitt, Vladimir V. Popik, Andrew M. Bayer, Michael D. Best, Shahrina Alam, Daiane S. Alves

Publikováno v: Bioconjugate Chemistry. 26:1021-1031

For drug delivery purposes, the ability to conveniently attach a targeting moiety that will deliver drugs to cells and then enable controlled release of the active molecule after localization is desirable. Toward this end, we designed and synthesized

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abd5eb09d56eb57f55da406fd190845c
https://doi.org/10.1021/acs.bioconjchem.5b00044

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Artificial Membrane Fusion Triggered by Strain-Promoted Alkyne-Azide Cycloaddition

Autor: Adam J. Carr, Samuel I. Mattern-Schain, Stuart A. Whitehead, Vladimir V. Popik, Shahrina Alam, Christopher D. McNitt, Michael D. Best

Artificial systems for controlled membrane fusion applicable for drug delivery would ideally use triggers that are orthogonal to biology. To apply the strain-promoted alkyne-azide cycloaddition (SPAAC) to drive membrane fusion, oxo-dibenzocyclooctyne

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f00254aeadfa7fcef77e59b145ff07ea
https://europepmc.org/articles/PMC5990007/

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Triggered Liposomal Release through a Synthetic Phosphatidylcholine Analogue Bearing a Photocleavable Moiety Embedded within thesn-2 Acyl Chain

Autor: Shahrina Alam, Andrew M. Bayer, Michael D. Best, Samuel I. Mattern-Schain

Publikováno v: Chemistry - A European Journal. 20:3350-3357

Liposomes represent promising carriers for drug delivery applications. To maximize this potential, there has been significant interest in developing liposomal systems encapsulating molecular cargo that are highly stable until their contents are relea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6295c1cefdb4047aa309597555716697
https://doi.org/10.1002/chem.201304094

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Targeting and Triggered Release Using Lipid-Based Supramolecular Assemblies as Medicinal Nanocarriers

Autor: Shahrina Alam, Samuel I. Mattern-Schain, Michael D. Best

Lipid-based supramolecular assemblies have found widespread use as molecular cargo containers in biomedical delivery applications. This is due to the ability of self-assembled lipid systems such as liposomes to encapsulate molecules with a range of p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e4685a2487d700f6c8f25cd97722daed
https://doi.org/10.1016/b978-0-12-409547-2.12540-5

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Remarkable regioselectivity in microwave-enhanced palladium-catalyzed allylation reaction involving allyltrifluoroborates and aryl halides

Autor: Mohammad Al-Masum, Shahrina Alam

Publikováno v: Tetrahedron Letters. 50:5201-5204

An unprecedented cross-coupling reaction of potassium allyltrifluoroborates and aryl halides to the corresponding trans- β - methylstyrenes in the presence of PdCl 2 (d t bpf) catalyst under microwave heating was developed.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::681e43227f9db18adb418c0d84b372fb
https://doi.org/10.1016/j.tetlet.2009.06.134

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