Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Shahram Misaghi"'
Publikováno v:
Transportation Engineering, Vol 3, Iss , Pp 100045- (2021)
Several mechanistic-empirical software packages have been developed in the last two decades to address the impact of axle load and axle configuration on pavement responses and their performance. These software packages generally do not consider the v
Externí odkaz:
https://doaj.org/article/c8b015074e1d4cac9d9dd14c5d575beb
Publikováno v:
PLoS ONE, Vol 2, Iss 4, p e381 (2007)
BACKGROUND: Ubiquitin and ubiquitin-like proteins (Ubl) are designed to modify polypeptides in eukaryotes. Covalent binding of ubiquitin or Ubls to substrate proteins can be reversed by specific hydrolases. One particular set of cysteine proteases, t
Externí odkaz:
https://doaj.org/article/fad232993a3d44648ffd3f513bd10dc0
Autor:
Brian M. Castellano, Danming Tang, Scot Marsters, Cynthia Lam, Peter Liu, Christopher M. Rose, Wendy Sandoval, Avi Ashkenazi, Brad Snedecor, Shahram Misaghi
Publikováno v:
Biotechnology Progress.
Autor:
null Brian M. Castellano, null Danming Tang, null Scot Marsters, null Cynthia Lam, null Peter Liu, null Christopher M. Rose, null Wendy Sandoval, null Avi Ashkenazi, null Brad Snedecor, null Shahram Misaghi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16f31f912e144cb5ab118ee18fb00b7d
https://doi.org/10.1002/btpr.3354/v2/response1
https://doi.org/10.1002/btpr.3354/v2/response1
Autor:
Cynthia Lam, Joseph Carver, Domingos Ng, Dejin Zhan, Danming Tang, Thara Kandamkalam, Brad Snedecor, Gavin Barnard, Amy Shen, Shahram Misaghi
Publikováno v:
Biotechnology Progress.
Autor:
null Cynthia Lam, null Joseph Carver, null Domingos Ng, null Dejin Zhan, null Danming Tang, null Thara Kandamkalam, null Brad Snedecor, null Gavin Barnard, null Amy Shen, null Shahram Misaghi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3163387b122f243832586a83f93de3c4
https://doi.org/10.1002/btpr.3337/v2/response1
https://doi.org/10.1002/btpr.3337/v2/response1
Autor:
Danming Tang, Jane Gunson, Eric Tran, Cynthia Lam, Amy Shen, Brad Snedecor, Gavin Barnard, Shahram Misaghi
Publikováno v:
Biotechnology Progress. 38
Antigen binding fragments (Fab) are a promising class of therapeutics as they maintain high potency while having significantly smaller size relative to full-length antibodies. Because Fab molecules are aglycosylated, many expression platforms, includ
Autor:
Zijuan Lai, Feroza K. Choudhury, Danming Tang, Xiaorong Liang, Brian Dean, Shahram Misaghi, Dewakar Sangaraju
Publikováno v:
Biomedical chromatography : BMCREFERENCES. 36(5)
Chinese hamster ovary (CHO) cells have been widely used in the biopharmaceutical industry for production of therapeutic proteins. CHO cells in fed-batch cultures produce various amino acid-derived intermediate metabolites. These small molecule metabo
Autor:
Danming Tang, Cynthia Lam, Niels Bauer, Simon Auslaender, Brad Snedecor, Michael W. Laird, Shahram Misaghi
Publikováno v:
Biotechnology Progress. 38
In the field of therapeutic protein production, process intensification strategies entailing higher starting cell seeding densities, can potentially increase culture productivity, lower cost of goods and improve facility utilization. However, increas
Autor:
Niels Bauer, Benedikt Oswald, Maximilian Eiche, Lisa Schiller, Emma Langguth, Christian Schantz, Andrea Osterlehner, Amy Shen, Shahram Misaghi, Julian Stingele, Simon Ausländer
Publikováno v:
Synthetic Biology. 7
Complex therapeutic antibody formats, such as bispecifics (bsAbs) or cytokine fusions, may provide new treatment options in diverse disease areas. However, the manufacturing yield of these complex antibody formats in Chinese Hamster Ovary (CHO) cells