Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Shahram Emami"'
Publikováno v:
Pharmaceutical Sciences, Vol 30, Iss 4, Pp 469-477 (2024)
Background: Curcumin (CUR) has antimicrobial, anti-inflammatory, and antioxidant bioactivities and is a promising molecule to treat chronic wounds. However, CUR shows limited oral bioavailability due to low aqueous solubility and dissolution, chemica
Externí odkaz:
https://doaj.org/article/97b7039080da48a9ba18ecd39d8f137a
Publikováno v:
Advances in Pharmacological and Pharmaceutical Sciences, Vol 2024 (2024)
Curcumin has shown beneficial effects on pulmonary diseases with chronic inflammation or abnormal inflammatory responses, including chronic obstructive pulmonary disease, asthma, and pulmonary fibrosis. Clinical applications of curcumin are limited d
Externí odkaz:
https://doaj.org/article/9243dbdb79bb40f5a209e3e3751599dd
Publikováno v:
Pharmaceutical Sciences, Vol 29, Iss 3, Pp 252-254 (2023)
Externí odkaz:
https://doaj.org/article/35ad6350f34d4fa0bbf87631f2fafaf0
Autor:
Azin Jahangiri, Ali Nokhodchi, Kofi Asare-Addo, Erfan Salehzadeh, Shahram Emami, Shadi Yaqoubi, Hamed Hamishehkar
Publikováno v:
Biomedicines, Vol 11, Iss 6, p 1747 (2023)
Upregulation of cyclooxygenase (COX-2) plays an important role in lung cancer pathogenesis. Celecoxib (CLX), a selective COX-2 inhibitor, may have beneficial effects in COVID-19-induced inflammatory storms. The current study aimed to develop carrier-
Externí odkaz:
https://doaj.org/article/303329ebfdfb41afaad7abc99fbf03ba
Autor:
Khosro Adibkia, Solmaz Ghajar, Karim Osouli-Bostanabad, Niloufar Balaei, Shahram Emami, Mohammad Barzegar-Jalali
Publikováno v:
Advanced Pharmaceutical Bulletin, Vol 9, Iss 2, Pp 231-240 (2019)
Purpose: In the current study, electrospraying was directed as a novel alternative approach to improve the physicochemical attributes of gliclazide (GLC), as a poorly water-soluble drug, by creating nanocrystalline/amorphous solid dispersions (ESSs).
Externí odkaz:
https://doaj.org/article/ce088d8811304d81a6823a63e1835446
Autor:
Sevil Selselehjonban, Alireza Garjani, Karim Osouli-Bostanabad, Ali Tanhaei, Shahram Emami, Khosro Adibkia, Mohammad Barzegar-Jalali
Publikováno v:
Iranian Journal of Basic Medical Sciences, Vol 22, Iss 5, Pp 547-556 (2019)
Objective(s): This study was carried out to boost the pharmacologic influence of carvedilol (CAR) (as a poorly water-soluble drug) by developing CAR-eudragit® RS100 (Eud) nanofibers and nanobeads benefiting an electrospraying approach. Materials and
Externí odkaz:
https://doaj.org/article/d48735547cd74ce29c7f965c8822e7b7
Autor:
Khosro Adibkia, Sevil Selselehjonban, Shahram Emami, Karim Osouli-Bostanabad, Mohammad Barzegar-Jalali
Publikováno v:
BioImpacts, Vol 9, Iss 3, Pp 179-188 (2019)
Introduction: Modafinil (MDF) is used orally for the treatment of attention-deficit/hyperactivity disorder and narcolepsy. It holds low solubility and high permeability; therefore, improving its dissolution properties by preparing nanoformulations ca
Externí odkaz:
https://doaj.org/article/e6d3c952ad444d9898925640f9abc3a0
Publikováno v:
BioImpacts, Vol 8, Iss 4, Pp 305-320 (2018)
Introduction: Oral drug delivery is the most favored route of drug administration. However, poor oral bioavailability is one of the leading reasons for insufficient clinical efficacy. Improving oral absorption of drugs with low water solubility and/o
Externí odkaz:
https://doaj.org/article/3863982d2c794fd28f14a028b2bfd154
Autor:
Shahram Emami, Ali Shayanfar
Publikováno v:
Advanced Pharmaceutical Bulletin, Vol 11, Iss 3, Pp 578-579 (2021)
Externí odkaz:
https://doaj.org/article/6925b0e326764bad87519a4ee3922398
Autor:
Saeed Ghanbarzadeh, Aram Khalili, Abolghasem Jouyban, Shahram Emami, Yousef Javadzadeh, Mohammad Solhi, Hamed Hamishehkar
Publikováno v:
Research in Pharmaceutical Sciences, Vol 11, Iss 6, Pp 435-444 (2016)
Low solubility and dissolution rate are the primary challenges in the drug development which substantially impact the oral absorption and bioavailability of drugs. Due to the poor water solubility, Albendazole (ABZ) is poorly absorbed from the gastro
Externí odkaz:
https://doaj.org/article/0887c762fcff4c07a8f562a149c2558e