Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Shahrad Rod Rassekh"'
Autor:
Rebecca Ronsley, Celine D. Hounjet, Sylvia Cheng, Shahrad Rod Rassekh, Walter J. Duncan, Christopher Dunham, Jane Gardiner, Arvindera Ghag, Jeffrey P. Ludemann, David Wensley, Wingfield Rehmus, Michael A. Sargent, Juliette Hukin
Publikováno v:
Cancer Medicine, Vol 10, Iss 11, Pp 3556-3564 (2021)
Abstract Purpose To describe a series of children with extensive PNF or treatment refractory PLGG treated on a compassionate basis with trametinib. Methods We report on six patients with NF‐1 treated with trametinib on a compassionate basis at Brit
Externí odkaz:
https://doaj.org/article/778056853ba44d84ae5379fbb35ac161
Autor:
Rebecca Ronsley, Shahrad Rod Rassekh, Adam Fleming, Brianna Empringham, William Jennings, Carol Portwine, Sarah Burrow, Shayna Zelcer, Donna L. Johnston, Lehana Thabane, M. Constantine Samaan
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)
Abstract While children with brain tumors are surviving at record rates, survivors are at risk of cardiovascular disease and type 2 diabetes mellitus; these conditions may be driven by excess body fat. Adiponectin in an adipokine that is inversely as
Externí odkaz:
https://doaj.org/article/29199f71613041b7a3dd85f406e5a55e
A Canadian Study of Cisplatin Metabolomics and Nephrotoxicity (ACCENT): A Clinical Research Protocol
Autor:
Anshika Jain, Ryan Huang, Jasmine Lee, Natasha Jawa, Yong Jin Lim, Mike Guron, Sharon Abish, Paul C. Boutros, Michael Brudno, Bruce Carleton, Geoffrey D. E. Cuvelier, Lakshman Gunaratnam, Cheryl Ho, Khosrow Adeli, Sara Kuruvilla, Giles Lajoie, Geoffrey Liu, Paul C. Nathan, Shahrad Rod Rassekh, Michael Rieder, Sushrut S. Waikar, Stephen A. Welch, Matthew A. Weir, Eric Winquist, David S. Wishart, Alexandra P. Zorzi, Tom Blydt-Hansen, Michael Zappitelli, Bradley Urquhart
Publikováno v:
Canadian Journal of Kidney Health and Disease, Vol 8 (2021)
Background: Cisplatin, a chemotherapy used to treat solid tumors, causes acute kidney injury (AKI), a known risk factor for chronic kidney disease and mortality. AKI diagnosis relies on biomarkers which are only measurable after kidney damage has occ
Externí odkaz:
https://doaj.org/article/15b7986c609a42cb8982f5a706c42a37
Publikováno v:
Trials, Vol 19, Iss 1, Pp 1-11 (2018)
Abstract Background Clinical significance in a randomized controlled trial (RCT) can be determined using the minimal clinically important difference (MCID), which should inform the delta value used to determine sample size. The primary objective was
Externí odkaz:
https://doaj.org/article/8fddcfa264424f1b84f0cb3784803a51
Autor:
Kuan-Wen Wang, Russell J. de Souza, Adam Fleming, Donna L. Johnston, Shayna M. Zelcer, Shahrad Rod Rassekh, Sarah Burrow, Lehana Thabane, M. Constantine Samaan
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-7 (2018)
Abstract Children with brain tumors (CBT) are at higher risk of cardiovascular disease and type 2 diabetes compared to the general population, in which birth weight is a risk factor for these diseases. However, this is not known in CBT. The primary a
Externí odkaz:
https://doaj.org/article/fe91679aaf0d470f9e55db4385badbf6
Autor:
Kelly R. McMahon, Shahrad Rod Rassekh, Kirk R. Schultz, Maury Pinsk, Tom Blydt-Hansen, Cherry Mammen, Ross T. Tsuyuki, Prasad Devarajan, Geoff D. E. Cuvelier, Lesley G. Mitchell, Sylvain Baruchel, Ana Palijan, Bruce C. Carleton, Colin J. D. Ross, Michael Zappitelli
Publikováno v:
Canadian Journal of Kidney Health and Disease, Vol 4 (2017)
Background: Childhood cancer survivors experience adverse drug events leading to lifelong health issues. The Applying Biomarkers to Minimize Long-Term Effects of Childhood/Adolescent Cancer Treatment (ABLE) team was established to validate and apply
Externí odkaz:
https://doaj.org/article/32e16016fb1a4c4bb457e5058139481e
Publikováno v:
Case Reports in Pediatrics, Vol 2012 (2012)
A 10-year-old girl with trisomy 21 and complex congenital heart disease presented with acute lymphoblastic leukemia. Her chemotherapy required modifications due to poor baseline cardiac status and a mechanical prosthetic heart valve that was dependen
Externí odkaz:
https://doaj.org/article/a640f7d203d94600af8398fa811632d6
Publikováno v:
Therapeutic Drug Monitoring. 45:337-344
Publikováno v:
Pediatric Nephrology. 38:1667-1685
Autor:
Wingfield Rehmus, Walter J. Duncan, Rebecca Ronsley, Shahrad Rod Rassekh, Arvindera Ghag, Jane Gardiner, Celine D Hounjet, Juliette Hukin, Michael A. Sargent, Sylvia Cheng, Christopher Dunham, Jeffrey P. Ludemann, David Wensley
Publikováno v:
Cancer Medicine, Vol 10, Iss 11, Pp 3556-3564 (2021)
Cancer Medicine
Cancer Medicine
Purpose To describe a series of children with extensive PNF or treatment refractory PLGG treated on a compassionate basis with trametinib. Methods We report on six patients with NF‐1 treated with trametinib on a compassionate basis at British Colum