Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Shahper N. Khan"'
Autor:
Mohd W.A. Khan, Ahmed Al Otaibi, Subuhi Sherwani, Wahid A. Khan, Eida M. Alshammari, Salma A. Al-Zahrani, Mohd Saleem, Shahper N. Khan, Sultan Alouffi
Publikováno v:
Molecules, Vol 25, Iss 16, p 3675 (2020)
Aging causes gradual changes in free radicals, antioxidants, and immune-imbalance in the elderly. This study aims to understand links among aging, gluco-oxidative stress, and autoantibodies in asymptomatic individuals. In vitro glycation of human ser
Externí odkaz:
https://doaj.org/article/03f77062132b481b865f03381fe06dcf
Publikováno v:
Frontiers in Microbiology, Vol 8 (2017)
Candida sp. impelled opportunistic infection in immune-compromised patients ensuing from asymptomatic colonization to pathogenic forms. Moreover, slow spread of Candida species inducing refractory mucosal and invasive infections brings acute resistan
Externí odkaz:
https://doaj.org/article/9f77cea7ec104462a798030ee1a52473
Publikováno v:
Current Drug Targets. 22:1198-1206
Over the past several years, remarkable progress towards the recognition of new therapeutic targets in tumor cells has led to the discovery and development of newer scaffolds of anti-tumor drugs. The exploration and exploitation of epigenetic regulat
Autor:
Eida M. Alshammari, Abdulmohsen Khalaf Dhahi Alsukaibi, Salma Ahmed Al-Zahrani, Ahmed Al Otaibi, Subuhi Sherwani, Mohd Wajid Ali Khan, Wahid Ali Khan, Sultan Alouffi, Shahper N. Khan
Publikováno v:
Bioinformation
Human Vγ9/Vδ2 T cells (γδ T cells) are immune surveillance cells both in innate and adaptive immunity and are a possible target for anticancer therapies, which can induce immune responses in a variety of cancers. Small non-peptide antigens such a
Publikováno v:
Biochemical and Biophysical Research Communications. 518:459-464
Candida albicans frequently causes variety of superficial and invasive disseminated infections in HIV infected patients. Further, the emergence of non albicans species causing candidiasis predominantly in patients with advanced immune-suppression and
Publikováno v:
Drug Discovery Today. 24:179-188
Polycomb repressive complex 2 (PRC2) plays a significant part in histone methylation - trimethylating K27 at H3, an epigenetic hallmark of gene silencing. Inhibition of PRC2 has been reported as a promising strategy for the treatment of various cance
Autor:
Subuhi Sherwani, Khalid Al-Motair, Mohammad Saad Alam, Mohd Babu Khan, Saif A. Khan, Sultan Alouffi, Shahper N. Khan
Publikováno v:
Molecules
Molecules, Vol 26, Iss 2262, p 2262 (2021)
Molecules, Vol 26, Iss 2262, p 2262 (2021)
Glioblastoma (GB) is an aggressive cancer with high microvascular proliferation, resulting in accelerated invasion and diffused infiltration into the surrounding brain tissues with very low survival rates. Treatment options are often multimodal, such
Autor:
Robert M. Dean, Ehsan Malek, Hien Liu, Janice Reed, Wei Wei, Erica L. Campagnaro, Beth Faiman, Sherry Fada, Jason Valent, Kimberly Hamilton, Ronald Sobecks, Babal K. Jha, Matt Kalaycio, Jack Khouri, Mohammed S. Orloff, Reda Z. Mahfouz, Mary Ann Karam, Yap Chew, Christy J. Samaras, Frederic J. Reu, Yogen Saunthararajah, Dale Grabowski, Hillard M. Lazarus, Shahper N. Khan
Publikováno v:
Seminars in hematology. 58(1)
The DNA methyltransferase inhibitor azacytidine (aza) may reactivate pathways associated with plasma cell differentiation, cell cycle control, apoptosis, and immune recognition and thereby restore sensitivity to lenalidomide (len) and dexamethasone (
Publikováno v:
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 157
In the current scenario, frontline antibiotics are losing effectiveness against multidrug-resistant (MDR) bacteria because of the single mode of action. The accumulation of mutations and spread of antibiotic resistance markers among the bacteria resu
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 149:351-357
Sulfaguanidine (SG), belongs to the class of sulfonamide drug used as an effective antibiotic. In the present work, using crystal engineering approach two novel cocrystals of SG were synthesized (SG-TBA and SG-PT) with thiobarbutaric acid (TBA) and 1