Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Shahnaz Masani"'
Publikováno v:
Cell Reports, Vol 7, Iss 2, Pp 316-320 (2014)
Summary: Of the three DNA ligases present in all vertebrates, DNA ligase I (Lig1) has been considered essential for ligating Okazaki fragments during DNA replication and thereby essential for cell viability. Here, we report the striking finding that
Externí odkaz:
https://doaj.org/article/bbb6d8054d6a46fa962fce08ac01c879
Publikováno v:
Physiology. 38
At Michigan State University (MSU), the undergraduate capstone laboratory course for the physiology major places an emphasis on broad development opportunities for students. The course expands on prior knowledge from the undergraduate curriculum with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9abb9b59bee966de52110ba9689bf385
https://doi.org/10.1152/physiol.2023.38.s1.5731253
https://doi.org/10.1152/physiol.2023.38.s1.5731253
Publikováno v:
Nature. 599(7886)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::737645e379c70c18a944d6a98bed14f5
https://pubmed.ncbi.nlm.nih.gov/34815576
https://pubmed.ncbi.nlm.nih.gov/34815576
Publikováno v:
Proceedings of the National Academy of Sciences. 113:1261-1266
Nonhomologous end-joining (NHEJ) is the major DNA double-strand break (DSB) repair pathway in mammals and resolves the DSBs generated during both V(D)J recombination in developing lymphocytes and class switch recombination (CSR) in antigen-stimulated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e275f5087d2ce1ce7a0cbef02dc479b
https://doi.org/10.1073/pnas.1521630113
https://doi.org/10.1073/pnas.1521630113
Publikováno v:
Cell reports
Cell Reports, Vol 7, Iss 2, Pp 316-320 (2014)
Cell Reports, Vol 7, Iss 2, Pp 316-320 (2014)
Summary: Of the three DNA ligases present in all vertebrates, DNA ligase I (Lig1) has been considered essential for ligating Okazaki fragments during DNA replication and thereby essential for cell viability. Here, we report the striking finding that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cf7553ba80e979b8ed565101de45ba0
https://doi.org/10.1016/j.celrep.2014.03.024
https://doi.org/10.1016/j.celrep.2014.03.024
Publikováno v:
Proceedings of the National Academy of Sciences. 108:11584-11589
Ig class-switch recombination (CSR) is directed by the long and repetitive switch regions and requires activation-induced cytidine deaminase (AID). One of the conserved switch-region sequence motifs (AGCT) is a preferred site for AID-mediated DNA-cyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb05706e8199651a62fead36707bdb60
https://doi.org/10.1073/pnas.1018726108
https://doi.org/10.1073/pnas.1018726108
Publikováno v:
The Journal of Immunology. 185:1379-1381
Ig class switch recombination (CSR) and somatic hypermutation require activation-induced cytidine deaminase (AID). The search for AID-interaction factors has been a major research effort in the field, as the mechanism of preferential targeting of AID
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::beae21c86c508df110e2a10fccd64dd6
https://doi.org/10.4049/jimmunol.1001643
https://doi.org/10.4049/jimmunol.1001643
Publikováno v:
Molecular and cellular biology. 33(7)
Immunoglobulin (Ig) class switch recombination (CSR) is initiated by activation-induced cytidine deaminase (AID) that catalyzes numerous DNA cytosine deaminations within switch regions. The resulting uracils are processed by uracil base excision and/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2303b019b54fb21b05921f0870c8ff0
https://pubmed.ncbi.nlm.nih.gov/23382073
https://pubmed.ncbi.nlm.nih.gov/23382073