Bivalent norovirus mRNA vaccine elicits cellular and humoral responses protecting human enteroids from GII.4 infection.

Autor: Atochina-Vasserman EN; Institue for RNA Innovation, the University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA. atochina@pennmedicine.upenn.edu., Lindesmith LC; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Mirabelli C; Department of Microbiology and Immunology, University of Michigan, Ann Arbor, MI, USA., Ona NA; Institue for RNA Innovation, the University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Reagan EK; Institue for RNA Innovation, the University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Brewer-Jensen PD; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Mercado-Lopez X; Institue for RNA Innovation, the University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Shahnawaz H; Institue for RNA Innovation, the University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Meshanni JA; Institue for RNA Innovation, the University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Baboo I; Institue for RNA Innovation, the University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Mallory ML; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Zweigart MR; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., May SR; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Mui BL; Acuitas Therapeutics Inc, Vancouver, B.C., Canada., Tam YK; Acuitas Therapeutics Inc, Vancouver, B.C., Canada., Wobus CE; Department of Microbiology and Immunology, University of Michigan, Ann Arbor, MI, USA., Baric RS; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Weissman D; Institue for RNA Innovation, the University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.

Publikováno v: NPJ vaccines [NPJ Vaccines] 2024 Oct 01; Vol. 9 (1), pp. 182. Date of Electronic Publication: 2024 Oct 01.

Scenario Of Outsourcing of Various Services in Teaching Hospitals of India.

Autor: Bhat, Sajad H., Jan, Farooq A., Khan, Shahnawaz H., Mufti, Samina, Khan, Azmat, Hamid, Sajad

Publikováno v: Journal of Cardiovascular Disease Research (Journal of Cardiovascular Disease Research); 2022, Vol. 13` Issue 8, p1072-1081, 10p

Added to pre-existing inflammation, mRNA-lipid nanoparticles induce inflammation exacerbation (IE).

Autor: Parhiz H; Division of Infectious Diseases, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. Electronic address: parhizh@pennmedicine.upenn.edu., Brenner JS; Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Department of Medicine, Division of Pulmonary, Allergy, and Critical Care Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. Electronic address: Jacob.brenner@pennmedicine.upenn.edu., Patel PN; Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Papp TE; Division of Infectious Diseases, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Shahnawaz H; Division of Infectious Diseases, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Li Q; Division of Infectious Diseases, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Shi R; Division of Infectious Diseases, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Zamora ME; Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Department of Medicine, Division of Pulmonary, Allergy, and Critical Care Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Yadegari A; Division of Infectious Diseases, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Marcos-Contreras OA; Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Natesan A; Division of Infectious Diseases, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Pardi N; Division of Infectious Diseases, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Shuvaev VV; Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Kiseleva R; Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Myerson JW; Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Uhler T; Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Riley RS; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA., Han X; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA., Mitchell MJ; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA; Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Institute for Regenerative Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Lam K; Genevant Sciences Corporation, Vancouver, BC V5T 4T5, Canada., Heyes J; Genevant Sciences Corporation, Vancouver, BC V5T 4T5, Canada., Weissman D; Division of Infectious Diseases, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. Electronic address: dreww@pennmedicine.upenn.edu., Muzykantov VR; Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. Electronic address: muzykant@pennmedicine.upenn.edu.

Publikováno v: Journal of controlled release : official journal of the Controlled Release Society [J Control Release] 2022 Apr; Vol. 344, pp. 50-61. Date of Electronic Publication: 2021 Dec 23.

One-Component Multifunctional Sequence-Defined Ionizable Amphiphilic Janus Dendrimer Delivery Systems for mRNA.

Autor: Zhang D; Roy & Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6323, United States., Atochina-Vasserman EN; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States., Maurya DS; Roy & Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6323, United States., Huang N; Roy & Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6323, United States., Xiao Q; Roy & Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6323, United States., Ona N; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States., Liu M; Roy & Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6323, United States., Shahnawaz H; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States., Ni H; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States., Kim K; Department of Materials Science & Engineering, University of Delaware, Newark, Delaware 19716, United States., Billingsley MM; Department of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6321, United States., Pochan DJ; Department of Materials Science & Engineering, University of Delaware, Newark, Delaware 19716, United States., Mitchell MJ; Department of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6321, United States., Weissman D; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States., Percec V; Roy & Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6323, United States.

Publikováno v: Journal of the American Chemical Society [J Am Chem Soc] 2021 Aug 11; Vol. 143 (31), pp. 12315-12327. Date of Electronic Publication: 2021 Jul 29.

Dendrimers, Dendrons, and the Dendritic State: Reflection on the Last Decade with Expected New Roles in Pharma, Medicine, and the Life Sciences.

Autor: Tomalia, Donald A.^1,2,3 (AUTHOR) donald.tomalia@gmail.com

Publikováno v: Pharmaceutics. Dec2024, Vol. 16 Issue 12, p1530. 35p.