Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Shahira F El-Menshawe"'
Autor:
Shahira F. El Menshawe, Khaled Shalaby, Mohammed H. Elkomy, Heba M. Aboud, Yasmin M. Ahmed, Abdelmeged A. Abdelmeged, Marwa Elkarmalawy, Mahmoud A. Abou Alazayem, Amani M. El Sisi
Publikováno v:
International Journal of Pharmaceutics: X, Vol 7, Iss , Pp 100225- (2024)
Celecoxib (CLX), a selective inhibitor for cyclooxygenase 2 (COX-2), has manifested potential activity against diverse types of cancer. However, low bioavailability and cardiovascular side effects remain the major challenges that limit its exploitati
Externí odkaz:
https://doaj.org/article/18ff790bc59241c08c65b14e5a612d8d
Publikováno v:
Pharmaceuticals, Vol 17, Iss 10, p 1275 (2024)
Background/Objectives: Nintedanib (NTD), a triple tyrosine kinase receptor inhibitor, is the recommended first-line tackling option for idiopathic pulmonary fibrosis (IPF). Nevertheless, the adequacy of NTD is curtailed by issues associated with its
Externí odkaz:
https://doaj.org/article/9384c8f7547a4abe8c429dd41f8f2719
Autor:
Mohammed H. Elkomy, Shahira F. El Menshawe, Rasha M. Kharshoum, Amany M. Abdeltwab, Raghda R. S. Hussein, Doaa S. Hamad, Izzeddin Alsalahat, Heba M. Aboud
Publikováno v:
Drug Delivery, Vol 29, Iss 1, Pp 2058-2071 (2022)
Asthma represents a globally serious non-communicable ailment with significant public health outcomes for both pediatrics and adults triggering vast morbidity and fatality in critical cases. The β2-adrenoceptor agonist, terbutaline sulfate (TBN), is
Externí odkaz:
https://doaj.org/article/e006962feb9b40a79a1dcb7d84abbe21
Autor:
Shahira F. El Menshawe, Mohamed M. Nafady, Heba M. Aboud, Rasha M. Kharshoum, Asmaa Mohammed M. Hussein Elkelawy, Doaa S. Hamad
Publikováno v:
Drug Delivery, Vol 26, Iss 1, Pp 1140-1154 (2019)
The current study aimed to encapsulate fluvastatin sodium (FVS), a member of the statins family possessing pleiotropic effects in rheumatoid arthritis (RA), into spanlastic nanovesicles (SNVs) for transdermal delivery. This novel delivery could surmo
Externí odkaz:
https://doaj.org/article/14537b7f9b0a48c0af7baf9189728f23
Publikováno v:
Drug Delivery, Vol 24, Iss 1, Pp 781-791 (2017)
Loratadine (LTD) is an antihistaminic drug that suffers limited solubility, poor oral bioavailability (owing to extensive first-pass metabolism), and highly variable oral absorption. This study was undertaken to develop and statistically optimize tra
Externí odkaz:
https://doaj.org/article/b364e7c04ee043a8a82597974db06293
Autor:
Marwa Elkarmalawy, Mahmoud H. Teaima, Mohamed A. El-Nabarawi, Shahira F El-Menshawe, Mohamed M. Nafady
Publikováno v:
International Journal of Nanomedicine
Mohamed El-Nabarawi,1 Mohamed Nafady,2 Shahira Elmenshawe,3 Marwa Elkarmalawy,4 Mahmoud Teaima1 1Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Cairo University, Cairo, Egypt; 2Department of Pharmaceutics and Clinical Pharm
Autor:
Rasha M Kharshoum, Mohammed H. Elkomy, Amany M. Abdeltwab, Heba M. Aboud, Shahira F. El Menshawe
Publikováno v:
Drug Delivery and Translational Research. 10:471-485
The objective of the present work was to formulate, optimize, and evaluate transdermal terbutaline sulfate (TBN)-loaded bilosomes (BLS) in gel, compared to conventional oral TBN solution and transdermal gel loaded with free TBN, aiming at evading the
Publikováno v:
Journal of Drug Delivery Science and Technology. 52:687-701
For the treatment of atopic eczema, the drug penetration of the relevant skin layers is considered to be a major scientific concern. In this study, a new formulation which is based on positively charged ethosomes as drug carriers were prepared and ev
Publikováno v:
International Journal of Nanomedicine
Purpose Herbal supplements are currently available as a safer alternative to manage obesity, which has become a rising problem over the recent years. Many chemical drugs on the market are designed to prevent or manage obesity but high cost, low effic
Autor:
Mohammed H. Elkomy, Ahmed S. G. Srag El-Din, Shahira F El-Menshawe, Abdelkhalik Ali Halawa, Adel A. Ali
Publikováno v:
Drug Delivery and Translational Research. 8:165-177
The aim of this study was to develop and optimize a betahistine dihydrochloride (BH) thermoreversible bioadhesive gel intended for transdermal delivery. The gels were obtained via cold method. A full factorial design was employed to investigate the j