Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Shahin Tajeri"'
Autor:
Khawla Elati, Shahin Tajeri, Robert M. Mugo, Isaiah Obara, Mohamed Aziz Darghouth, Erich Zweygarth, Ard Menzo Nijhof
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Theileria annulata is a protozoan parasite with a complex life cycle involving a bovine host and a tick vector. It is transmitted by Hyalomma ticks and is the causative agent of tropical theileriosis, a debilitating and often fatal disease i
Externí odkaz:
https://doaj.org/article/dd0b59d2928a40ed847b7a7961b659e4
Autor:
Khawla Elati, Shahin Tajeri, Isaiah Obara, Moez Mhadhbi, Erich Zweygarth, Mohamed Aziz Darghouth, Ard Menzo Nijhof
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract The apicomplexan parasite Theileria annulata is transmitted by Hyalomma ticks and causes an acute lymphoproliferative disease that is invariably lethal in exotic cattle breeds. The unique ability of the schizont stage of T. annulata to trans
Externí odkaz:
https://doaj.org/article/0c3c4239a3e646d98a3ab6cf48f0855a
Publikováno v:
PLoS ONE, Vol 19, Iss 4 (2024)
Externí odkaz:
https://doaj.org/article/203260314bcb429eb58e69fbbe79211c
Autor:
Shahin Tajeri, Laurence Momeux, Benjamin Saintpierre, Sara Mfarrej, Alexander Chapple, Tobias Mourier, Brian Shiels, Frédéric Ariey, Arnab Pain, Gordon Langsley
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract A fungal metabolite, FR235222, specifically inhibits a histone deacetylase of the apicomplexan parasite Toxoplasma gondii and TgHDAC3 has emerged as a key factor regulating developmental stage transition in this species. Here, we exploited F
Externí odkaz:
https://doaj.org/article/b9dd82b8dc624f799c5869c9c2809f6c
Autor:
Malak Haidar, Shahin Tajeri, Laurence Momeux, Tobias Mourier, Fathia Ben-Rached, Sara Mfarrej, Zineb Rchiad, Arnab Pain, Gordon Langsley
Publikováno v:
mSphere, Vol 8, Iss 2 (2023)
ABSTRACT MicroRNAs (miRNAs) are small noncoding RNAs that can play critical roles in regulating various cellular processes, including during many parasitic infections. Here, we report a regulatory role for miR-34c-3p in cAMP-independent regulation of
Externí odkaz:
https://doaj.org/article/5923448cb02e41e5afce276252ffe6f2
Autor:
Nathanaël Saison, Jean-François Franetich, Yudi T. Pinilla, Anton Hoffmann, Stravensky T. Boussougou-Sambe, Barclaye Ngossanga, Maurel Tefit, Kutub Ashraf, Nadia Amanzougaghene, Shahin Tajeri, Ayola A. Adegnika, Dominique Mazier, Steffen Borrmann
Publikováno v:
Pharmaceutics, Vol 14, Iss 12, p 2794 (2022)
Methylene blue (MB) is the oldest synthetic anti-infective. Its high potency against asexual and sexual stages of malaria parasites is well documented. This study aimed to investigate possible additional activities of MB in interfering with parasite
Externí odkaz:
https://doaj.org/article/bf6e23456ad148e58fdbae71124822a1
Autor:
Henriette Bosson-Vanga, Nicolas Primas, Jean-François Franetich, Catherine Lavazec, Lina Gomez, Kutub Ashraf, Maurel Tefit, Valérie Soulard, Nathalie Dereuddre-Bosquet, Roger Le Grand, Mélanie Donnette, Romain Mustière, Nadia Amanzougaghene, Shahin Tajeri, Peggy Suzanne, Aurélie Malzert-Fréon, Sylvain Rault, Patrice Vanelle, Sébastien Hutter, Anita Cohen, Georges Snounou, Pierre Roques, Nadine Azas, Prisca Lagardère, Vincent Lisowski, Nicolas Masurier, Michel Nguyen, Lucie Paloque, Françoise Benoit-Vical, Pierre Verhaeghe, Dominique Mazier
Publikováno v:
Microbiology Spectrum, Vol 9, Iss 2 (2021)
ABSTRACT Human malaria infection begins with a one-time asymptomatic liver stage followed by a cyclic symptomatic blood stage. For decades, the research for novel antimalarials focused on the high-throughput screening of molecules that only targeted
Externí odkaz:
https://doaj.org/article/b8042b3d70524640b19a2ebd49c5a820
Autor:
Nadia Amanzougaghene, Shahin Tajeri, Samir Yalaoui, Audrey Lorthiois, Valérie Soulard, Audrey Gego, Armelle Rametti, Véronica Risco-Castillo, Alicia Moreno, Maurel Tefit, Geert-Jan van Gemert, Robert W. Sauerwein, Jean-Christophe Vaillant, Philippe Ravassard, Jean-Louis Pérignon, Patrick Froissard, Dominique Mazier, Jean-François Franetich
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Hepatocyte invasion by Plasmodium sporozoites represents a promising target for innovative antimalarial therapy, but the molecular events mediating this process are still largely uncharacterized. We previously showed that Plasmodium falciparum sporoz
Externí odkaz:
https://doaj.org/article/2754b233e983418089572f00cf630310
Autor:
Dyhia Amrane, Christophe-Sébastien Arnold, Sébastien Hutter, Julen Sanz-Serrano, Miguel Collia, Amaya Azqueta, Lucie Paloque, Anita Cohen, Nadia Amanzougaghene, Shahin Tajeri, Jean-François Franetich, Dominique Mazier, Françoise Benoit-Vical, Pierre Verhaeghe, Nadine Azas, Patrice Vanelle, Cyrille Botté, Nicolas Primas
Publikováno v:
Pharmaceuticals, Vol 14, Iss 8, p 724 (2021)
The malaria parasite harbors a relict plastid called the apicoplast. Although not photosynthetic, the apicoplast retains unusual, non-mammalian metabolic pathways that are essential to the parasite, opening up a new perspective for the development of
Externí odkaz:
https://doaj.org/article/5dd08eb5d7524519bd2a427e208e3020
Publikováno v:
Onderstepoort Journal of Veterinary Research, Vol 86, Iss 1, Pp e1-e6 (2019)
Malignant ovine theileriosis is caused by Theileria lestoquardi, which is highly pathogenic in sheep. Theileriosis involves different organs in ruminants. Little is known about the role of proinflammatory cytokines in the pathogenesis of T. lestoquar
Externí odkaz:
https://doaj.org/article/d96e90e756e140bda5caba6f4f2ac7ef