Parthenolide ameliorates 3-nitropropionic acid-induced Huntington's disease-like aberrations via modulating NLRP3 inflammasome, reducing microglial activation and inducing astrocyte shifting.

Autor: Noureldeen ME; Biochemistry Department, Faculty of Pharmacy, Cairo University, Kasr El-Ainy St., Cairo, 11562, Egypt., Shahin NN; Biochemistry Department, Faculty of Pharmacy, Cairo University, Kasr El-Ainy St., Cairo, 11562, Egypt., Amin HAA; Pathology Department, Faculty of Medicine, Helwan University, Cairo, 11795, Egypt., El-Sawalhi MM; Biochemistry Department, Faculty of Pharmacy, Cairo University, Kasr El-Ainy St., Cairo, 11562, Egypt., Ghaiad HR; Biochemistry Department, Faculty of Pharmacy, Cairo University, Kasr El-Ainy St., Cairo, 11562, Egypt. heba.mosalam@pharma.cu.edu.eg.

Publikováno v: Molecular medicine (Cambridge, Mass.) [Mol Med] 2024 Sep 26; Vol. 30 (1), pp. 158. Date of Electronic Publication: 2024 Sep 26.

Association of long noncoding RNA H19 rs2839698 C/T with hepatitis B virus infection and hepatocellular carcinoma risk.

Autor: Motawi TK; Biochemistry Department, Faculty of Pharmacy, Cairo University, Cairo, Egypt., Mady AE; Pharmacy Department, National Liver Institute, Menoufia University, Shebin El-Kom, Egypt., Elhelbawy M; Hepatology and Gastroenterology Department, National Liver Institute, Menoufia University, Shebin El-Kom, Egypt., Talaat RM; Molecular Biology Department, University of Sadat City (USC), Sadat City, Egypt., Shahin NN; Biochemistry Department, Faculty of Pharmacy, Cairo University, Cairo, Egypt.

Publikováno v: Journal of biochemical and molecular toxicology [J Biochem Mol Toxicol] 2024 Apr; Vol. 38 (4), pp. e23673.

Phosphatidylethanolamines Are Associated with Nonalcoholic Fatty Liver Disease (NAFLD) in Obese Adults and Induce Liver Cell Metabolic Perturbations and Hepatic Stellate Cell Activation.

Autor: Shama S; Department of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI 48201, USA.; Cell-Based Analysis Unit, Reference Laboratory, Egyptian Drug Authority, Cairo 12618, Egypt., Jang H; Biostatistics and Bioinformatics Core, Department of Oncology, Karmanos Cancer Institute, Wayne State University, Detroit, MI 48201, USA.; Department of Oncology, Wayne State University School of Medicine, Detroit, MI 48201, USA., Wang X; Department of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI 48201, USA., Zhang Y; Department of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI 48201, USA., Shahin NN; Department of Biochemistry, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt., Motawi TK; Department of Biochemistry, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt., Kim S; Biostatistics and Bioinformatics Core, Department of Oncology, Karmanos Cancer Institute, Wayne State University, Detroit, MI 48201, USA.; Department of Oncology, Wayne State University School of Medicine, Detroit, MI 48201, USA., Gawrieh S; Division of Gastroenterology and Hepatology, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA., Liu W; Department of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI 48201, USA.; Department of Oncology, Wayne State University School of Medicine, Detroit, MI 48201, USA.; Department of Pharmacology, Wayne State University School of Medicine, Detroit, MI 48201, USA.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2023 Jan 05; Vol. 24 (2). Date of Electronic Publication: 2023 Jan 05.

A Nano-Liposomal Formulation of Caffeic Acid Phenethyl Ester Modulates Nrf2 and NF-κβ Signaling and Alleviates Experimentally Induced Acute Pancreatitis in a Rat Model.

Autor: Shahin NN; Department of Biochemistry, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt., Shamma RN; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt., Ahmed IS; Department of Pharmaceutics & Pharmaceutical Technology, College of Pharmacy, University of Sharjah, Sharjah 27272, United Arab Emirates.; Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah 27272, United Arab Emirates.

Publikováno v: Antioxidants (Basel, Switzerland) [Antioxidants (Basel)] 2022 Aug 07; Vol. 11 (8). Date of Electronic Publication: 2022 Aug 07.

Time-based investigation of urinary metabolic markers for Type 2 diabetes: Metabolomics approach for diabetes management.

Autor: Hanafy MM; Therapeutic Chemistry Department, Pharmaceutical and Drug Industries Research Division, National Research Centre, Cairo, Egypt., Lindeque JZ; Human Metabolomics, Faculty of Natural and Agricultural Sciences, North-West University, Potchefstroom Campus, Potchefstroom, South Africa., El-Maraghy SA; Biochemistry Department, Faculty of Pharmacy, Cairo University, Cairo, Egypt., Abdel-Hamid AZ; Therapeutic Chemistry Department, Pharmaceutical and Drug Industries Research Division, National Research Centre, Cairo, Egypt., Shahin NN; Biochemistry Department, Faculty of Pharmacy, Cairo University, Cairo, Egypt.

Publikováno v: BioFactors (Oxford, England) [Biofactors] 2021 Jul; Vol. 47 (4), pp. 645-657. Date of Electronic Publication: 2021 Apr 09.