Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Shahin Hassanzadeh"'
Autor:
Brian Walitt, Komudi Singh, Samuel R. LaMunion, Mark Hallett, Steve Jacobson, Kong Chen, Yoshimi Enose-Akahata, Richard Apps, Jennifer J. Barb, Patrick Bedard, Robert J. Brychta, Ashura Williams Buckley, Peter D. Burbelo, Brice Calco, Brianna Cathay, Li Chen, Snigdha Chigurupati, Jinguo Chen, Foo Cheung, Lisa M. K. Chin, Benjamin W. Coleman, Amber B. Courville, Madeleine S. Deming, Bart Drinkard, Li Rebekah Feng, Luigi Ferrucci, Scott A. Gabel, Angelique Gavin, David S. Goldstein, Shahin Hassanzadeh, Sean C. Horan, Silvina G. Horovitz, Kory R. Johnson, Anita Jones Govan, Kristine M. Knutson, Joy D. Kreskow, Mark Levin, Jonathan J. Lyons, Nicholas Madian, Nasir Malik, Andrew L. Mammen, John A. McCulloch, Patrick M. McGurrin, Joshua D. Milner, Ruin Moaddel, Geoffrey A. Mueller, Amrita Mukherjee, Sandra Muñoz-Braceras, Gina Norato, Katherine Pak, Iago Pinal-Fernandez, Traian Popa, Lauren B. Reoma, Michael N. Sack, Farinaz Safavi, Leorey N. Saligan, Brian A. Sellers, Stephen Sinclair, Bryan Smith, Joseph Snow, Stacey Solin, Barbara J. Stussman, Giorgio Trinchieri, Sara A. Turner, C. Stephenie Vetter, Felipe Vial, Carlotta Vizioli, Ashley Williams, Shanna B. Yang, Center for Human Immunology, Autoimmunity, and Inflammation (CHI) Consortium, Avindra Nath
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-29 (2024)
Abstract Post-infectious myalgic encephalomyelitis/chronic fatigue syndrome (PI-ME/CFS) is a disabling disorder, yet the clinical phenotype is poorly defined, the pathophysiology is unknown, and no disease-modifying treatments are available. We used
Externí odkaz:
https://doaj.org/article/a14b918b7de649e6975c4ac14fdd7aa8
Autor:
Jing Wu, Komudi Singh, Amy Lin, Allison M. Meadows, Kaiyuan Wu, Vivian Shing, Maximilian Bley, Shahin Hassanzadeh, Rebecca D. Huffstutler, Mark S. Schmidt, Luz P. Blanco, Rong Tian, Charles Brenner, Mehdi Pirooznia, Mariana J. Kaplan, Michael N. Sack
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 5 (2022)
BACKGROUND Fasting and NAD+-boosting compounds, including NAD+ precursor nicotinamide riboside (NR), confer antiinflammatory effects. However, the underlying mechanisms and therapeutic potential are incompletely defined.METHODS We explored the underl
Externí odkaz:
https://doaj.org/article/a5920c2523044c81b76b48c3c78216ac
Autor:
Komudi Singh, Yun-Ching Chen, Shahin Hassanzadeh, Kim Han, Jennifer T. Judy, Fayaz Seifuddin, Ilker Tunc, Michael N. Sack, Mehdi Pirooznia
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Analyzing host cells' transcriptional response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection will help delineate biological processes underlying viral pathogenesis. First, analysis of expression profiles of lung cell lines
Externí odkaz:
https://doaj.org/article/e2aa9d64bb2d4c8fa16c61b7f3c3cd80
Autor:
Kira Patterson, Jeanette Beers, Kaari L. Linask, Yongshun Lin, Shahin Hassanzadeh, Michael N. Sack, Jizhong Zou
Publikováno v:
Stem Cell Research, Vol 41, Iss , Pp - (2019)
Human-derived induced pluripotent stem cells (iPSCs) have proven to be indispensable in cardiovascular drug development, disease modeling, and developmental biology research. For this reason, it is particularly useful to develop wild-type iPSC lines
Externí odkaz:
https://doaj.org/article/56d28cc25c5640d6af1a35644d206ccc
Autor:
Kim Han, Shahin Hassanzadeh, Komudi Singh, Sara Menazza, Tiffany T. Nguyen, Mark V. Stevens, An Nguyen, Hong San, Stasia A. Anderson, Yongshun Lin, Jizhong Zou, Elizabeth Murphy, Michael N. Sack
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract The regulatory control of cardiac endoplasmic reticulum (ER) stress is incompletely characterized. As ER stress signaling upregulates the E3-ubiquitin ligase Parkin, we investigated the role of Parkin in cardiac ER stress. Parkin knockout mi
Externí odkaz:
https://doaj.org/article/e74432eb6d7b4605b5186f619f445cc1
Autor:
Angelique Biancotto, Kaiyuan Wu, Kim Han, Nehal N. Mehta, Komudi Singh, Jinguo Chen, Shahin Hassanzadeh, Katherine E. R. Stagliano, Pradeep K. Dagur, Michael N. Sack, Matthew J. Rodman, Ankit Saxena, Heather L. Teague, Rebecca D. Huffstutler, Fayaz Seifuddin, An Nguyen, Mehdi Pirooznia, J. Philip McCoy
Publikováno v:
Nature metabolism
Intermittent fasting blunts inflammation in asthma1 and rheumatoid arthritis2, suggesting that fasting may be exploited as an immune-modulatory intervention. However, mechanisms underpinning anti-inflammatory effects of fasting remain poorly characte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95a3498d07e4be659e53da95745cb327
https://doi.org/10.1038/s42255-021-00356-0
https://doi.org/10.1038/s42255-021-00356-0
Autor:
Julián Candia, Yvonne Baumer, Michael N. Sack, Shahin Hassanzadeh, Tiffany M. Powell-Wiley, Komudi Singh, Kim Han, Foo Cheung, Jinguo Chen, Matthew J. Rodman, Mehdi Pirooznia, Katherine E. R. Stagliano, Rebecca D. Huffstutler
Publikováno v:
Nutrients
Volume 13
Issue 5
Nutrients, Vol 13, Iss 1492, p 1492 (2021)
Volume 13
Issue 5
Nutrients, Vol 13, Iss 1492, p 1492 (2021)
Intermittent fasting and fasting mimetic diets ameliorate inflammation. Similarly, serum extracted from fasted healthy and asthmatic subjects’ blunt inflammation in vitro, implicating serum components in this immunomodulation. To identify the prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e377a6c8bc9fcdd636a08bb45b9de12
Autor:
Michael N. Sack, Shahin Hassanzadeh, Kim Han, Fayaz Seifuddin, Ilker Tunc, Jennifer T Judy, Yun-Ching Chen, Mehdi Pirooznia, Komudi Singh
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Frontiers in Genetics
bioRxiv
Frontiers in Genetics
bioRxiv
Analyzing host transcriptional changes in response to SARS-CoV-2 infection will help delineate biological processes underlying viral pathogenesis. Comparison of expression profiles of lung cell lines A549 (infected with either SARS-CoV-2 (with ACE2 e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33ae0d7645dc382226aaabff964855cd
https://doi.org/10.3389/fgene.2021.599261
https://doi.org/10.3389/fgene.2021.599261
Autor:
Jing Wu, Komudi Singh, Amy Lin, Allison M. Meadows, Kaiyuan Wu, Vivian Shing, Maximilian Bley, Shahin Hassanzadeh, Rebecca D. Huffstutler, Mark S. Schmidt, Luz P. Blanco, Rong Tian, Charles Brenner, Mehdi Pirooznia, Mariana J. Kaplan, Michael N. Sack
Publikováno v:
The Journal of clinical investigation. 132(5)
BACKGROUNDFasting and NAD+-boosting compounds, including NAD+ precursor nicotinamide riboside (NR), confer antiinflammatory effects. However, the underlying mechanisms and therapeutic potential are incompletely defined.METHODSWe explored the underlyi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3fb017aaed704a327b05623f05326eb
https://pubmed.ncbi.nlm.nih.gov/35025762
https://pubmed.ncbi.nlm.nih.gov/35025762
Autor:
Steve O Winitsky, Thiru V Gopal, Shahin Hassanzadeh, Hiroshi Takahashi, Divina Gryder, Michael A Rogawski, Kazuyo Takeda, Zu X Yu, Yu H Xu, Neal D Epstein
Publikováno v:
PLoS Biology, Vol 3, Iss 4, p e87 (2005)
It has long been held as scientific fact that soon after birth, cardiomyocytes cease dividing, thus explaining the limited restoration of cardiac function after a heart attack. Recent demonstrations of cardiac myocyte differentiation observed in vitr
Externí odkaz:
https://doaj.org/article/47d3a49c068f4bd0bbd19656f2571872