Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Shahila Mehboob"'
Autor:
William D. Gregory, Shahila Mehboob Christie, John Shell, Georges J. Nahhas, Maharaj Singh, Wendy Mikkelson
Publikováno v:
Journal of Patient-Centered Research and Reviews, Vol 7, Iss 4, Pp 343-348 (2020)
We previously reported successful classification of breast cancer versus benign tissue using the Cole relaxation frequency measured on tissue excised during breast surgery as part of a study at two urban hospitals in the U.S. Midwest. Using that heal
Externí odkaz:
https://doaj.org/article/dad7193bba214bd1bea7fc1594263961
Autor:
Rajendra Goswami, Jasper Marc G. Bondoc, Paul R. Wheeler, Alireza Jafari, Trinidad Gonzalez, Shahila Mehboob, Farahnaz Movahedzadeh
Publikováno v:
ACS Omega, Vol 3, Iss 10, Pp 13876-13881 (2018)
Externí odkaz:
https://doaj.org/article/16d2b9019f154eedb5de92545e137e41
Autor:
Wendy Mikkelson, Georges J. Nahhas, Shahila Mehboob Christie, Maharaj Singh, John Shell, William D. Gregory
Publikováno v:
Journal of Patient-Centered Research and Reviews, Vol 7, Iss 4, Pp 343-348 (2020)
J Patient Cent Res Rev
J Patient Cent Res Rev
We previously reported successful classification of breast cancer versus benign tissue using the Cole relaxation frequency measured on tissue excised during breast surgery as part of a study at two urban hospitals in the U.S. Midwest. Using that heal
Autor:
Hyun Lee, Shahila Mehboob, Kirk E. Hevener, Bernard D. Santarsiero, Jesse A. Jones, Teuta Boci, Michael E. Johnson
Enoyl-acyl carrier protein (ACP) reductase II (FabK) is a critical rate-limiting enzyme in the bacterial type II fatty-acid synthesis (FAS II) pathway. FAS II pathway enzymes are markedly disparate from their mammalian analogs in the FAS I pathway in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8adfbfbdb3246761b0b94600938d0a9b
The enoyl-ACP reductase (FabI) enzyme is a well validated target for anti-staphylococcal drug discovery and development. With the goal of finding alternate therapeutics for drug-resistant strains of Staphylococcus aureus, such as methicillin-resistan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b3b2fedbb083a0c5a5db66ff25b5174
S. aureus and A. baumannii are among the ESKAPE pathogens that are increasingly difficult to treat due to the rise in the number of drug resistant strains. Novel therapeutics targeting these pathogens are much needed. The bacterial enoyl reductase (F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::787a392abcce178635146fa79703b00c
Autor:
Shahila Mehboob, Trinidad Gonzalez, Farahnaz Movahedzadeh, Paul R. Wheeler, Rajendra Goswami, Jasper Marc G. Bondoc, Alireza Jafari
Publikováno v:
ACS Omega, Vol 3, Iss 10, Pp 13876-13881 (2018)
Inositol monophosphatase (IMPase) is a crucial enzyme for the biosynthesis of phosphatidylinositol, an essential component in mycobacterial cell walls. IMPase A (ImpA) from Mycobacterium smegmatis is a bifunctional enzyme that also functions as a fru
Autor:
Shahila Mehboob, Arun K. Ghosh, Pin Chih Su, Michael E. Johnson, Tina Mistry, Robel Demissie, Leslie W.-M. Fung, Jinhong Ren
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 28:2074-2079
We have previously reported benzimidazole-based compounds to be potent inhibitors of FabI for Francisella tularensis (FtFabI), making them promising antimicrobial hits. Optically active enantiomers exhibit markedly differing affinities toward FtFabI.
Autor:
Ryan Patwell, Ram Samudrala, Maxwell Wiley Rutter, Cele Abad-Zapatero, Alexey Dementiev, Hiten J. Gutka, Shahila Mehboob, Farahnaz Movahedzadeh, Mashal M. Almutairi, Nina M. Wolf, Jasper Marc G. Bondoc
Publikováno v:
Acta Crystallogr F Struct Biol Commun
Acyl carrier proteins (ACPs) are important components in fatty-acid biosynthesis in prokaryotes. Rv0100 is predicted to be an essential ACP in Mycobacterium tuberculosis, the pathogen that is the causative agent of tuberculosis, and therefore has the
Autor:
Jasper Marc G. Bondoc, Hiten J. Gutka, Mashal M. Almutairi, Ryan Patwell, Maxwell W. Rutter, Nina M. Wolf, Ram Samudrala, Shahila Mehboob, Farahnaz Movahedzadeh
Publikováno v:
Acta Crystallographica. Section F, Structural Biology Communications
A correction is made to the article by Bondoc et al. [(2019). Acta Cryst. F75, 646–651].
The true identity of the protein found in the crystals reported by Bondoc et al. [(2019), Acta Cryst. F75, 646–651] is given.
The true identity of the protein found in the crystals reported by Bondoc et al. [(2019), Acta Cryst. F75, 646–651] is given.