Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Shahid, Mian"'
Autor:
Hugo Larose, Nina Prokoph, Jamie D. Matthews, Michaela Schlederer, Sandra Högler, Ali F. Alsulami, Stephen P. Ducray, Edem Nuglozeh, Feroze M.S. Fazaludeen, Ahmed Elmouna, Monica Ceccon, Luca Mologni, Carlo Gambacorti-Passerini, Gerald Hoefler, Cosimo Lobello, Sarka Pospisilova, Andrea Janikova, Wilhelm Woessmann, Christine Damm-Welk, Martin Zimmermann, Alina Federova, Andrea Malone, Owen Smith, Mariusz Wasik, Giorgio Inghirami, Laurence Lamant, Tom L. Blundell, Wolfram Klapper, Olaf Merkel, G.A. Amos Burke, Shahid Mian, Ibraheem Ashankyty, Lukas Kenner, Suzanne D. Turner
Publikováno v:
Haematologica, Vol 106, Iss 6 (2020)
Patients diagnosed with Anaplastic Large Cell Lymphoma (ALCL) are still treated with toxic multi-agent chemotherapy and as many as 25-50% of patients relapse. To understand disease pathology and to uncover novel targets for therapy, Whole-Exome Seque
Externí odkaz:
https://doaj.org/article/ac9c68b0d9e342ba919d333429ab5aaa
Autor:
Tim I. M. Malcolm, Patrick Villarese, Camilla J. Fairbairn, Laurence Lamant, Amélie Trinquand, C. Elizabeth Hook, G. A. Amos Burke, Laurence Brugières, Katherine Hughes, Dominique Payet, Olaf Merkel, Ana-Iris Schiefer, Ibraheem Ashankyty, Shahid Mian, Mariusz Wasik, Martin Turner, Lukas Kenner, Vahid Asnafi, Elizabeth Macintyre, Suzanne D. Turner
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Anaplastic large cell lymphoma is characterized by an NPM–ALK fusion but the cell of origin for this cancer is unclear. Here, the authors show that, in an NPM–ALK mouse model, the tumours likely arise from early thmyocytes and require an initial
Externí odkaz:
https://doaj.org/article/8a701b4d78ae4645840aae9ec06e39b7
Autor:
Gerald Hoefler, Jamie D. Matthews, Mariusz A. Wasik, Cosimo Lobello, Šárka Pospíšilová, Feroze Fazaludeen, Ahmed Elmouna, Monica Ceccon, Edem Nuglozeh, Martin Zimmermann, Michaela Schlederer, Hugo Larose, Christine Damm-Welk, Wilhelm Woessmann, Lukas Kenner, Giorgio Inghirami, Wolfram Klapper, Ibraheem Ashankyty, Olaf Merkel, Tom L. Blundell, Nina Prokoph, Shahid Mian, Luca Mologni, Laurence Lamant, Andrea Janíková, Andrea Malone, Alina Federova, G. A. Amos Burke, Suzanne D. Turner, Owen P. Smith, Carlo Gambacorti-Passerini, Sandra Högler, Ali F. Alsulami, Stephen P. Ducray
Publikováno v:
Haematologica
Patients diagnosed with anaplastic large cell lymphoma (ALCL) are still treated with toxic multi-agent chemotherapy and as many as 25-50% of patients relapse. To understand disease pathology and to uncover novel targets for therapy, we performed whol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bdffe2951211b6f92b06fdfe98cb310
http://hdl.handle.net/10281/336945
http://hdl.handle.net/10281/336945
Autor:
Ibraheem Ashankyty, Shahid Mian
Publikováno v:
Applied Molecular Biotechnology
Scopus-Elsevier
Scopus-Elsevier
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7823d7cfd28d38609a11ea0371af099a
https://doi.org/10.1201/b19543-19
https://doi.org/10.1201/b19543-19
Autor:
Michaela Schlederer, Suzanne D. Turner, Hugo Larose, Šárka Pospíšilová, Laurence Lamant, Ming-Qing Du, Ahmed Elmouna, Feroze Fazaludeen, Ibraheem Ashankyty, Wilhem Woessmann, Lukas Kenner, Alina Fedorova, Edem Nuglozeh, Olaf Merkel, Shahid Mian, Gerald Höfler, Christine Damm-Welk
Publikováno v:
Cancer Research. 78:1417-1417
In order to understand the biology of Anaplastic Large Cell Lymphoma (ALCL) and to develop biomarkers, we performed Whole-Exome Sequencing (WES) of DNA extracted from patient tumor samples (of at least 90% tumor cell content; n=31), and are exploring
Publikováno v:
ResearcherID
SummaryStatistical methodology for the analysis of proteomic mass spectrometry data is proposed using mixed effects models. Each high dimensional spectrum is represented by using a near orthogonal low dimensional representation with a basis of Gaussi
Autor:
Selman A. Ali, Amanda K. Miles, Robert C. Rees, Geng Li, Stephanie E. B. McArdle, Murrium Ahmad, Shahid Mian
Publikováno v:
Current Pharmaceutical Design. 11:3501-3509
During the last decade, a large number of human tumour antigens have been identified. These antigens are classified as tumour-specific shared antigens, tissue-specific differentiation antigens, overexpressed antigens, tumour antigens resulting from m
Autor:
Iris Schlenzka, Erika Parkinson, Lee Lancashire, Dirk Schadendorf, Shahid Mian, Robert C. Rees, Colin S. Creaser, Selma Ugurel, Graham Ball, Ian L. Dryden
Publikováno v:
Journal of Clinical Oncology. 23:5088-5093
Purpose Currently known serum biomarkers do not predict clinical outcome in melanoma. S100-β is widely established as a reliable prognostic indicator in patients with advanced metastatic disease but is of limited predictive value in tumor-free patie
Publikováno v:
Current Proteomics. 2:15-29
Artificial Neural Network (ANN) techniques are becoming increasing popular in many areas of the biological sciences for the analysis of complex data. Careful selection of key parameters when developing ANN models and algorithms is extremely important
Autor:
Shahid Mian, Stephanie E. B. McArdle, Geng Li, José M. Rojas, Matthew Bell, Robert C. Rees, Roger B. V. Horton, Selman A. Ali
Publikováno v:
Cancer Immunology, Immunotherapy. 54:243-253
Because of the central role of CD4(+) T cells in antitumour immunity, the identification of the MHC class II-restricted peptides to which CD4(+) T cells respond has become a priority of tumour immunologists. Here, we describe a strategy permitting us