Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Shaheen Khadem"'
Autor:
Mithun Santra, Yen Hsu, Shaheen Khadem, Sydney Radencic, Martha Funderburgh, Onkar Sawant, Deepinder Dhaliwal, Vishal Jhanji, Gary Yam
Publikováno v:
Bio-Protocol, Vol 14, Iss 18 (2024)
Corneal scarring, a significant cause of global blindness, results from various insults, including trauma, infections, and genetic disorders. The conventional treatment to replace scarred corneal tissues includes partial or full-thickness corneal tra
Externí odkaz:
https://doaj.org/article/5ed3d9d8edba4cae93d84b89f4f3301a
Autor:
Jeffrey L. Brodsky, Patrick G. Needham, Kasia Mikoluk, Pradeep Dhakarwal, Shaheen Khadem, Avin C. Snyder, Arohan R. Subramanya
Publikováno v:
Journal of Biological Chemistry. 286:43611-43621
The thiazide-sensitive NaCl cotransporter (NCC, SLC12A3) mediates salt reabsorption in the distal nephron of the kidney and is the target of thiazide diuretics, which are commonly prescribed to treat hypertension. Mutations in NCC also give rise to G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c333bebe8287db9a84bad505e9508067
https://doi.org/10.1074/jbc.m111.288928
https://doi.org/10.1074/jbc.m111.288928
Publikováno v:
Endocrinology. 149:3778-3788
Prostate cancer is the most commonly diagnosed and the second leading cause of cancer death in men. The androgens-androgen receptor signaling plays an important role in normal prostate development, as well as in prostatic diseases, such as benign hyp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69a0b9f688a1c46fe2a1011400364284
https://doi.org/10.1210/en.2007-1605
https://doi.org/10.1210/en.2007-1605
Autor:
Shikha Bhatia, Taira Wada, Songrong Ren, Haibiao Gong, Martin Angers, Hong Soon Kang, Ewa Ellis, Wen Xie, Anton M. Jetten, Shaheen Khadem, Stephen C. Strom
Publikováno v:
Molecular Pharmacology. 73:891-899
The retinoid-related orphan receptors (RORs) and liver X receptors (LXRs) were postulated to have distinct functions. RORs play a role in tissue development and circadian rhythm, whereas LXRs are sterol sensors that affect lipid homeostasis. In this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baa037a9f0feb06481fe9177cc1efd54
https://doi.org/10.1124/mol.107.040741
https://doi.org/10.1124/mol.107.040741
Autor:
Ankita Roy, Shaheen Khadem, Patrick G. Needham, Bridget F. Donnelly, Avin C. Snyder, Jeffrey L. Brodsky, Arohan R. Subramanya
Publikováno v:
The FASEB Journal. 27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a220cdf6a5cb13875dece1f491f6d170
https://doi.org/10.1096/fasebj.27.1_supplement.1210.1
https://doi.org/10.1096/fasebj.27.1_supplement.1210.1
Autor:
Shaheen Khadem, Patrick G. Needham, Ankita Roy, Avin C. Snyder, Bridget F. Donnelly, Jeffrey L. Brodsky, Arohan R. Subramanya
The thiazide-sensitive NaCl cotransporter (NCC) is the primary mediator of salt reabsorption in the distal convoluted tubule and is a key determinant of the blood pressure set point. Given its complex topology, NCC is inefficiently processed and pron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::938c62b0078abad911d1c1c92adcf248
https://europepmc.org/articles/PMC3642353/
https://europepmc.org/articles/PMC3642353/
Autor:
Shaheen Khadem, Yonggong Zhai, Taira Wada, Song Li, Wen Xie, Songrong Ren, Ramalinga Kuruba, Bin Zhang
Publikováno v:
Molecular pharmacology. 78(4)
The liver X receptor (LXR) and constitutive androstane receptor (CAR) are two nuclear receptors postulated to have distinct functions. LXR is a sterol sensor that promotes lipogenesis, whereas CAR is a xenosensor that controls xenobiotic responses. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26515e12e460c219f0bf8e09a5d75034
https://pubmed.ncbi.nlm.nih.gov/20592274
https://pubmed.ncbi.nlm.nih.gov/20592274
Autor:
Songrong Ren, Wen Xie, Shaheen Khadem, Archana Gangopadhyay, Yonggong Zhai, James A. Moser, Hirdesh Uppal
Publikováno v:
Hepatology (Baltimore, Md.). 47(4)
Gallstone disease is a hepatobiliary disorder due to biochemical imbalances in the gallbladder bile. In this report, we show that activation of nuclear receptor liver X receptor (LXR) sensitized mice to lithogenic diet–induced gallbladder cholester
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fb27b9df44666dcdbf2a7e2bac5fbbf
https://pubmed.ncbi.nlm.nih.gov/18318438
https://pubmed.ncbi.nlm.nih.gov/18318438