Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Shaheed Abdulhaqq"'
Autor:
Xiao L. Chang, Gabriela M. Webb, Helen L. Wu, Justin M. Greene, Shaheed Abdulhaqq, Katherine B. Bateman, Jason S. Reed, Cleiton Pessoa, Whitney C. Weber, Nicholas Maier, Glen M. Chew, Roxanne M. Gilbride, Lina Gao, Rebecca Agnor, Travis Giobbi, Jeffrey Torgerson, Don Siess, Nicole Burnett, Miranda Fischer, Oriene Shiel, Cassandra Moats, Bruce Patterson, Kush Dhody, Scott Kelly, Nader Pourhassan, Diogo M. Magnani, Jeremy Smedley, Benjamin N. Bimber, Nancy L. Haigwood, Scott G. Hansen, Timothy R. Brown, Lishomwa C. Ndhlovu, Jonah B. Sacha
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
CCR5 is a co-receptor for many transmitted HIV strains. Here, the authors show that biweekly injection of the CCR5-specific antibody Leronlimab protects rhesus macaques against infection following repeated intrarectal challenges of a CCR5-tropic SHIV
Externí odkaz:
https://doaj.org/article/e057d02dc1bf44278b9075dfe29c62e7
Autor:
Gabriela M Webb, Jhomary Molden, Kathleen Busman-Sahay, Shaheed Abdulhaqq, Helen L Wu, Whitney C Weber, Katherine B Bateman, Jason S Reed, Mina Northrup, Nicholas Maier, Shiho Tanaka, Lina Gao, Brianna Davey, Benjamin L Carpenter, Michael K Axthelm, Jeffrey J Stanton, Jeremy Smedley, Justin M Greene, Jeffrey T Safrit, Jacob D Estes, Pamela J Skinner, Jonah B Sacha
Publikováno v:
PLoS Pathogens, Vol 16, Iss 3, p e1008339 (2020)
Despite the success of antiretroviral therapy (ART) to halt viral replication and slow disease progression, this treatment is not curative and there remains an urgent need to develop approaches to clear the latent HIV reservoir. The human IL-15 super
Externí odkaz:
https://doaj.org/article/01a8e5f9eca0493ca269580027d9bf0e
Autor:
Lucy C. Walters, Karl Harlos, Simon Brackenridge, Daniel Rozbesky, Jordan R. Barrett, Vitul Jain, Thomas S. Walter, Chris A. O’Callaghan, Persephone Borrow, Mireille Toebes, Scott G. Hansen, Jonah B Sacha, Shaheed Abdulhaqq, Justin M. Greene, Klaus Früh, Emily Marshall, Louis J. Picker, E. Yvonne Jones, Andrew J. McMichael, Geraldine M. Gillespie
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Human leucocyte antigen E (HLA-E) directly engages NK cells but also presents antigen to CD8+ T cells. Here the authors show crystal structures of HLA-E in complex with peptides derived from HIV and Mycobacterium tuberculosis, and describe binding co
Externí odkaz:
https://doaj.org/article/c538b7f0bce048839998f3c2c728defd
Autor:
Benjamin J. Burwitz, Jochen M. Wettengel, Martin A. Mück-Häusl, Marc Ringelhan, Chunkyu Ko, Marvin M. Festag, Katherine B. Hammond, Mina Northrup, Benjamin N. Bimber, Thomas Jacob, Jason S. Reed, Reed Norris, Byung Park, Sven Moller-Tank, Knud Esser, Justin M. Greene, Helen L. Wu, Shaheed Abdulhaqq, Gabriela Webb, William F. Sutton, Alex Klug, Tonya Swanson, Alfred W. Legasse, Tania Q. Vu, Aravind Asokan, Nancy L. Haigwood, Ulrike Protzer, Jonah B. Sacha
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Hepatitis B virus (HBV) has a limited host range and current animal models can only recapitulate certain aspects of HBV replication. Here, the authors show that expression of the HBV receptor NTCP in macaques supports HBV replication in vivo, suggest
Externí odkaz:
https://doaj.org/article/2039d96647514d3c9a3deb587404ab5a
Autor:
Benjamin J. Burwitz, Helen L. Wu, Shaheed Abdulhaqq, Christine Shriver-Munsch, Tonya Swanson, Alfred W. Legasse, Katherine B. Hammond, Stephanie L. Junell, Jason S. Reed, Benjamin N. Bimber, Justin M. Greene, Gabriela M. Webb, Mina Northrup, Wolfram Laub, Paul Kievit, Rhonda MacAllister, Michael K. Axthelm, Rebecca Ducore, Anne Lewis, Lois M. A. Colgin, Theodore Hobbs, Lauren D. Martin, Betsy Ferguson, Charles R. Thomas Jr., Angela Panoskaltsis-Mortari, Gabrielle Meyers, Jeffrey J. Stanton, Richard T. Maziarz, Jonah B. Sacha
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Rhesus macaques are not ideal for studying response to allogeneic hematopoietic stem cell transplant (allo-HSCT) owing to complex MHC genetics that prevent full MHC-matching. Here the authors show that inbred Mauritian-origin cynomolgus macaques are
Externí odkaz:
https://doaj.org/article/594cf734e0da46758b10c7677bcfd4af
Autor:
James M Mullin, Katherine M Diguilio, Mary C Valenzano, Rachael Deis, Sunil Thomas, E Peter Zurbach, Shaheed Abdulhaqq, Luis J Montaner
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0170306 (2017)
Human semen has the potential to modulate the epithelial mucosal tissues it contacts, as seminal plasma (SP) is recognized to contain both pro- and anti-barrier components, yet its effects on epithelial barrier function are largely unknown. We addres
Externí odkaz:
https://doaj.org/article/f7eba496fdd641c1a93b4aa132a2a9fa
Autor:
Lucy C. Walters, Karl Harlos, Simon Brackenridge, Daniel Rozbesky, Jordan R. Barrett, Vitul Jain, Thomas S. Walter, Chris A. O’Callaghan, Persephone Borrow, Mireille Toebes, Scott G. Hansen, Jonah B. Sacha, Shaheed Abdulhaqq, Justin M. Greene, Klaus Früh, Emily Marshall, Louis J. Picker, E. Yvonne Jones, Andrew J. McMichael, Geraldine M. Gillespie
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
The original version of this Article contained an error in the spelling of the author Jonah B Sacha, which was incorrectly given as Jonah Sacha. These errors have now been corrected in both the PDF and HTML versions of the Article.
Externí odkaz:
https://doaj.org/article/8c01ab1930bc4f728c1dd9cf80ae2c91
Autor:
Amir Shanehsazzadeh, Sharrol Bachas, Matt McPartlon, George Kasun, John M. Sutton, Andrea K. Steiger, Richard Shuai, Christa Kohnert, Goran Rakocevic, Jahir M. Gutierrez, Chelsea Chung, Breanna K. Luton, Nicolas Diaz, Simon Levine, Julian Alverio, Bailey Knight, Macey Radach, Alex Morehead, Katherine Bateman, David A. Spencer, Zachary McDargh, Jovan Cejovic, Gaelin Kopec-Belliveau, Robel Haile, Edriss Yassine, Cailen McCloskey, Monica Natividad, Dalton Chapman, Joshua Bennett, Jubair Hossain, Abigail B. Ventura, Gustavo M. Canales, Muttappa Gowda, Kerianne A. Jackson, Jennifer T. Stanton, Marcin Ura, Luka Stojanovic, Engin Yapici, Katherine Moran, Rodante Caguiat, Amber Brown, Shaheed Abdulhaqq, Zheyuan Guo, Lillian R. Klug, Miles Gander, Joshua Meier
Generative artificial intelligence (AI) has the potential to greatly increase the speed, quality and controllability of antibody design. Traditionalde novoantibody discovery requires time and resource intensive screening of large immune or synthetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb137f0e3826b27c191afdefd0a76c0f
https://doi.org/10.1101/2023.01.08.523187
https://doi.org/10.1101/2023.01.08.523187
Autor:
Shaheed, Abdulhaqq, Abigail B, Ventura, Jason S, Reed, Arman A, Bashirova, Katherine B, Bateman, Eric, McDonald, Helen L, Wu, Justin M, Greene, John B, Schell, David, Morrow, Karin, Wisskirchen, Jeffrey N, Martin, Steven G, Deeks, Mary, Carrington, Ulrike, Protzer, Klaus, Früh, Scott G, Hansen, Louis J, Picker, Jonah B, Sacha, Benjamin N, Bimber
Publikováno v:
J Immunol
CD8(+) T cells are key mediators of antiviral and antitumor immunity. The isolation and study of antigen-specific CD8(+) T cells, as well as mapping of their MHC restriction, has practical importance to the study of disease and the development of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::00fd9d474c5abd34d091103a7e948fae
https://pubmed.ncbi.nlm.nih.gov/34810222
https://pubmed.ncbi.nlm.nih.gov/34810222
Autor:
Michael K. P. Liu, Geraldine M. Gillespie, Shaheed Abdulhaqq, Persephone Borrow, Klaus Früh, Simon J. Davis, Louis J. Picker, Prathiba Kurupati, Xiao-Ning Xu, M Rei, Andrew J. McMichael, Hongbing Yang, Hong Sun, Simon Brackenridge, Edward Jenkins, Vincenzo Cerundolo, Jonah B. Sacha, Weiwei Ma, Elena Brenna
Publikováno v:
Sci Immunol
Human leukocyte antigen-E (HLA-E) normally presents an HLA class Ia signal peptide to the NKG2A/C-CD94 regulatory receptors on natural killer (NK) cells and T cell subsets. Rhesus macaques immunized with a cytomegalovirus vectored simian immunodefici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6e01466ecc9dd17cf6efe89fcc1ca01
https://doi.org/10.1126/sciimmunol.abg1703
https://doi.org/10.1126/sciimmunol.abg1703