Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Shahanshah, Khan"'
Autor:
Shahanshah Khan, Youn-Tae Kwak, Lan Peng, Shuiqing Hu, Brandi L. Cantarel, Cheryl M. Lewis, Yunpeng Gao, Ram S. Mani, Thirumala-Devi Kanneganti, Hasan Zaki
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 19 (2023)
Colorectal cancer (CRC) at advanced stages is rarely curable, underscoring the importance of exploring the mechanism of CRC progression and invasion. NOD-like receptor family member NLRP12 was shown to suppress colorectal tumorigenesis, but the preci
Externí odkaz:
https://doaj.org/article/9a592545d1e544fd83a73d0b494e19c0
Publikováno v:
Journal of Biomedical Science, Vol 29, Iss 1, Pp 1-2 (2022)
Externí odkaz:
https://doaj.org/article/80e88afa53d04a1f90e6d9fdbef9431e
Autor:
Shahanshah Khan, Mahnoush S Shafiei, Christopher Longoria, John W Schoggins, Rashmin C Savani, Hasan Zaki
Publikováno v:
eLife, Vol 10 (2021)
The pathogenesis of COVID-19 is associated with a hyperinflammatory response; however, the precise mechanism of SARS-CoV-2-induced inflammation is poorly understood. Here, we investigated direct inflammatory functions of major structural proteins of
Externí odkaz:
https://doaj.org/article/a7321268367b4faf9f1255e5587dc319
Autor:
Shahanshah Khan, Hasan Zaki
Publikováno v:
Bio-Protocol, Vol 11, Iss 6 (2021)
The mucus layer in the gastrointestinal tract covers the apical surface of intestinal epithelial cells, protecting the mucosal tissue from enteric pathogen and commensal microorganisms. The mucus is primarily composed of glycosylated protein called m
Externí odkaz:
https://doaj.org/article/17ed6ee7ea0948258848744512a42f85
Autor:
SM Nashir Udden, Youn-Tae Kwak, Victoria Godfrey, Md Abdul Wadud Khan, Shahanshah Khan, Nicolas Loof, Lan Peng, Hao Zhu, Hasan Zaki
Publikováno v:
eLife, Vol 8 (2019)
Hepatocellular carcinoma (HCC) is a deadly human cancer associated with chronic inflammation. The cytosolic pathogen sensor NLRP12 has emerged as a negative regulator of inflammation, but its role in HCC is unknown. Here we investigated the role of N
Externí odkaz:
https://doaj.org/article/a5d0e0e2290e4ae8be3c82f5e74a1ee8
Autor:
NazreenKhanam, Siddiqui, Lubna, Parveen, Neha, Md NawajSarif, Md Safikul Islam, Shahanshah Khan, Sheikh Mohibul
This study uses the Normalised Difference Vegetation Index (NDVI) from 1992 to 2019 to examine the spatiotemporal patterns of vegetation dynamics in Varanasi, India. A popular remote sensing index for observing vegetation dynamics is NDVI. Landsat ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f5711f78ca1d33c2b000671e7bb7b42
Autor:
Shahanshah Khan, Sandeep Choudhary, Arun Kumar, Akanchha Mani Tripathi, Amit Alok, Jawahar Singh Adhikari, Moshahid Alam Rizvi, Nabo Kumar Chaudhury
Publikováno v:
Toxicology Reports, Vol 3, Iss , Pp 880-894 (2016)
The objective of this study was to evaluate organ-wise toxicological effects of sesamol and determine the LD50 cut-off value and GHS category following acute oral toxicity method OECD 423. An acute oral toxicity study was carried out in female C57BL/
Externí odkaz:
https://doaj.org/article/9e1b20be075147e49bb1c67a1bb376d8
Publikováno v:
In Vivo
Background/Aim: Melatonin (N-acetyl-5-methoxytryptamine), a chief secretory molecule of the pineal gland, has multiple properties, and numerous clinical investigations regarding its actions are in progress. This study investigated the radiomitigative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1846d73471101e07ab8c5a063562e368
https://doi.org/10.21873/invivo.12820
https://doi.org/10.21873/invivo.12820
Autor:
Neha, Parveen, Lubna, Siddiqui, Masood Ahsan, Siddiqui, Md Nawaj, Sarif, Md Safikul, Islam, Shahanshah, Khan, Nazreen, Khanam, Sk, Mohibul, Mohammad, Shariq
Publikováno v:
Environmental Science and Pollution Research.
Historically, industrialization has been a catalyst for built-up expansion generated by economic growth that transforms a landscape. In India, there is a paucity of exploration into how the economic shift transforms the cityscape. Therefore, the obje
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70237a2bbd10e0f2198102d3f8d9d8a4
https://doi.org/10.1007/s11356-022-23221-3
https://doi.org/10.1007/s11356-022-23221-3
Publikováno v:
Cancer Research. 83:2573-2573
NLRP12, a member of the NOD-like receptor family, has been characterized as a negative regulator of NF-κB and MAPK pathways in immune cells. We previously demonstrated that Nlrp12-deficient mice are highly susceptible to azoxymethane plus dextran so
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d9c26944ed5e7a2933e9f51f4235ace
https://doi.org/10.1158/1538-7445.am2023-2573
https://doi.org/10.1158/1538-7445.am2023-2573