Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Shahana A. Chumki"'
Publikováno v:
Molecular Biology of the Cell. 33
In vertebrates, epithelial cell-cell junctions must rapidly remodel to maintain barrier function as cells undergo dynamic shape-change events. Consequently, localized leaks sometimes arise within the tight junction (TJ) barrier, which are repaired by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9af7ea9485b2f59fa883fd1bce4988c8
https://doi.org/10.1091/mbc.e22-06-0205
https://doi.org/10.1091/mbc.e22-06-0205
Autor:
Saranyaraajan Varadarajan, Shahana A. Chumki, Rachel E. Stephenson, Eileen R. Misterovich, Jessica L. Wu, Claire E. Dudley, Ivan S. Erofeev, Andrew B. Goryachev, Ann L. Miller
Publikováno v:
Varadarajan, S, Chumki, S A, Stephenson, R, Misterovich, E R, Wu, J L, Dudley, C E, Erofeev, I, Goryachev, A B & Miller, A L 2022, ' Mechanosensitive calcium flashes promote sustained RhoA activation during tight junction remodeling ', Journal of Cell Biology, vol. 221, no. 4, e202105107 . https://doi.org/10.1083/jcb.202105107
Epithelial cell–cell junctions remodel in response to mechanical stimuli to maintain barrier function. Previously, we found that local leaks in tight junctions (TJs) are rapidly repaired by local, transient RhoA activation, termed “Rho flares,”
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12556182c9f4c6881bc3a7d7a2e041e5
https://doi.org/10.1083/jcb.202105107
https://doi.org/10.1083/jcb.202105107
Autor:
Jeanmarie D Mishler, Anne M. Casper, Ellen M Younkin, Mikael K Dunn, Shahana A Chumki, Thomas F Coates
Replication stress causes breaks at chromosomal locations called common fragile sites. Deletions causing loss of heterozygosity (LOH) in human tumors are strongly correlated with common fragile sites, but the role of gene conversion in LOH at fragile
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be1030ae5f92f0feb225fda192afd9a9
https://europepmc.org/articles/PMC5012379/
https://europepmc.org/articles/PMC5012379/
