Post-Exposure Anti-Ricin Treatment Protects Swine against Lethal Systemic and Pulmonary Exposures

Autor: Reut Falach, Anita Sapoznikov, Yentl Evgy, Moshe Aftalion, Arik Makovitzki, Avi Agami, Avishai Mimran, Elad Lerer, Alon Ben David, Ran Zichel, Shahaf Katalan, Amir Rosner, Tamar Sabo, Chanoch Kronman, Yoav Gal

Publikováno v: Toxins, Vol 12, Iss 6, p 354 (2020)

Ricin, a plant-derived toxin originating from the seeds of Ricinus communis (castor bean plant), is one of the most lethal toxins known. To date, there is no approved post-exposure therapy for ricin exposures. This work demonstrates for the first tim

Externí odkaz: https://doaj.org/article/8983b4478e4848209053341e5c0b4dfd

Biphasic cuirass ventilation is better than bag-valve mask ventilation for resuscitation following organophosphate poisoning

Autor: Ilan Gur, Shlomo Shapira, Shahaf Katalan, Amir Rosner, Shlomo Baranes, Ettie Grauer, Jacob Moran-Gilad, Arik Eisenkraft

Publikováno v: Toxicology Reports, Vol 2, Iss C, Pp 40-45 (2015)

Objective: Exposure to organophosphates (OP) may lead to a life threatening cholinergic crisis with death attributed to a rapidly progressive respiratory failure. In a toxicological mass casualty event involving organophosphate exposure, many of the

Externí odkaz: https://doaj.org/article/d451e39cd75f455ba23f1976a3d4bd4d

Placing CF

Autor: Sigal, Saphier, Shahaf, Katalan, Guy, Yacov, Anat, Berliner, Orit, Redy-Keisar, Gil, Fridkin, Lee, Ghindes-Azaria, Ishay, Columbus, Alexander, Pevzner, Eyal, Drug, Hagit, Prihed, Eytan, Gershonov, Yoav, Eichen, Shlomi, Elias, Galit, Parvari, Yossi, Zafrani

Publikováno v: Chemistry (Weinheim an der Bergstrasse, Germany).

Fluorine atoms play an important role in all branches of chemistry and accordingly, it is very important to study their unique and varied effects systematically, in particular, the structure-physicochemical properties relationship. The present study

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::942ea5441aafe3565baf4a76cee609a2
https://pubmed.ncbi.nlm.nih.gov/36374157

Intramuscular Exposure to a Lethal Dose of Ricin Toxin Leads to Endothelial Glycocalyx Shedding and Microvascular Flow Abnormality in Mice and Swine

Autor: Tamar Sabo, Shahaf Katalan, Anita Sapoznikov, Reut Falach, Chanoch Kronman, Yoav Gal, Moshe Aftalion, Yentl Evgy

Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 12345, p 12345 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 22

Ricin toxin isolated from the castor bean (Ricinus communis) is one of the most potent and lethal molecules known. While the pathophysiology and clinical consequences of ricin poisoning by the parenteral route, i.e., intramuscular penetration, have b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cf113fcc5b21637cdb3b333399fbb4a
https://www.mdpi.com/1422-0067/22/22/12345

Pathophysiological profile of awake and anesthetized pigs following systemic exposure to the highly lethal ricin toxin

Autor: Tamar Sabo, Yoav Gal, Shahaf Katalan, Anita Sapoznikov, Orr Goren, Amir Rosner, Chanoch Kronman, Reut Falach, Michael Goldvaser, Pinchas Halpern

Publikováno v: Clinical toxicology (Philadelphia, Pa.). 60(1)

Ricin, a plant-derived toxin originating from the seeds of Ricinus communis (castor bean plant), is one of the most lethal toxins known. To date, no in-depth study of systemic exposure to ricin in ...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b5dbdbea2b059008eec4d80a60577b6
https://pubmed.ncbi.nlm.nih.gov/34080504