Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Shahad Alsaiari"'
Autor:
Maria Kanelli, Neelkanth M. Bardhan, Morteza Sarmadi, Shahad Alsaiari, William T. Rothwell, Apurva Pardeshi, Dominique C. De Fiesta, Howard Mak, Virginia Spanoudaki, Nicole Henning, Jooli Han, Angela M. Belcher, Robert S. Langer, Ana Jaklenec
Publikováno v:
bioRxiv
Cancer therapy research is of high interest because of the persistence and mortality of the disease and the side effects of traditional therapeutic methods, while often multimodal treatments are necessary based on the patient’s needs. The developme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b13eb4e223daf50b902a9ce33fb0e9be
https://europepmc.org/articles/PMC10120681/
https://europepmc.org/articles/PMC10120681/
Autor:
Maria Kanelli, Neelkanth M. Bardhan, Morteza Sarmadi, Shahad Alsaiari, William Rothwell, Apurva Pardeshi, Angela M. Belcher, Ana Jaklenec, Robert S. Langer
Publikováno v:
Cancer Research. 83:820-820
The ability to treat tumors with high efficacy in a local microenvironment, while mitigating the side effects of systemic toxicity is an area of active investigation. Towards this goal, designing a minimally-invasive local therapeutic modality, with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4fe2e5593822d68b98f88017b0db8ae
https://doi.org/10.1158/1538-7445.am2023-820
https://doi.org/10.1158/1538-7445.am2023-820
Autor:
Rabih Halwani, Niveen M. Khashab, Mansour Aldehaiman, Shichao Sun, Somayah Qutub, Abdulaziz Almalik, Jasmeen S. Merzaban, Shahad Alsaiari, Mram Z. Alyami, Zhengwei Mao, Walaa S. Baslyman
Publikováno v:
Science advances. 7(4)
The major impediments to the implementation of cancer immunotherapies are the sustained immune effect and the targeted delivery of these therapeutics, as they have life-threatening adverse effects. In this work, biomimetic metal-organic frameworks [z
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97c993bc65da16b5aeef5d65a8982b11
https://pubmed.ncbi.nlm.nih.gov/33523955
https://pubmed.ncbi.nlm.nih.gov/33523955
Autor:
Somayah Qutub, Mram Z. Alyami, Jasmeen S. Merzaban, Rachid Sougrat, Fajr A. Aleisa, Yanyan Li, Niveen M. Khashab, Shahad Alsaiari
Publikováno v:
Journal of the American Chemical Society. 142(4)
Effective and cell-type-specific delivery of CRISPR/Cas9 gene editing elements remains a challenging open problem. Here we report the development of biomimetic cancer cell coated zeolitic imidazolate frameworks (ZIFs) for targeted and cell-specific d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f938c2ae7722687e5b3fb6e80af7aa3
https://pubmed.ncbi.nlm.nih.gov/31931564
https://pubmed.ncbi.nlm.nih.gov/31931564
Autor:
Jean-Olivier Durand, Sébastien Richeter, Marie Maynadier, Jonas G. Croissant, Laure Lichon, Makhlouf Boufatit, Marcel Garcia, Laurence Raehm, Chiara Mauriello Jimenez, Danielle Laurencin, Dina Aggad, Soraya Dib, Shahad Alsaiari, Magali Gary-Bobo, Niveen M. Khashab
Publikováno v:
ChemNanoMat. 4:46-51
Gemcitabine hydrochloride is an FDA-approved chemotherapeutic drug used in the treatment of various cancers. Several drawbacks of gemcitabine including its short in vivo half-life of 8-17 min associated with a rapid excretion by the kidneys and its p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d52847a619cdeebcfc2d25a9de0e223
https://doi.org/10.1002/cnma.201700264
https://doi.org/10.1002/cnma.201700264
Autor:
Lijo Francis, Mohammed A. Hammami, Niveen M. Khashab, Shahad Alsaiari, Noreddine Ghaffour, Jonas G. Croissant, Dalaver H. Anjum
Publikováno v:
ACS Applied Materials & Interfaces. 9:1737-1745
Engineering and scaling-up new materials for better water desalination are imperative to find alternative fresh water sources to meet future demands. Herein, the fabrication of hydrophobic poly(ether imide) composite nanofiber membranes doped with no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59d0b4214edad327d764e7ef98b23710
https://doi.org/10.1021/acsami.6b11167
https://doi.org/10.1021/acsami.6b11167
Autor:
Mohamed Eddaoudi, Abdulaziz Almalik, Karim Adil, Kholod Alamoudi, Aws Alshamsan, Sachin Patil, Niveen M. Khashab, Basem Moosa, Shahad Alsaiari
Publikováno v:
Chemistry - A European Journal. 22:13789-13793
Supramolecular self-assembly of histidine-capped-dialkoxy-anthracene (HDA) results in the formation of light-responsive nanostructures. Single-crystal X-ray diffraction analysis of HDA shows two types of hydrogen bonding. The first hydrogen bond is e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7df284ee158ee5d5f1c65bff836b2b24
https://doi.org/10.1002/chem.201601442
https://doi.org/10.1002/chem.201601442
Autor:
Niveen M. Khashab, Jie Lu, Fuyuhiko Tamanoi, Shahad Alsaiari, Lin Deng, Jeffrey I. Zink, Dingyuan Zhang, Jonas G. Croissant, Abdulaziz Almalik
Publikováno v:
Journal of Controlled Release. 229:183-191
Functional nanocarriers capable of transporting high drug contents without premature leakage and to controllably deliver several drugs are needed for better cancer treatments. To address this clinical need, gold cluster bovine serum albumin (AuNC@BSA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60ce24e6396d22821bffa0d18334acef
https://doi.org/10.1016/j.jconrel.2016.03.030
https://doi.org/10.1016/j.jconrel.2016.03.030
Publikováno v:
OpenNano, Vol 1, Iss C, Pp 36-45 (2016)
In spite of the huge advances in the area of synthetic carriers, their efficiency still poorly compares to natural vectors. Herein, we report the use of unmodified magnetotactic bacteria as a guidable delivery vehicle for DNA functionalized gold nano
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae90bba1f25b3af6f146d8ce6e4b27c3
http://www.sciencedirect.com/science/article/pii/S2352952016300093
http://www.sciencedirect.com/science/article/pii/S2352952016300093
Autor:
Nadir Bettache, Jonas G. Croissant, Vincent Chaleix, Michel Wong Chi Man, Mireille Rossel, Xavier Cattoën, Karen Tresfield, Niveen M. Khashab, Danielle Laurencin, Sébastien Richeter, Rachid Sougrat, Sébastien Clément, Jean-Olivier Durand, Chiara Mauriello Jimenez, Dina Aggad, Magali Gary-Bobo, Nicolas Cubedo, Erwan Oliviero, Marcel Garcia, Vincent Sol, Shahad Alsaiari, Marie Maynadier, Laurence Raehm, Manuel A. Roldan-Gutierrez, Clarence Charnay, Dorothée Berthomieu, Dalaver H. Anjum
Publikováno v:
Advanced Functional Materials
Advanced Functional Materials, Wiley, 2018, 28 (21), pp.1800235. ⟨10.1002/adfm.201800235⟩
Advanced Functional Materials, Wiley, 2018, 28 (21), pp.1800235. ⟨10.1002/adfm.201800235⟩
C.M.J. and D.A. contributed equally to this work. The grant “Chercheur d'Avenir Languedoc-Roussillon” attributed to M.G.-B. and the ANR nanoptPDT are gratefully acknowledged. The authors thank L. Lichon for technical assistance. DFT calculations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2183298d5a7c48a7825935be852419a1
https://hal.archives-ouvertes.fr/hal-01973302
https://hal.archives-ouvertes.fr/hal-01973302