Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Shah, Tariq K."'
Autor:
Basu, Saurajyoti, Brown, John E., Flannigan, G. Michael, Gill, Jason H., Loadman, Paul, Martin, Sandie W., Naylor, Brian, Puri, Rajiv, Scally, Andy J., Seargent, Jill M., Shah, Tariq K., Phillips, Roger M.
NAD(P)H:Quinone oxidoreductase-1 (NQO1) has been implicated in the bioreductive activation of the clinically active anticancer drug Mitomycin C (MMC) and a polymorphic variant of NQO1 which lacks functional enzyme activity (NQO1*2) has been linked wi
Externí odkaz:
http://hdl.handle.net/10454/6401
Autor:
Basu, Saurajyoti, Brown, John E., Flannigan, G. Michael, Gill, Jason H., Loadman, Paul, Naylor, Brian, Scally, Andy J., Seargent, Jill M., Shah, Tariq K., Puri, Rajiv, Phillips, Roger M., Martin, Sandie W.
A central theme within the concept of enzyme-directed bioreductive drug development is the potential to predict tumour response based on the profiling of enzymes involved in the bioreductive activation process. Mitomycin C (MMC) is the prototypical b
Externí odkaz:
http://hdl.handle.net/10454/6409
Autor:
Choudry, Guzanfar A., Hamilton Stewart, P.A., Double, John A., Krul, M.R.L., Naylor, Brian, Flannigan, G. Michael, Shah, Tariq K., Phillips, Roger M.
The indolequinone EO9 demonstrated good preclinical activity but failed to show clinical efficacy against a range of tumours following intravenous drug administration. A significant factor in EO9's failure in the clinic has been attributed to its rap
Externí odkaz:
http://hdl.handle.net/10454/3889
Autor:
Jain, Arun, Shah, Tariq K.
Publikováno v:
In European Urology June 2007 51(6):1680-1687
Publikováno v:
Journal of Urology; Jun1993, Vol. 149 Issue 6, p1431-1436, 6p
Publikováno v:
World Journal of Urology; March 1991, Vol. 9 Issue: 1 p7-11, 5p