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pro vyhledávání: '"Shagun Poddar"'
Publikováno v:
Cell Communication and Signaling, Vol 17, Iss 1, Pp 1-10 (2019)
Abstract Background miR-449a, an intronic miRNA, is highly down-regulated in the skeletal muscle during diabetes. Its levels are epigenetically regulated by altered acetylation/deacetylation on the promoter that it shares with its host gene, Cdc20b.
Externí odkaz:
https://doaj.org/article/9e5570e97427430c83616e577a6610be
Publikováno v:
Journal of Cellular Physiology. 232:2938-2945
Epigenetics refers to functionally relevant genomic changes that do not involve changes in the basic nucleotide sequence. Majorly, these are of two types: DNA methylation and histone modifications. Small RNA molecules called miRNAs are often thought
microRNAs (miRNAs) are small non-coding RNAs that regulate cellular processes by fine-tuning the levels of their target mRNAs. However, the regulatory elements determining cellular miRNA levels are not well studied. Previously, we had described an al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1455827c058d9001a9a3a846d8b4738c