Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Shafiq U Ahmed"'
Autor:
Cian J Lynch, Zahid H Shah, Simon J Allison, Shafiq U Ahmed, Jack Ford, Lorna J Warnock, Han Li, Manuel Serrano, Jo Milner
Publikováno v:
PLoS ONE, Vol 5, Iss 10, p e13502 (2010)
BackgroundThe NAD-dependent deacetylase SIRT1 is a nutrient-sensitive coordinator of stress-tolerance, multiple homeostatic processes and healthspan, while p53 is a stress-responsive transcription factor and our paramount tumour suppressor. Thus, SIR
Externí odkaz:
https://doaj.org/article/b83000647a4a4e2da18971e3da989111
Autor:
Anthony J. Chalmers, Ester M. Hammond, Katrina H. Stevenson, Lesley Gilmour, Mathew Neilson, Gabriela Kalna, Natividad Gomez-Roman, Ann Hedley, Kathreena M. Kurian, Karen Strathdee, Shaliny Ramachandran, Shafiq U. Ahmed, Ross D. Carruthers
Supplementary Figure S2 shows additional data obtained during aphidicolin studies detailed in Fig 1 and additional data detailing expression of genes associated with ongoing and stalled replication forks from figure 3.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::592337fe79979b5d93bc98d89016c0a7
https://doi.org/10.1158/0008-5472.22426309.v1
https://doi.org/10.1158/0008-5472.22426309.v1
Supplementary Figure S3 from PP2A Inhibitor PME-1 Drives Kinase Inhibitor Resistance in Glioma Cells
Autor:
Jukka Westermarck, Pirjo Laakkonen, Anthony J. Chalmers, John Eriksson, Hannu Haapasalo, Olayinka Raheem, Shafiq U. Ahmed, Emilia Peuhu, Mikael Jumppanen, Xi Qiao, Oxana V. Denisova, Amanpreet Kaur
Reactivation of specific PP2A complexes is required for PME-1 depletion-mediated synthetic lethality. Supplementary figure related to Figure 3.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a6e7fb9080ab3bef0ff7c52a8d89574
https://doi.org/10.1158/0008-5472.22413804
https://doi.org/10.1158/0008-5472.22413804
Autor:
Jukka Westermarck, Pirjo Laakkonen, Anthony J. Chalmers, John Eriksson, Hannu Haapasalo, Olayinka Raheem, Shafiq U. Ahmed, Emilia Peuhu, Mikael Jumppanen, Xi Qiao, Oxana V. Denisova, Amanpreet Kaur
Supplementary Figure legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b72f08ef31c3e574c926ed19dcb2bd1
https://doi.org/10.1158/0008-5472.22413792.v1
https://doi.org/10.1158/0008-5472.22413792.v1
Autor:
Anthony J. Chalmers, Ester M. Hammond, Katrina H. Stevenson, Lesley Gilmour, Mathew Neilson, Gabriela Kalna, Natividad Gomez-Roman, Ann Hedley, Kathreena M. Kurian, Karen Strathdee, Shaliny Ramachandran, Shafiq U. Ahmed, Ross D. Carruthers
Legends for supplementary figures and tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bed98444bceb7a56d38c300cfac58ce8
https://doi.org/10.1158/0008-5472.22426297.v1
https://doi.org/10.1158/0008-5472.22426297.v1
Autor:
Jukka Westermarck, Pirjo Laakkonen, Anthony J. Chalmers, John Eriksson, Hannu Haapasalo, Olayinka Raheem, Shafiq U. Ahmed, Emilia Peuhu, Mikael Jumppanen, Xi Qiao, Oxana V. Denisova, Amanpreet Kaur
List of indolocarbazole staurosporine analogues, their primary target proteins, and status in the clinical trials for the indicated diseases.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e520866adff69de42926553065dab57
https://doi.org/10.1158/0008-5472.22413783.v1
https://doi.org/10.1158/0008-5472.22413783.v1
Autor:
Jukka Westermarck, Pirjo Laakkonen, Anthony J. Chalmers, John Eriksson, Hannu Haapasalo, Olayinka Raheem, Shafiq U. Ahmed, Emilia Peuhu, Mikael Jumppanen, Xi Qiao, Oxana V. Denisova, Amanpreet Kaur
Supplementary Material and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18c6756cecf164a69f01c3e03bd16b87
https://doi.org/10.1158/0008-5472.22413789.v1
https://doi.org/10.1158/0008-5472.22413789.v1
Autor:
Anthony J. Chalmers, Ester M. Hammond, Katrina H. Stevenson, Lesley Gilmour, Mathew Neilson, Gabriela Kalna, Natividad Gomez-Roman, Ann Hedley, Kathreena M. Kurian, Karen Strathdee, Shaliny Ramachandran, Shafiq U. Ahmed, Ross D. Carruthers
Glioblastoma (GBM) is a lethal primary brain tumor characterized by treatment resistance and inevitable tumor recurrence, both of which are driven by a subpopulation of GBM cancer stem–like cells (GSC) with tumorigenic and self-renewal properties.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b1fc9bc98ebe46d33676dac136b7f18
https://doi.org/10.1158/0008-5472.c.6512293.v1
https://doi.org/10.1158/0008-5472.c.6512293.v1
Autor:
Jukka Westermarck, Pirjo Laakkonen, Anthony J. Chalmers, John Eriksson, Hannu Haapasalo, Olayinka Raheem, Shafiq U. Ahmed, Emilia Peuhu, Mikael Jumppanen, Xi Qiao, Oxana V. Denisova, Amanpreet Kaur
Glioblastoma multiforme lacks effective therapy options. Although deregulated kinase pathways are drivers of malignant progression in glioblastoma multiforme, glioma cells exhibit intrinsic resistance toward many kinase inhibitors, and the molecular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a59c88ce01e682ddfd69cdaa90e966de
https://doi.org/10.1158/0008-5472.c.6508818.v1
https://doi.org/10.1158/0008-5472.c.6508818.v1
Autor:
Anthony J. Chalmers, Ester M. Hammond, Katrina H. Stevenson, Lesley Gilmour, Mathew Neilson, Gabriela Kalna, Natividad Gomez-Roman, Ann Hedley, Kathreena M. Kurian, Karen Strathdee, Shaliny Ramachandran, Shafiq U. Ahmed, Ross D. Carruthers
Supplemental Table 1 Summary table of in vivo growth characteristics of E2, G7, R10, R15, R24, R9 and S2 GSC primary GBM cultures after intracranial injection in CD1 nude mice. Supplemental Table 2 List of primary antibodies utilised Supplemental Tab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::093c48101cf25dc7b8fbec8e9a9d2ad4
https://doi.org/10.1158/0008-5472.22426315
https://doi.org/10.1158/0008-5472.22426315