Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Shafinaz Hussein"'
Autor:
Chuanjiang Yu, Qiong Shen, Antony B. Holmes, Tongwei Mo, Anna Tosato, Rajesh Kumar Soni, Clarissa Corinaldesi, Sanjay Koul, Laura Pasqualucci, Shafinaz Hussein, Farhad Forouhar, Riccardo Dalla-Favera, Katia Basso
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract The myocyte enhancer factor 2B (MEF2B) transcription factor is frequently mutated in germinal center (GC)-derived B-cell lymphomas. Its ammino (N)-terminal mutations drive lymphomagenesis by escaping interaction with transcriptional represso
Externí odkaz:
https://doaj.org/article/6292144c17b347ab9eb2ceaf501c6457
Autor:
Juskaran Chadha, Shafinaz Hussein, Yougen Zhan, Jonah Shulman, Joshua Brody, Lynn Ratner, Amir Steinberg
Publikováno v:
International Journal of Hematology-Oncology and Stem Cell Research, Vol 13, Iss 2 (2019)
We report a case of a 76-year-old male with a history of relapsed and refractory diffuse large B-cell lymphoma (DLBCL).Our patient was initially treated with front line chemotherapy along with central nervous system (CNS) prophylaxis with complete re
Externí odkaz:
https://doaj.org/article/8192d80e08a44f4d8af906ad16ca2ba5
Publikováno v:
Case Reports in Hematology, Vol 2017 (2017)
Large granular lymphocytic (LGL) leukemia is a rare form of low grade leukemia characterized by large cytotoxic T cells or natural killer cells on morphological examination. Immunosuppressive therapy is employed as first-line therapy. Treatment optio
Externí odkaz:
https://doaj.org/article/998b03df2c7744b9a4ff89c9d8863f9d
Publikováno v:
Case Reports in Oncological Medicine, Vol 2017 (2017)
T cell histiocyte rich large B cell lymphoma (THRLBCL) is a rare subtype of non-Hodgkin’s lymphoma characterized by malignant B cells with reactive T lymphocytes. The pathophysiology is thought to involve cytokine-mediated evasion of T cell immune
Externí odkaz:
https://doaj.org/article/3ffedbd19bc74cf58ebe2d6c2c478642
Publikováno v:
Case Reports in Medicine, Vol 2015 (2015)
Sarcoidosis is an idiopathic multisystem disease characterized by the formation of noncaseating granulomas. It frequently presents with pulmonary infiltrates and bilateral hilar and mediastinal lymphadenopathy. Splenic involvement is common, but mass
Externí odkaz:
https://doaj.org/article/34e9ff4651a94326a8510134ba605f88
Autor:
Laura Pasqualucci, Riccardo Dalla-Favera, Shafinaz Hussein, Paul K. Brindle, Katia Basso, Tongwei Mo, Stefanie N. Meyer, Romain Duval, Antony B. Holmes, Sarah Nataraj, Victoria A. Wells, Sofija Vlasevska, Jiyuan Zhang
Supplementary Figure S1. CREBBP binds to GC-specific super-enhancers. Supplementary Figure S2. Crebbp and EP300 expression in the B cell subsets development in Crebbpfl/flCγ1-Cre and Crebbpfl/flCD19-Cre mice. Supplementary Figure S3. GSEA analysis o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a844675292f6ae70dedaa1c05d438345
https://doi.org/10.1158/2159-8290.22531622.v1
https://doi.org/10.1158/2159-8290.22531622.v1
Publikováno v:
The American Journal of dermatopathology. 44(8)
Granulomatous mycosis fungoides (GMF) harbors a worse prognosis compared with classic MF and remains a significant diagnostic dilemma. We analyzed clinicopathologic, immunophenotypic, and molecular characteristics of GMF to develop a diagnostic algor
Autor:
Bart Barlogie, Tayler van den Akker, Daniel Khaykin, Bruce Petersen, Siraj M. El Jamal, Jane Houldsworth, Yansheng Hao, Levi Machado, Shafinaz Hussein, Julie Teruya-Feldstein
Publikováno v:
Modern Pathology. 33:188-195
Genetics has played an important role in risk stratification for plasma cell myeloma patients, providing therapeutic guidance. In this study, we investigated the correlation of bone marrow morphologic features and genetic aberrations, including gene
Autor:
Shafinaz Hussein, Benjamin S. Glicksberg, Girish N. Nadkarni, Siraj M. El Jamal, Pallavi Khattar, Tayler van den Akker, Fahad Khan, Bridget K. Marcellino, Adolfo Firpo-Betancourt
Publikováno v:
Journal of Hematopathology
Autor:
Ranjan Upadhyay, Henry Marsh, Michael Yellin, Adeeb Rahman, Shafinaz Hussein, Joshua Brody, Dana Ostrowski, Yougen Zhan, Brian D. Brown, Andres M. Salazar, Linda Hammerich, Maxime Dhainaut, Thomas U. Marron, Miriam Merad, Judit Svensson-Arvelund
Publikováno v:
Nature Medicine. 25:814-824
Indolent non-Hodgkin’s lymphomas (iNHLs) are incurable with standard therapy and are poorly responsive to checkpoint blockade. Although lymphoma cells are efficiently killed by primed T cells, in vivo priming of anti-lymphoma T cells has been elusi