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Synthesis, biological evaluation and molecular modeling of novel thienopyrimidinone and triazolothienopyrimidinone derivatives as dual anti-inflammatory antimicrobial agents.

Autor: Bekhit AA; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Alexandria University, Alexandria 21521, Egypt. Electronic address: adnbekhit@pharmacy.alexu.edu.eg., Farghaly AM; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Alexandria University, Alexandria 21521, Egypt., Shafik RM; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Alexandria University, Alexandria 21521, Egypt., Elsemary MMA; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Alexandria University, Alexandria 21521, Egypt., Bekhit AEA; Department of Food Sciences, The University of Otago, Dunedin, New Zealand., Guemei AA; Department of Clinical Pharmacology, Faculty of Medicine, Alexandria University, Alexandria, Egypt., El-Shoukrofy MS; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Alexandria University, Alexandria 21521, Egypt., Ibrahim TM; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Kafrelsheikh University, Kafr El-Sheikh 33516, Egypt.

Publikováno v: Bioorganic chemistry [Bioorg Chem] 2018 Apr; Vol. 77, pp. 38-46. Date of Electronic Publication: 2018 Jan 04.

Synthesis of novel 2-[2-(substituted amino)phenethyl]-1 H-benzimidazoles; 3,4-dihydro and 1,2,3,4,-tetrahydropyrimido[1,6-a]-benzimidazoles as potential antiulcer agents.

Autor: Shafik RM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Alexandria, AR Egypt., El-Din SA, Eshba NH, El-Hawash SA, Desheesh MA, Abdel-Aty AS, Ashour HM

Publikováno v: Die Pharmazie [Pharmazie] 2004 Dec; Vol. 59 (12), pp. 899-905.

(+/-)alpha-Phenyl-beta-(3,4-dimethoxy)- and (+/-)alpha-phenyl-beta -(3,4-dihydroxy)phenethylamines: potential probes for nicotinic acetylcholine receptor-ion channel molecule from torpedo electric organ.

Autor: Shafik RM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Alexandria, Egypt., Soliman R, el-Hawash SA, el-Dardiry SA, Sherby S

Publikováno v: Journal of pharmaceutical sciences [J Pharm Sci] 1987 Oct; Vol. 76 (10), pp. 830-3.