Výsledky vyhledávání - "Shafaattalab, S"

Investigating inherited arrhythmias using hiPSC-derived cardiomyocytes

Autor: Arslanova A., Shafaattalab S., Lin E., Barszczewski T., Hove-Madsen L., Tibbits G.F.

Publikováno v: METHODS
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
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Fundamental to the functional behavior of cardiac muscle is that the cardiomyocytes are integrated as a functional syncytium. Disrupted electrical activity in the cardiac tissue can lead to serious complications including cardiac arrhythmias. Therefo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::d0e6aaf27c9f3fb6638c427854ea460d
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85109113404&doi=10.1016/j.ymeth.2021.06.015&partnerID=40&md5=5f4aeade79bc5e0c57b4cbb3451e1e70

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Atrial-specific hiPSC-derived cardiomyocytes in drug discovery and disease modeling

Autor: Gharanei M., Shafaattalab S., Sangha S., Gunawan M., Laksman Z., Hove-Madsen L., Tibbits G.F.

Publikováno v: METHODS
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname

The discovery and application of human-induced pluripotent stem cells (hiPSCs) have been instrumental in the investigation of the pathophysiology of cardiovascular diseases. Patient-specific hiPSCs can now be generated, genome-edited, and subsequentl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::7bd13e6f27e5bbd272ba6c8ef067070d
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85108550803&doi=10.1016/j.ymeth.2021.06.009&partnerID=40&md5=b63f1ac5968d8bf7fe7c6331175bf6ed

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Physiological phenotyping of the adult zebrafish heart

Autor: Lin, E, Shafaattalab, S, Gill, J, Al-Zeer, B, Craig, C, Lamothe, M, Rayani, K, Gunawan, M, Li, AY, Hove-Madsen, L, Tibbits, GF

Publikováno v: Marine Genomics
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname

The zebrafish has proven to be an excellent organism for manipulation of its genome from a long history of transcript down-regulation using morpholino oligimers to more recent genome editing tools such as CRISPR-Cas9. Early forward and reverse geneti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::4c11156cd470c0862bf6ba76ab48b0d9
https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=2068

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Akademický článek

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Zebrafish as a model of mammalian cardiac function: Optically mapping the interplay of temperature and rate on voltage and calcium dynamics

Autor: Rayani, K, Lin, E, Craig, C, Lamothe, M, Shafaattalab, S, Gunawan, M, Li, AY, Hove-Madsen, L, Tibbits, GF

Publikováno v: PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname

The zebrafish (Danio rerio) heart is a viable model of mammalian cardiovascular function due to similarities in heart rate, ultrastructure, and action potential morphology. Zebrafish are able to tolerate a wide range of naturally occurring temperatur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::2a62a00673af4142d818449b12c76903
https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=3309

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