Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Shady Allam"'
Publikováno v:
Saudi Pharmaceutical Journal, Vol 30, Iss 8, Pp 1170-1180 (2022)
Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related death. The major challenge in managing HCC is the resistance to chemotherapy. Leptin hormone is associated with different oncogenic pathways implicated in drug resistance.
Externí odkaz:
https://doaj.org/article/c2ba476938344ac3b1978a342abecd69
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 154, Iss , Pp 113562- (2022)
Background: Hypoxic microenvironment of colon cancer is associated with HIF-1α upregulation. HIF-1α response elements are responsible for autophagy induction that promotes tumor proliferation. Moreover, HIF-1α induces tumor cell proliferation via
Externí odkaz:
https://doaj.org/article/0830c587973c4e05b10f2d49fbebb5fc
Autor:
Amir Mohamed Abdelhamid, Mahmoud E. Youssef, Simona Cavalu, Gomaa Mostafa-Hedeab, Amal Youssef, Sara T. Elazab, Samar Ibrahim, Shady Allam, Rehab Mohamed Elgharabawy, Eman El-Ahwany, Noha A. Amin, Ahmed Shata, Osama A. Mohammed, Mahmoud Said Ibrahim Abdeldaiem, Ahmed Alhowail, Gaber El-Saber Batiha, Engy A. El-Mahmoudy, Maram Attia, Alaa Allam, Mona Y. Zaater, Mona M. Osman, Manar Nader, Aya Taha, Nada Abul Makarem, Sameh Saber
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Ulcerative colitis (UC), an inflammatory bowel disease, is a chronic condition of a multifaceted pathophysiology. The incidence of UC is increasing internationally. The current therapies for UC lack relative effectiveness and are associated with adve
Externí odkaz:
https://doaj.org/article/eb083941b36e443aad34270cf71f59db
Publikováno v:
Recent Patents on Anti-Cancer Drug Discovery. 18
Background: Solid tumors such as colon cancer are characterized by rapid and sustained cell proliferation, which ultimately results in hypoxia, induction of hypoxia-inducible factor-1α (HIF-1α), and activation of glycolysis to promote tumor surviva
Publikováno v:
Bulletin of Pharmaceutical Sciences. Assiut.
Autor:
Shady Allam, Elsayed G.E. Elsakka, Ahmed Ismail, Ahmed S. Doghish, Amr Mohamed Yehia, Mohamed A. Elkady, Hamada Ahmed Mokhlis, Sara M. Sayed, Adel I. Abd Elaziz, Abdullah A. Hashish, Mona M. Amin, Rehab Mohamed El Shahat, Osama A. Mohammed
Publikováno v:
Life Sciences. 323:121697
Autor:
Simona Cavalu, Hossam Sharaf, Sameh Saber, Mahmoud E. Youssef, Amir Mohamed Abdelhamid, Ahmed A. E. Mourad, Samar Ibrahim, Shady Allam, Rehab Mohamed Elgharabawy, Eman El‐Ahwany, Noha A. Amin, Ahmed Shata, Mai Eldegla, Marina Atef, Maii Aboraya, Mayar Mohamed, Niera Anz, Dina Abd Elmotelb, Fayrouz Gabr, Dalia Elzablawy, Menna Hamada, Amr Yehia, Dalia Osama, Osama A. Mohammed
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental BiologyREFERENCES. 36(9)
Ulcerative colitis (UC) is a chronic inflammatory bowel disease of unknown etiology that increases the risk of developing colorectal cancer and imposes a lifelong healthcare burden on millions of patients worldwide. Current treatment strategies are a
Publikováno v:
Life sciences. 296
Investigating the impact of 17β estradiol (E2) and its endogenous non-hormonal metabolite 2-methoxyestradiol (2ME) on renal ischemia-reperfusion (RIR) induced kidney injury in ovariectomized (OVX) rats and the role of catechol-O-methyltransferase (C
Autor:
Montaser Sh. A. Shaykoon, Bakheet E. M. Elsadek, Mahmoud M. A. Elsayed, Mahmoud Mostafa, Ahmed R. H. Ahmed, Eman Alaaeldin, Hatem A. Sarhan, Shady Allam
Publikováno v:
International Journal of Nanomedicine. 14:8445-8467
Purpose Over the past 30 years, no consistent survival benefits have been recorded for anticancer agents of advanced hepatocellular carcinoma (HCC), except for the multikinase inhibitor sorafenib (Nexavar®), which clinically achieves only ~3 months
Publikováno v:
International Journal of Cancer and Biomedical Research.
Background: Bronchial asthma is an inflammatory lung disease characterized by hyper-responsiveness and bronchoconstriction. Beta2 agonists are bronchodilator drugs that possess anti-inflammatory properties. Aim: The present study aimed to investigate