Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Shadrack M, Mutuku"'
Autor:
Jesse A. Michael, Shadrack M. Mutuku, Boris Ucur, Tassiani Sarretto, Alan T. Maccarone, Marcel Niehaus, Adam J. Trevitt, Shane R. Ellis
Publikováno v:
Analytical Chemistry. 94:17494-17503
Here we report the development and optimization of a mass spectrometry imaging (MSI) platform that combines an atmospheric-pressure matrix-assisted laser desorption/ionization platform with plasma postionization (AP-MALDI-PPI) and trapped ion mobilit
Autor:
Johannes V. Swinnen, Margaret M. Centenera, Lisa G. Horvath, Wayne D. Tilley, David J. Lynn, Marten F. Snel, Paul J. Trim, Luke A. Selth, Zeyad D. Nassar, Etienne Waelkens, Rita Derua, Thomas Gevaert, James G. Kench, Jurgen Stahl, Rajdeep Das, Katarzyna Bloch, Frank Vanderhoydonc, Jonas Dehairs, Max Moldovan, David Waltregny, Muralidhararao Bagadi, Xander Spotbeen, Shadrack M. Mutuku, Swati Irani, Andrew D. Vincent, Jelle Machiels, Chui Yan Mah, Lisa M. Butler
Results of lipid association analyses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cf809a0c68942e4c775b65a6f0f125b
https://doi.org/10.1158/0008-5472.22428964.v1
https://doi.org/10.1158/0008-5472.22428964.v1
Autor:
Johannes V. Swinnen, Margaret M. Centenera, Lisa G. Horvath, Wayne D. Tilley, David J. Lynn, Marten F. Snel, Paul J. Trim, Luke A. Selth, Zeyad D. Nassar, Etienne Waelkens, Rita Derua, Thomas Gevaert, James G. Kench, Jurgen Stahl, Rajdeep Das, Katarzyna Bloch, Frank Vanderhoydonc, Jonas Dehairs, Max Moldovan, David Waltregny, Muralidhararao Bagadi, Xander Spotbeen, Shadrack M. Mutuku, Swati Irani, Andrew D. Vincent, Jelle Machiels, Chui Yan Mah, Lisa M. Butler
Supplementary Figures S1-S6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55b89972cab90e3a0c804a03e7cfba5a
https://doi.org/10.1158/0008-5472.22428970
https://doi.org/10.1158/0008-5472.22428970
Autor:
Johannes V. Swinnen, Margaret M. Centenera, Lisa G. Horvath, Wayne D. Tilley, David J. Lynn, Marten F. Snel, Paul J. Trim, Luke A. Selth, Zeyad D. Nassar, Etienne Waelkens, Rita Derua, Thomas Gevaert, James G. Kench, Jurgen Stahl, Rajdeep Das, Katarzyna Bloch, Frank Vanderhoydonc, Jonas Dehairs, Max Moldovan, David Waltregny, Muralidhararao Bagadi, Xander Spotbeen, Shadrack M. Mutuku, Swati Irani, Andrew D. Vincent, Jelle Machiels, Chui Yan Mah, Lisa M. Butler
Patient and sample clinical characteristics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95c0430a676fbe050304ef599888f8ec
https://doi.org/10.1158/0008-5472.22428967
https://doi.org/10.1158/0008-5472.22428967
Autor:
Johannes V. Swinnen, Margaret M. Centenera, Lisa G. Horvath, Wayne D. Tilley, David J. Lynn, Marten F. Snel, Paul J. Trim, Luke A. Selth, Zeyad D. Nassar, Etienne Waelkens, Rita Derua, Thomas Gevaert, James G. Kench, Jurgen Stahl, Rajdeep Das, Katarzyna Bloch, Frank Vanderhoydonc, Jonas Dehairs, Max Moldovan, David Waltregny, Muralidhararao Bagadi, Xander Spotbeen, Shadrack M. Mutuku, Swati Irani, Andrew D. Vincent, Jelle Machiels, Chui Yan Mah, Lisa M. Butler
Dysregulated lipid metabolism is a prominent feature of prostate cancer that is driven by androgen receptor (AR) signaling. Here we used quantitative mass spectrometry to define the “lipidome” in prostate tumors with matched benign tissues (n = 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::810351ce69edbad864fa28fec84a8835
https://doi.org/10.1158/0008-5472.c.6513199.v1
https://doi.org/10.1158/0008-5472.c.6513199.v1
Autor:
Patience, Castleton, Prabin, Gyawali, Nicola, Mathews, Shadrack M, Mutuku, David J, Sharkey, Nicole O, McPherson
Publikováno v:
Andrology.
Oxidative stress in semen contributes up to 80% of all infertility diagnosis. Diagnostics to measure oxidative stress in semen was recently added to the 6To determine the natural fluctuations in semen redox indicators (MiOXSYSTotal, 118 repeat semen
Autor:
David Waltregny, Wayne D. Tilley, Jurgen Stahl, James G. Kench, Shadrack M. Mutuku, Zeyad D. Nassar, Marten F. Snel, Jelle Machiels, Rita Derua, Johannes V. Swinnen, Rajdeep Das, Xander Spotbeen, Luke A. Selth, Swati Irani, Paul J. Trim, Frank Vanderhoydonc, Thomas Gevaert, Chui Yan Mah, Andrew D. Vincent, Lisa G. Horvath, Etienne Waelkens, Margaret M. Centenera, Lisa M. Butler, Jonas Dehairs, David J. Lynn, Muralidhararao Bagadi, Max Moldovan, Katarzyna Bloch
Dysregulated lipid metabolism is a prominent feature of prostate cancer that is driven by androgen receptor (AR) signaling. Here we used quantitative mass spectrometry to define the “lipidome” in prostate tumors with matched benign tissues (n = 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d25e668067bd02ba18babf88cc98c36
https://lirias.kuleuven.be/handle/123456789/682357
https://lirias.kuleuven.be/handle/123456789/682357
Autor:
Shane R. Ellis, Shadrack M. Mutuku
Publikováno v:
MALDI Mass Spectrometry Imaging
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bcac3b36a5c64d734c982e533eaa08d1
https://doi.org/10.1039/9781839165191-00157
https://doi.org/10.1039/9781839165191-00157
Autor:
Zeyad D. Nassar, Chui Yan Mah, Wayne D. Tilley, Jurgen Stahl, Thomas Gevaert, David Waltregny, David J. Lynn, Margaret M. Centenera, Lisa M. Butler, Paul J. Trim, Shadrack M. Mutuku, James G. Kench, Lisa G. Horvath, Muralidhararao Bagadi, Johannes V. Swinnen, Max Moldovan, Rajdeep Das, Rita Derua, Xander Spotbeen, Katarzyna Bloch, Swati Irani, Frank Vanderhoydonc, Marten F. Snel, Jelle Machiels, Luke A. Selth, Jonas Dehairs, Andrew D. Vincent, Etienne Waelkens
Dysregulated lipid metabolism is a prominent feature of prostate cancer that is driven by androgen receptor (AR) signaling. Herein, we used quantitative mass spectrometry to define the “lipidome” in prostate tumors with matched benign tissues (n=
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4fde32835cc294f7e6d9ed577abc6bd
https://doi.org/10.1101/2020.10.27.356634
https://doi.org/10.1101/2020.10.27.356634
Autor:
Swati Irani, Shadrack M. Mutuku, Paul J. Trim, Margaret M. Centenera, Lisa M. Butler, Douglas A. Brooks, Bala K. Prabhala, Jurgen Stahl, Kayla L. Bremert, Marten F. Snel, Jessica M. Logan
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Mutuku, S M, Trim, P J, Prabhala, B K, Irani, S, Bremert, K L, Logan, J M, Brooks, D A, Stahl, J, Centenera, M M, Snel, M F & Butler, L M 2019, ' Evaluation of Small Molecule Drug Uptake in Patient-Derived Prostate Cancer Explants by Mass Spectrometry ', Scientific Reports, vol. 9, no. 1, 15008 . https://doi.org/10.1038/s41598-019-51549-3
Scientific Reports
Mutuku, S M, Trim, P J, Prabhala, B K, Irani, S, Bremert, K L, Logan, J M, Brooks, D A, Stahl, J, Centenera, M M, Snel, M F & Butler, L M 2019, ' Evaluation of Small Molecule Drug Uptake in Patient-Derived Prostate Cancer Explants by Mass Spectrometry ', Scientific Reports, vol. 9, no. 1, 15008 . https://doi.org/10.1038/s41598-019-51549-3
Scientific Reports
Patient-derived explant (PDE) culture of solid tumors is increasingly being applied to preclinical evaluation of novel therapeutics and for biomarker discovery. In this technique, treatments are added to culture medium and penetrate the tissue via a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5cc3e7aa307d58acdfb0941d30eae46
https://hdl.handle.net/11541.2/139813
https://hdl.handle.net/11541.2/139813