Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Shadi Zabad"'
Autor:
Luke Anderson-Trocmé, Dominic Nelson, Shadi Zabad, Alex Diaz-Papkovich, Ivan Kryukov, Nikolas Baya, Mathilde Touvier, Ben Jeffery, Christian Dina, Hélène Vézina, Jerome Kelleher, Simon Gravel
Publikováno v:
Science. 380:849-855
Population genetic models only provide coarse representations of real-world ancestry. We used a pedigree compiled from 4 million parish records and genotype data from 2276 French and 20,451 French Canadian individuals to finely model and trace French
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a63eeab1b90f417748a333252db659f
https://doi.org/10.1126/science.add5300
https://doi.org/10.1126/science.add5300
The recent proliferation of large scale genome-wide association studies (GWASs) has motivated the development of statistical methods for phenotype prediction using single nucleotide polymorphism (SNP) array data. These polygenic risk score (PRS) meth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7f067e07e8f7ecc993f0f9b3ff9f401
https://doi.org/10.1101/2022.05.10.491396
https://doi.org/10.1101/2022.05.10.491396
Autor:
Jaak Raudsepp, Karyna Kravchenko, Paola S. Llinás santos, Constance J. Jeffery, Annabel Shen, Nina Rivera, Maheen Hassan, Stephanie M. Gomez de Jesus, Chang Chen, Sophia Shen, Haipeng Liu, Mariia Mikhova, Emily Rowin, Shadi Zabad, Bryan Horan, Sophia Ketterer, Erin Navas
Publikováno v:
Nucleic Acids Research
MoonProt 3.0 (http://moonlightingproteins.org) is an updated open-access database storing expert-curated annotations for moonlighting proteins. Moonlighting proteins have two or more physiologically relevant distinct biochemical or biophysical functi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4304e1790d8bfc0494474f87074190fd
https://doi.org/10.1093/nar/gkaa1101
https://doi.org/10.1093/nar/gkaa1101
Publikováno v:
Genetic epidemiologyREFERENCES. 45(6)
Linkage-Disequilibrium Score Regression (LDSC) is a popular framework for analyzing GWAS summary statistics that allows for estimating SNP heritability, confounding, and functional enrichment of genetic variants with different annotations. Recent wor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e3b53c95ab1c7fdc3615e50c1de9216
https://pubmed.ncbi.nlm.nih.gov/34157784
https://pubmed.ncbi.nlm.nih.gov/34157784
Autor:
Shadi Zabad, Alan M. Moses
We study the evolution of quantitative molecular traits in the absence of selection. Using Felsenstein’s 1981 DNA substitution model, we predict a linear restoring force on the mean of an additive phenotype. Remarkably, the mean dynamics are indepe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b6e8449de3576178b7d27b222926472
https://doi.org/10.1101/2020.10.26.355438
https://doi.org/10.1101/2020.10.26.355438
Publikováno v:
Nucleic Acids Research
MoonProt 2.0 (http://moonlightingproteins.org) is an updated, comprehensive and open-access database storing expert-curated annotations for moonlighting proteins. Moonlighting proteins contain two or more physiologically relevant distinct functions p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48ef53aa930b44aacc6ee1e567840f50
https://pubmed.ncbi.nlm.nih.gov/29126295
https://pubmed.ncbi.nlm.nih.gov/29126295
Autor:
Shadi Zabad, Constance J. Jeffery, Chang Chen, Haipeng Liu, Jagravi Thakkar, Bansi Patel, Grant L. Zwicke, Vaishak Amblee, Tanu Mathur, Mathew Mani
Publikováno v:
Nucleic Acids Research
Moonlighting proteins comprise a class of multifunctional proteins in which a single polypeptide chain performs multiple biochemical functions that are not due to gene fusions, multiple RNA splice variants or pleiotropic effects. The known moonlighti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84e5d1b08a11d2ddbf4b7c90552cac62
https://doi.org/10.1096/fasebj.29.1_supplement.567.10
https://doi.org/10.1096/fasebj.29.1_supplement.567.10