Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Shadi Salloum"'
Autor:
Volney A. Spalding, Brian A. Fellenstein, James Ahodantin, Andre J. Jeyarajan, Yongtao Wang, Sanjoy K. Khan, Min Xu, Wenyu Lin, Nadia Alatrakchi, Lishan Su, Raymond T. Chung, Shadi Salloum
Publikováno v:
JHEP Reports, Vol 6, Iss 11, Pp 101163- (2024)
Background & Aims: HIV accelerates liver fibrosis attributable to multiple etiologies, including HCV, HBV, and steatotic liver disease. Evidence also suggests that HIV infection itself is associated with liver fibrogenesis. Recent studies have implic
Externí odkaz:
https://doaj.org/article/e74f747da88140ff9226da0f424d461b
Autor:
Myung‐Ho Kim, Mi‐Young Kim, Shadi Salloum, Tongqi Qian, Lai Ping Wong, Min Xu, Yoojin Lee, Stuti G. Shroff, Ruslan I. Sadreyev, Kathleen E. Corey, Thomas F. Baumert, Yujin Hoshida, Raymond T. Chung
Publikováno v:
Hepatology Communications, Vol 6, Iss 9, Pp 2581-2593 (2022)
Abstract Lipophilic but not hydrophilic statins have been shown to be associated with reduced risk for hepatocellular carcinoma (HCC) in patients with chronic viral hepatitis. We investigated differential actions of lipophilic and hydrophilic statins
Externí odkaz:
https://doaj.org/article/40cf497b78c3424da7b5b2059d8f1041
Autor:
Mozhdeh Sojoodi, Derek J. Erstad, Stephen C. Barrett, Shadi Salloum, Shijia Zhu, Tongqi Qian, Selene Colon, Eric M. Gale, Veronica Clavijo Jordan, Yongtao Wang, Shen Li, Bahar Ataeinia, Sasan Jalilifiroozinezhad, Michael Lanuti, Lawrence Zukerberg, Peter Caravan, Yujin Hoshida, Raymond T. Chung, Gautam Bhave, Georg M. Lauer, Bryan C. Fuchs, Kenneth K. Tanabe
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 5, Pp 1483-1509 (2022)
Background & Aims: During liver fibrosis, tissue repair mechanisms replace necrotic tissue with highly stabilized extracellular matrix proteins. Extracellular matrix stabilization influences the speed of tissue recovery. Here, we studied the expressi
Externí odkaz:
https://doaj.org/article/6ba526f7c87641729036d4c0c5724ed3
Autor:
Shadi Salloum, Andre J. Jeyarajan, Annie J. Kruger, Jacinta A. Holmes, Tuo Shao, Mozhdeh Sojoodi, Myung-Ho Kim, Zhu Zhuo, Stuti G. Shroff, Andrew Kassa, Kathleen E. Corey, Sanjoy K. Khan, Wenyu Lin, Nadia Alatrakchi, Esperance A.K. Schaefer, Raymond T. Chung
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 4, Pp 1297-1310 (2021)
Background & Aims: Patients with simple steatosis (SS) and nonalcoholic steatohepatitis can develop progressive liver fibrosis, which is associated with liver-related mortality. The mechanisms contributing to liver fibrosis development in SS, however
Externí odkaz:
https://doaj.org/article/1759109dd3a24be2821aee4ddafd1cc4
Publikováno v:
PLoS Pathogens, Vol 9, Iss 8, p e1003513 (2013)
Hepatitis C virus (HCV) is a single-stranded RNA virus that replicates on endoplasmic reticulum-derived membranes. HCV particle assembly is dependent on the association of core protein with cellular lipid droplets (LDs). However, it remains uncertain
Externí odkaz:
https://doaj.org/article/c039d6d8d7fc4f3b81e8cc42b7918ad6
Autor:
Andrew W Tai, Shadi Salloum
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26300 (2011)
Hepatitis C virus (HCV), like other positive-sense RNA viruses, replicates on an altered host membrane compartment that has been called the "membranous web." The mechanisms by which the membranous web are formed from cellular membranes are poorly und
Externí odkaz:
https://doaj.org/article/a8116a36d0534add9e19d344dbe69a65
Autor:
Akif Altinbas, Jacinta A Holmes, Shadi Salloum, Anna Lidofsky, Nadia Alatrakchi, Ma Somsouk, Peter Hunt, Steven Deeks, Kara W Chew, Georg Lauer, Annie Kruger, Wenyu Lin, Raymond T Chung
Publikováno v:
Biomarkers in Medicine. 16:839-846
Background: Lysil oxidase like enzyme-2 (LOXL-2) and TNC-C play important roles in organ fibrosis. We assessed circulating LOXL-2 and TNC-C levels and their relationship to fibrosis severity in HIV- and/or HCV-infected individuals. Methods: Healthy c
Autor:
Ang Cui, Bo Li, Michael S. Wallace, Anna L.K. Gonye, Christopher Oetheimer, Hailey Patel, Pierre Tonnerre, Jacinta A. Holmes, David Lieb, Brianna S. Yao, Aileen Ma, Kela Roberts, Marcos Damasio, Jonathan H. Chen, Daphnee Piou, Charles Carlton-Smith, Joelle Brown, Ravi Mylvaganam, Jeremy Man Hon Fung, Moshe Sade-Feldman, Jasneet Aneja, Jenna Gustafson, Eliana T. Epstein, Shadi Salloum, Cynthia Brisac, Ashraf Thabet, Arthur Y. Kim, Georg M. Lauer, Nir Hacohen, Raymond T. Chung, Nadia Alatrakchi
Publikováno v:
Journal of Hepatology.
Autor:
Wenting Li, Xiaoqiong Duan, Chuanlong Zhu, Xiao Liu, Andre J. Jeyarajan, Min Xu, Zeng Tu, Qiuju Sheng, Dong Chen, Chuanwu Zhu, Tuo Shao, Zhimeng Cheng, Shadi Salloum, Esperance A. Schaefer, Annie J. Kruger, Jacinta A. Holmes, Raymond T. Chung, Wenyu Lin
Publikováno v:
J Immunol
Hepatitis B virus (HBV)/hepatitis C virus (HCV) coinfection accelerates liver fibrosis progression compared with HBV or HCV monoinfection. Octamer binding transcription factor 4 (OCT4) and Nanog are direct targets of the profibrogenic TGF-β1 signali
Autor:
Mozhdeh Sojoodi, Stephen C. Barrett, Derek J. Erstad, Veronica Clavijo Jordan, Eric M. Gale, Shadi Salloum, Yongtao Wang, Michael Lanuti, Lawrence Zukerberg, Peter Caravan, Georg M. Lauer, Kenneth K. Tanabe
Publikováno v:
Cancer Research. 83:LB278-LB278
Introduction: Interleukin 12 (IL-12) is an important bridge between the innate and adaptive immune systems. It is mainly produced by macrophages and can bind to its receptor (IL12R) on T cells. It affects several aspects of T cell activation, includi