Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Shadi Jafari"'
Publikováno v:
PLoS Biology, Vol 19, Iss 4, p e3001101 (2021)
Here, we reveal that the regulation of Drosophila odorant receptor (OR) expression during the pupal stage is permissive and imprecise. We found that directly after hatching an OR feedback mechanism both directs and refines OR expression. We demonstra
Externí odkaz:
https://doaj.org/article/0d551a66230c4d8393517c55fde8cf12
Publikováno v:
PLoS Computational Biology, Vol 15, Iss 1, p e1006709 (2019)
Complex eukaryotic promoters normally contain multiple cis-regulatory sequences for different transcription factors (TFs). The binding patterns of the TFs to these sites, as well as the way the TFs interact with each other and with the RNA polymerase
Externí odkaz:
https://doaj.org/article/4c7f80a8322e415c8dc45d335c1210a1
Autor:
Gonzalo M. Sanchez, Liza Alkhori, Eduardo Hatano, Sebastian W. Schultz, Anujaianthi Kuzhandaivel, Shadi Jafari, Björn Granseth, Mattias Alenius
Publikováno v:
Cell Reports, Vol 14, Iss 3, Pp 464-470 (2016)
Hedgehog (Hh) signaling is a key regulatory pathway during development and also has a functional role in mature neurons. Here, we show that Hh signaling regulates the odor response in adult Drosophila olfactory sensory neurons (OSNs). We demonstrate
Externí odkaz:
https://doaj.org/article/e4e6bb1f785f4efcbd4deae39849de23
Publikováno v:
Pizhūhish va Nuāvarī dar ̒Ulūm va Sanāyi̒-i Ghaz̠āyī, Vol 3, Iss 1, Pp 51-66 (2014)
In this research, optimization of extraction process of green tea extract to maximize extracted solid yield and minimize turbidity of the samples was carried out using response surface methodology (RSM). The effects of two factors, extraction tempera
Externí odkaz:
https://doaj.org/article/d01b825c963340378a22b42134544419
Autor:
Shadi Jafari, Mattias Alenius
Publikováno v:
PLoS Genetics, Vol 11, Iss 3, p e1005051 (2015)
Odor perception requires that each olfactory sensory neuron (OSN) class continuously express a single odorant receptor (OR) regardless of changes in the environment. However, little is known about the control of the robust, class-specific OR expressi
Externí odkaz:
https://doaj.org/article/eab849f841ec439c8f1b57a49d512eac
Autor:
Shadi Jafari, Liza Alkhori, Alexander Schleiffer, Anna Brochtrup, Thomas Hummel, Mattias Alenius
Publikováno v:
PLoS Biology, Vol 10, Iss 3, p e1001280 (2012)
The mechanism that specifies olfactory sensory neurons to express only one odorant receptor (OR) from a large repertoire is critical for odor discrimination but poorly understood. Here, we describe the first comprehensive analysis of OR expression re
Externí odkaz:
https://doaj.org/article/3ffa988fd9f2410a8dff95a368c5c335
Publikováno v:
Annual Review of Neuroscience. 44:153-172
During the approximately 5 days of Drosophila neurogenesis (late embryogenesis to the beginning of pupation), a limited number of neural stem cells produce approximately 200,000 neurons comprising hundreds of cell types. To build a functional nervous
Autor:
Katarina Kapuralin, Yen Chung Chen, Rana N. El-Danaf, Shadi Jafari, Nikolaos Konstantinides, Najate Benhra, Mehmet Neset Özel, Jennifer Amy Malin, Isabel Holguera, Claude Desplan, Félix Simon
Publikováno v:
Nature
Deciphering how neuronal diversity is established and maintained requires a detailed knowledge of neuronal gene expression throughout development. In contrast to mammalian brains1,2, the large neuronal diversity of the Drosophila optic lobe3 and its
Publikováno v:
Journal of Diabetes Mellitus. :126-136
Diabetes mellitus is a chronic disease with a multitude of effects on different organ-systems. Its chronic nature makes it a challenging disease for patients to manage. Today, patients have access to many different types of conventional therapies for
Publikováno v:
Open Journal of Emergency Medicine. :41-47
Growing evidence has made it obvious that early intervention in patients with Achilles tendon rupture extensively affects the prognosis. This requires the use of easily accessible imaging modalities such as ultrasound in establishing accurate diagnos