A novel read methodology to evaluate the optimal dose of 68Ga-satoreotide trizoxetan as a PET imaging agent in patients with gastroenteropancreatic neuroendocrine tumours: a phase II clinical trial

Autor: Colin G. Miller, Henning Grønbæk, Irene Virgolini, Andreas Kjaer, Pierre Terve, Shadfar Bahri, Peter Iversen, Hanna Svirydenka, Thomas Rohban, Sandy McEwan

Publikováno v: EJNMMI Research, Vol 11, Iss 1, Pp 1-11 (2021)

Abstract Background 68Ga-satoreotide trizoxetan is a novel somatostatin receptor antagonist exhibiting higher tumour-to-background ratios and sensitivity compared to 68Ga-DOTATOC. This randomised, 2 × 3 factorial, phase II study aimed to confirm the

Externí odkaz: https://doaj.org/article/4c8b1bb0808c480fadaf97e8afe9d6a7

Head-to-Head Comparison of 68Ga-PSMA-11 PET/CT and mpMRI with a Histopathology Gold Standard in the Detection, Intraprostatic Localization, and Determination of Local Extension of Primary Prostate Cancer: Results from a Prospective Single-Center Imaging Trial

Autor: Staven S Raman, Ida Sonni, Ely Felker, Anthony Sisk, Wesley R Armstrong, Tristan Grogan, Jeremie Calais, Teeravut Tubtawee, Robert E. Reiter, Andrew T. Lenis, David Elashoff, Shadfar Bahri, Johannes Czernin, Matthias Eiber, Martin Allen-Auerbach, Voraparee Suvannarerg

Publikováno v: Journal of Nuclear Medicine. 63:847-854

The role of prostate-specific membrane antigen (PSMA)-targeted PET in comparison to mpMRI in the evaluation of intraprostatic cancer foci is not well defined. The aim of our study was to compare the diagnostic performances of PSMA PET/CT, mpMRI and P

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6a334e38294e8b6b5212e57516cf43bd
https://doi.org/10.2967/jnumed.121.262398

Worse prognosis for IDH wild-type diffuse gliomas with larger residual biological tumor burden

Autor: Albert Lai, Catalina Raymond, Benjamin M. Ellingson, Phioanh L. Nghiemphu, Linda M. Liau, Hiroyuki Uetani, Shadfar Bahri, Noriko Salamon, Akifumi Hagiwara, Timothy F. Cloughesy, Whitney B. Pope, Hiroyuki Tatekawa

Publikováno v: Annals of Nuclear Medicine. 35:1022-1029

The association of overall survival (OS) with tumor burden, including contrast enhanced (CE) volume on CE T1-weighted images, fluid-attenuated inversion recovery (FLAIR) hyperintense volume, and 3, 4-dihydroxy-6-[18F]-fluoro-L-phenylalanine (FDOPA) h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ae37ad9c6fa4fa43bcb47a7a10b1b7b4
https://doi.org/10.1007/s12149-021-01637-0

A Randomized, Factorial Phase II Study to Determine the Optimal Dosing Regimen for 68Ga-Satoreotide Trizoxetan as an Imaging Agent in Patients with Gastroenteropancreatic Neuroendocrine Tumors

Autor: Ulrich Knigge, Shadfar Bahri, Johannes Czernin, Peter Iversen, Andreas Kjaer, Esben Andreas Carlsen, Christine Powell, Johanna Maffey-Steffan, Henning Grønbæk, Irene Virgolini, Sandy McEwan, Colin G. Miller, Mathias Loft, Thomas Rohban

Publikováno v: Virgolini, I, Bahri, S, Kjaer, A, Gronbaek, H, Iversen, P, Carlsen, E A, Loft, M, Knigge, U, Maffey-Steffan, J, Powell, C, Miller, C G, Rohban, T, McEwan, S & Czernin, J 2022, ' A Randomized, Factorial Phase II Study to Determine the Optimal Dosing Regimen for 68 Ga-Satoreotide Trizoxetan as an Imaging Agent in Patients with Gastroenteropancreatic Neuroendocrine Tumors ', Journal of Nuclear Medicine, vol. 63, no. 3, pp. 376-383 . https://doi.org/10.2967/jnumed.121.261936
Virgolini, I, Bahri, S, Kjaer, A, Gronbaek, H, Iversen, P, Carlsen, E A, Loft, M, Knigge, U, Maffey-Steffan, J, Powell, C, Miller, C G, Rohban, T, McEwan, S & Czernin, J 2022, ' A randomised, factorial phase II study to determine the optimal dosing regimen for 68 Ga-satoreotide trizoxetan as an imaging agent in patients with gastroenteropancreatic neuroendocrine tumours ', Journal of nuclear medicine : official publication, Society of Nuclear Medicine, vol. 63, no. 3 . https://doi.org/10.2967/jnumed.121.261936

68Ga-satoreotide trizoxetan is a novel somatostatin receptor antagonist associated with high sensitivity and reproducibility in neuroendocrine tumour (NET) detection and localisation. However, the optimal peptide mass and radioactivity ranges for 68G

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f46b7d8b3fed34544124a81cf18e8ced
https://pure.au.dk/portal/da/publications/a-randomized-factorial-phase-ii-study-to-determine-the-optimal-dosing-regimen-for-68gasatoreotide-trizoxetan-as-an-imaging-agent-in-patients-with-gastroenteropancreatic-neuroendocrine-tumors(efd7ada3-d130-4069-aa7e-652d008e0f37).html

Calculation of the estimated glomerular filtration rate using the 2021 CKD-EPI creatinine equation and whole blood creatinine values measured with Radiometer ABL 827 FLEX

Autor: Lu Song, Vincent Buggs, Vishnu Amaram Samara, Shadfar Bahri

Publikováno v: Clinical chemistry and laboratory medicineReferences. 60(6)

Objectives Estimated glomerular filtration rate (eGFR) can be calculated using serum/plasma creatinine measured with automated chemistry analyzers. It is unclear whether eGFR can be calculated using creatinine values measured in whole blood (WB creat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::388b0f6740170804adc70918aa6b036d
https://pubmed.ncbi.nlm.nih.gov/35427449