Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Shadab A Rahman"'
Autor:
Shadab A. Rahman, Rose M. Gathungu, Vasant R. Marur, Melissa A. St. Hilaire, Karine Scheuermaier, Marina Belenky, Jackson S. Struble, Charles A. Czeisler, Steven W. Lockley, Elizabeth B. Klerman, Jeanne F. Duffy, Bruce S. Kristal
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-14 (2023)
Abstract Aging alters the amplitude and phase of centrally regulated circadian rhythms. Here we evaluate whether peripheral circadian rhythmicity in the plasma lipidome is altered by aging through retrospective lipidomics analysis on plasma samples c
Externí odkaz:
https://doaj.org/article/3742515d31644d57a70e020f49e8c67c
Autor:
Brianne A. Kent, Shadab A. Rahman, Melissa A. St. Hilaire, Leilah K. Grant, Melanie Rüger, Charles A. Czeisler, Steven W. Lockley
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-7 (2022)
A key property of circadian rhythms is that they can be reset in response to environmental time cues; this response is described by a Phase Response Curve (PRC). Here the authors describe PRCs for resetting circadian rhythms in lipids and hepatic pro
Externí odkaz:
https://doaj.org/article/27fa74429d6e4c85a872cc758c6f7862
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/4f5cf204b7684e4d9aa5aa694a91e295
Autor:
Leilah K. Grant, Brianne A. Kent, Matthew D. Mayer, Robert Stickgold, Steven W. Lockley, Shadab A. Rahman
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
We tested the effect of daytime indoor light exposure with varying melanopic strength on cognitive performance in college-aged students who maintained an enforced nightly sleep opportunity of 7 h (i.e., nightly sleep duration no longer than 7 h) for
Externí odkaz:
https://doaj.org/article/a3ff7b6ce5e8443eb0c8b99117b17f6b
Autor:
Brianne A. Kent, Shadab A. Rahman, Melissa A. St. Hilaire, Leilah K. Grant, Melanie Rüger, Charles A. Czeisler, Steven W. Lockley
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/f534c8fce57d45848542d2c5c57f91f7
Autor:
Bojana Gladanac, James Jonkman, Colin M. Shapiro, Theodore J. Brown, Martin R. Ralph, Robert F. Casper, Shadab A. Rahman
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Visible light is the principal stimulus for resetting the mammalian central circadian pacemaker. Circadian phase resetting is most sensitive to short-wavelength (blue) visible light. We examined the effects of removing short-wavelengths < 500 nm from
Externí odkaz:
https://doaj.org/article/81a9727a20894dd8966a04f1a285a476
Autor:
Aviva Y Cohn, Leilah K Grant, Margo D Nathan, Aleta Wiley, Mathena Abramson, Jessica A Harder, Sybil Crawford, Elizabeth B Klerman, Frank A J L Scheer, Ursula B Kaiser, Shadab A Rahman, Hadine Joffe
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism.
Context Perturbations to the hypothalamic-pituitary-adrenal (HPA) axis have been hypothesized to increase post-menopausal cardiometabolic risk. Although sleep disturbance, a known risk factor for cardiometabolic disease, is prevalent during the menop
Autor:
Shadab A Rahman, Erica L Mayer, Hanneke Poort, Deborah Schrag, Stephanie C Tung, Eric S Zhou, Aleta Wiley, Lauren Finkelstein, Elkhansaa Elguenaoui, Moira Nolan, Hadine Joffe
Publikováno v:
Cancer Research. 82:P4-09
Background: Clinician-rated adverse event data from pivotal trials of the CDK4/6 inhibitor palbociclib (palbo) in patients (pts) with HR+ HER2- metastatic breast cancer (MBC) describe fatigue as a common non-hematologic toxicity. While palbo and endo
Autor:
Melissa A. St Hilaire, María L. Ámundadóttir, Shadab A. Rahman, Shantha M. W. Rajaratnam, Melanie Rüger, George C. Brainard, Charles A. Czeisler, Marilyne Andersen, Joshua J. Gooley, Steven W. Lockley
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(51)
Human circadian, neuroendocrine, and neurobehavioral responses to light are mediated primarily by melanopsin-containing intrinsically-photosensitive retinal ganglion cells (ipRGCs) but they also receive input from visual photoreceptors. Relative phot
Autor:
Shadab A. Rahman, Brianne A. Kent, Leilah K. Grant, Toni Clark, John P. Hanifin, Laura K. Barger, Charles A. Czeisler, George C. Brainard, Melissa A St Hilaire, Steven W. Lockley
Publikováno v:
Journal of Pineal Research. 73
Spaceflight exposes crewmembers to circadian misalignment and sleep loss, which impair cognition and increase the risk of errors and accidents. We compared the effects of an experimental dynamic lighting schedule (DLS) with a standard static lighting