Effect of Human Genetic Variability on Gene Expression in Dorsal Root Ganglia and Association with Pain Phenotypes

Autor: Marc Parisien, Samar Khoury, Anne-Julie Chabot-Doré, Susana G. Sotocinal, Gary D. Slade, Shad B. Smith, Roger B. Fillingim, Richard Ohrbach, Joel D. Greenspan, William Maixner, Jeffrey S. Mogil, Inna Belfer, Luda Diatchenko

Publikováno v: Cell Reports, Vol 19, Iss 9, Pp 1940-1952 (2017)

Dorsal root ganglia (DRG) relay sensory information to the brain, giving rise to the perception of pain, disorders of which are prevalent and burdensome. Here, we mapped expression quantitative trait loci (eQTLs) in a collection of human DRGs. DRG eQ

Externí odkaz: https://doaj.org/article/3a6588954ecc4835a5e89cb2f02df82b

Carbonic anhydrase-8 regulates inflammatory pain by inhibiting the ITPR1-cytosolic free calcium pathway.

Autor: Gerald Z Zhuang, Benjamin Keeler, Jeff Grant, Laura Bianchi, Eugene S Fu, Yan Ping Zhang, Diana M Erasso, Jian-Guo Cui, Tim Wiltshire, Qiongzhen Li, Shuanglin Hao, Konstantinos D Sarantopoulos, Keith Candiotti, Sarah M Wishnek, Shad B Smith, William Maixner, Luda Diatchenko, Eden R Martin, Roy C Levitt

Publikováno v: PLoS ONE, Vol 10, Iss 3, p e0118273 (2015)

Calcium dysregulation is causally linked with various forms of neuropathology including seizure disorders, multiple sclerosis, Huntington's disease, Alzheimer's, spinal cerebellar ataxia (SCA) and chronic pain. Carbonic anhydrase-8 (Car8) is an allos

Externí odkaz: https://doaj.org/article/f006429f8d464daaab0bce01e3df7098

Applying the Rapid OPPERA Algorithm to Predict Persistent Pain Outcomes Among a Cohort of Women Undergoing Breast Cancer Surgery

Autor: Wilson, Jenna M. ^*, Colebaugh, Carin A. ^*, Flowers, K. Mikayla ^*, Overstreet, Demario ^*, Edwards, Robert R. ^*, Maixner, William, Smith, Shad B., Schreiber, Kristin L. ^*

Publikováno v: In The Journal of Pain December 2022 23(12):2003-2012

Disentangling the genetics of lean mass

Autor: Karasik, David, Zillikens, M Carola, Hsu, Yi-Hsiang, Aghdassi, Ali, Akesson, Kristina, Amin, Najaf, Barroso, Inês, Bennett, David A, Bertram, Lars, Bochud, Murielle, Borecki, Ingrid B, Broer, Linda, Buchman, Aron S, Byberg, Liisa, Campbell, Harry, Campos-Obando, Natalia, Cauley, Jane A, Cawthon, Peggy M, Chambers, John C, Chen, Zhao, Cho, Nam H, Choi, Hyung Jin, Chou, Wen-Chi, Cummings, Steven R, de Groot, Lisette C P G M, De Jager, Phillip L, Demuth, Ilja, Diatchenko, Luda, Econs, Michael J, Eiriksdottir, Gudny, Enneman, Anke W, Eriksson, Joel, Eriksson, Johan G, Estrada, Karol, Evans, Daniel S, Feitosa, Mary F, Fu, Mao, Gieger, Christian, Grallert, Harald, Gudnason, Vilmundur, Lenore, Launer J, Hayward, Caroline, Hofman, Albert, Homuth, Georg, Huffman, Kim M, Husted, Lise B, Illig, Thomas, Ingelsson, Erik, Ittermann, Till, Jansson, John-Olov, Johnson, Toby, Biffar, Reiner, Jordan, Joanne M, Jula, Antti, Karlsson, Magnus, Khaw, Kay-Tee, Kilpeläinen, Tuomas O, Klopp, Norman, Kloth, Jacqueline S L, Koller, Daniel L, Kooner, Jaspal S, Kraus, William E, Kritchevsky, Stephen, Kutalik, Zoltán, Kuulasmaa, Teemu, Kuusisto, Johanna, Laakso, Markku, Lahti, Jari, Lang, Thomas, Langdahl, Bente L, Lerch, Markus M, Lewis, Joshua R, Lill, Christina, Lind, Lars, Lindgren, Cecilia, Liu, Yongmei, Livshits, Gregory, Ljunggren, Östen, Loos, Ruth J F, Lorentzon, Mattias, Luan, Jian'an, Luben, Robert N, Malkin, Ida, McGuigan, Fiona E, Medina-Gomez, Carolina, Meitinger, Thomas, Melhus, Håkan, Mellström, Dan, Michaëlsson, Karl, Mitchell, Braxton D, Morris, Andrew P, Mosekilde, Leif, Nethander, Maria, Newman, Anne B, O'Connell, Jeffery R, Oostra, Ben A, Orwoll, Eric S, Palotie, Aarno, Peacock, Munro, Perola, Markus, Peters, Annette, Prince, Richard L, Psaty, Bruce M, Räikkönen, Katri, Ralston, Stuart H, Ripatti, Samuli, Rivadeneira, Fernando, Robbins, John A, Rotter, Jerome I, Rudan, Igor, Salomaa, Veikko, Satterfield, Suzanne, Schipf, Sabine, Shin, Chan Soo, Smith, Albert V, Smith, Shad B, Soranzo, Nicole, Spector, Timothy D, Stančáková, Alena, Stefansson, Kari, Steinhagen-Thiessen, Elisabeth, Stolk, Lisette, Streeten, Elizabeth A, Styrkarsdottir, Unnur, Swart, Karin M A, Thompson, Patricia, Thomson, Cynthia A, Thorleifsson, Gudmar, Thorsteinsdottir, Unnur, Tikkanen, Emmi, Tranah, Gregory J, Uitterlinden, André G, van Duijn, Cornelia M, van Schoor, Natasja M, Vandenput, Liesbeth, Vollenweider, Peter, Völzke, Henry, Wactawski-Wende, Jean, Walker, Mark, J Wareham, Nicholas, Waterworth, Dawn, Weedon, Michael N, Wichmann, H-Erich, Widen, Elisabeth, Williams, Frances M K, Wilson, James F, Wright, Nicole C, Yerges-Armstrong, Laura M, Yu, Lei, Zhang, Weihua, Zhao, Jing Hua, Zhou, Yanhua, Nielson, Carrie M, Harris, Tamara B, Demissie, Serkalem, Kiel, Douglas P, Ohlsson, Claes

Publikováno v: In The American Journal of Clinical Nutrition February 2019 109(2):276-287

Social Modulation of Pain as Evidence for Empathy in Mice

Autor: Langford, Dale J., Crager, Sara E., Shehzad, Zarrar, Smith, Shad B., Sotocinal, Susana G., Levenstadt, Jeremy S., Chanda, Mona Lisa, Levitin, Daniel J., Mogil, Jeffrey S.

Publikováno v: Science, 2006 Jun . 312(5782), 1967-1970.

Externí odkaz: https://www.jstor.org/stable/3846447