WNT4 Regulates Cellular Metabolism via Intracellular Activity at the Mitochondria in Breast and Gynecologic Cancers.

Autor: Sottnik JL; Department of Pathology, University of Colorado Anschutz Medical Campus, Aurora, Colorado., Shackleford MT; Department of Pathology, University of Colorado Anschutz Medical Campus, Aurora, Colorado., Robinson SK; Department of Pathology, University of Colorado Anschutz Medical Campus, Aurora, Colorado., Villagomez FR; Division of Reproductive Sciences, Department of Obstetrics and Gynecology, University of Colorado Anschutz Medical Campus, Aurora, Colorado., Bahnassy S; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, District of Columbia., Oesterreich S; Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, Pennsylvania., Hu J; Biostatistics and Bioinformatics Shared Resource, University of Colorado Cancer Center, Aurora, Colorado., Madak-Erdogan Z; Department of Food Science and Human Nutrition, Cancer Center at Illinois, Division of Nutritional Sciences, University of Illinois Urbana-Champaign, Champaign, Illinois., Riggins RB; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, District of Columbia., Corr BR; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Colorado Anschutz Medical Campus, Aurora, Colorado., Cook LS; Department of Epidemiology, University of Colorado School of Public Health, Aurora, Colorado., Treviño LS; Depratment of Population Sciences, Division of Health Equities, City of Hope, Duarte, California., Bitler BG; Division of Reproductive Sciences, Department of Obstetrics and Gynecology, University of Colorado Anschutz Medical Campus, Aurora, Colorado., Sikora MJ; Department of Pathology, University of Colorado Anschutz Medical Campus, Aurora, Colorado.

Publikováno v: Cancer research communications [Cancer Res Commun] 2024 Jan 17; Vol. 4 (1), pp. 134-151.

Wnt family member 4 (WNT4) and WNT3A activate cell-autonomous Wnt signaling independent of porcupine O- acyltransferase or Wnt secretion.

Autor: Rao DM; Department of Pathology, University of Colorado Anschutz Medical Campus, Aurora, Colorado 80045., Shackleford MT; Department of Pathology, University of Colorado Anschutz Medical Campus, Aurora, Colorado 80045., Bordeaux EK; Department of Pathology, University of Colorado Anschutz Medical Campus, Aurora, Colorado 80045., Sottnik JL; Department of Pathology, University of Colorado Anschutz Medical Campus, Aurora, Colorado 80045., Ferguson RL; Department of Pathology, University of Colorado Anschutz Medical Campus, Aurora, Colorado 80045., Yamamoto TM; Department of Obstetrics and Gynecology, University of Colorado Anschutz Medical Campus, Aurora, Colorado 80045., Wellberg EA; Department of Pathology, University of Colorado Anschutz Medical Campus, Aurora, Colorado 80045., Bitler BG; Department of Obstetrics and Gynecology, University of Colorado Anschutz Medical Campus, Aurora, Colorado 80045., Sikora MJ; Department of Pathology, University of Colorado Anschutz Medical Campus, Aurora, Colorado 80045 matthew.sikora@cuanschutz.edu.

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2019 Dec 27; Vol. 294 (52), pp. 19950-19966. Date of Electronic Publication: 2019 Nov 18.