Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Shachi J. Sharma"'
Autor:
Philipp H. Zimmermann, Marijn Stuut, Nora Wuerdemann, Kathrin Möllenhoff, Malte Suchan, Hans Eckel, Philipp Wolber, Shachi J. Sharma, Fabian Kämmerer, Christine Langer, Claus Wittekindt, Steffen Wagner, Bernd Kremer, Ernst Jan M. Speel, Jens P. Klussmann
Publikováno v:
Cancers, Vol 13, Iss 21, p 5265 (2021)
The two pillars of therapy for oropharyngeal squamous cell carcinoma (OPSCC) are upfront surgery and primary chemoradiotherapy. Substantial regional preferences exist with regard to the selection of treatment. Despite new therapeutic approaches, pati
Externí odkaz:
https://doaj.org/article/5ae0a5200d4941c6b90f40fb163a3e2c
Autor:
Nora Wuerdemann, Katharina Pütz, Hans Eckel, Rishabh Jain, Claus Wittekindt, Christian U. Huebbers, Shachi J. Sharma, Christine Langer, Stefan Gattenlöhner, Reinhard Büttner, Ernst-Jan Speel, Malte Suchan, Steffen Wagner, Alexander Quaas, Jens P. Klussmann
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 1, p 379 (2020)
Tumor growth and survival requires a particularly effective immunosuppressant tumor microenvironment (TME) to escape destruction by the immune system. While immunosuppressive checkpoint markers like programmed cell death 1 ligand (PD-L1) are already
Externí odkaz:
https://doaj.org/article/5629dd4a34ac4603bb5a863ee45fa51f
Autor:
Nora Wuerdemann, Sibel E. Gültekin, Katharina Pütz, Claus Wittekindt, Christian U. Huebbers, Shachi J. Sharma, Hans Eckel, Anna B. Schubotz, Stefan Gattenlöhner, Reinhard Büttner, Ernst-Jan Speel, Jens P. Klussmann, Steffen Wagner, Alexander Quaas
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 15, p 5228 (2020)
Carcinogenesis of human papillomavirus (HPV)-related (+) oropharyngeal squamous cell carcinoma (OPSCC) differs from HPV-negative (–) OPSCC. HPV-related immune-escape-mechanism could be responsible for the development and progression of HPV+ tumors
Externí odkaz:
https://doaj.org/article/a9c7f67aba144c01adecdb69058cd60e
Autor:
Jennifer, Knuth, Shachi J, Sharma, Nora, Würdemann, Claudia, Holler, Boyan K, Garvalov, Till, Acker, Claus, Wittekindt, Steffen, Wagner, Jens P, Klussmann
Publikováno v:
Oncotarget
Purpose Human papillomavirus (HPV) is a causative agent for a rising number of head and neck squamous cell carcinomas (HNSCC), which are characterized by distinct tumor biology. Hypoxia inducible-factor (HIF) signaling influences initiation and progr