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pro vyhledávání: '"Shabtai, Varsano"'
Publikováno v:
The Journal of asthma : official journal of the Association for the Care of Asthma. 58(8)
Controlled severe asthma is based on needing regular medication and 4 markers of good asthma control. This study reevaluated a community sample defined 4 years earlier as "severe-controlled" based on electronic medical records of medications dispense
Publikováno v:
Respiratory medicine. 123
Background A large electronic database analysis was conducted in a community of 351,799 people, ages 20–70 years to determine the prevalence and clinical characteristics of severe asthma, according to 2014 international guidelines and healthcare ut
Publikováno v:
Thorax. 55:364-369
BACKGROUND—The interrelationship between human airway epithelium and complement proteins may affect airway defence, airway function, and airway epithelial integrity. A study was undertaken to determine (1) whether unstimulated human bronchial epith
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 19:522-529
Human lung cancers overexpress several cell-membrane complement inhibitory proteins (CIP). These complement inhibitory proteins are membrane cofactor protein (CD46), decay-accelerating factor (DAF; CD55), and CD59 (protectin). These cell-membrane pro
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 15:731-737
Complement in the respiratory tract protects the host from invading micoorganisms and other inhaled insults, but may damage normal tissue. Recently we reported that human respiratory epithelium from the nose to the alveoli expresses three cell-membra
Autor:
Shabtai, Varsano
Publikováno v:
Harefuah. 151(4)
Five to ten percent of all asthmatics, many dozens of millions of patients all over the world, do not respond to maximal medical therapy, including systemic steroids, and the toll of treating them constitutes about eighty percent of the total cost of
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 10:298-305
Airway inflammation is characterized by intraluminal influx of inflammatory cells, exudation of plasma, and increased procoagulant activity. We speculated that inflammatory cells might adhere to the airway surface epithelium in order to better locali
Publikováno v:
Harefuah. 150(1)
Patent foramen ovate is a common finding in the general population. However, interatrial right to left shunt causing severe hypoxemia in the absence of pulmonary hypertension is a rare finding. The authors describe two such patients suffering from se
Autor:
Shabtai, Varsano, Yehoshua, Smorzik
Publikováno v:
The Israel Medical Association journal : IMAJ. 10(10)
Autor:
Shabtai, Varsano
Publikováno v:
Harefuah. 146(4)
Asthma is a common chronic disease worldwide, affecting 300 million people of all ages. In spite of the existence of scientifically proven clinical guidelines for the past 15 years and efficient controller medications, the gaps between asthma managem