Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Shabnam Hemmati-Sadeghi"'
Publikováno v:
Journal of Materials Science: Materials in Medicine, Vol 35, Iss 1, Pp 1-15 (2024)
Abstract Tissue engineering holds promise for developing therapeutic applications using viscous materials e.g. hydrogels. However, assessing the cytotoxicity of such materials with conventional assays can be challenging due to non-specific interactio
Externí odkaz:
https://doaj.org/article/36d45c40499c43a3b132f2b9123f9dc1
Autor:
Jacob Spinnen, Lennard K. Shopperly, Carsten Rendenbach, Anja A. Kühl, Ufuk Sentürk, Daniel Kendoff, Shabnam Hemmati-Sadeghi, Michael Sittinger, Tilo Dehne
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 12, p 6394 (2021)
For in vitro modeling of human joints, osteochondral explants represent an acceptable compromise between conventional cell culture and animal models. However, the scarcity of native human joint tissue poses a challenge for experiments requiring high
Externí odkaz:
https://doaj.org/article/a7f592088a9546bfac8ed9fa87043d10
Autor:
Laura Stahn, Justyna Rasińska, Tilo Dehne, Stefanie Schreyer, Aileen Hakus, Manfred Gossen, Barbara Steiner, Shabnam Hemmati-Sadeghi
Publikováno v:
Stahn, L.; Rasińska, J.; Dehne, T.; Schreyer, S.; Hakus, A.; Gossen, M.; Steiner, B.; Hemmati-Sadeghi, S.: Sleeping beauty transposon system for GDNF overexpression of entrapped stem cells in fibrin hydrogel in a rat model of Parkinson’s disease. In: Drug Delivery and Translational Research. Vol. 13 (2023) 1745-1765. (DOI: /10.1007/s13346-023-01289-9)
There is currently no causal treatment available for Parkinson’s disease (PD). However, the use of glial cell line–derived neurotrophic factor (GDNF) to provide regenerative effects for neurons is promising. Such approaches require translational
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8db912b583701e252dda57a53fa36115
https://publications.hereon.de/id/51317
https://publications.hereon.de/id/51317
Publikováno v:
Journal of Cell and Molecular Research, Vol 5, Iss 2, Pp 87-91 (2013)
Skin grafting always has been considered a challenging task for the researchers and tissue engineers from its first introduction in 1871 by Reverdin. Skin substitutes, composed of degradable synthetic or biological components, are being considered as
Externí odkaz:
https://doaj.org/article/ed9c2744b4164a1a9181a86683d5c31e
Autor:
Justyna Rasińska, Charlotte Klein, Laura Stahn, Felix Maidhof, Anna Pfeffer, Stefanie Schreyer, Manfred Gossen, Andreas Kurtz, Barbara Steiner, Shabnam Hemmati‐Sadeghi
Publikováno v:
Rasińska, J.; Klein, C.; Stahn, L.; Maidhof, F.; Pfeffer, A.; Schreyer, S.; Gossen, M.; Kurtz, A.; Steiner, B.; Hemmati-Sadeghi, S.: Transposon-mediated glial cell line-derived neurotrophic factor overexpression in human adipose tissue-derived mesenchymal stromal cells: A potential approach for neuroregenerative medicine?. In: Journal of Tissue Engineering and Regenerative Medicine. Vol. 16 (2022) 6, 515-529. (DOI: /10.1002/term.3296)
Glial cell line-derived neurotrophic factor (GDNF) has neuroprotective effects and may be a promising candidate for regenerative strategies focusing on neurodegenerative diseases. As GDNF cannot cross the blood–brain barrier to potentially regenera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1b632b30fa4826a868091ffa27cd375
https://pubmed.ncbi.nlm.nih.gov/35278347
https://pubmed.ncbi.nlm.nih.gov/35278347
Autor:
Anja E. Hauser, Georg N. Duda, Paula Hoff, Jonathan Stefanowski, Annemarie Lang, Max Löhning, Alexandra Damerau, Shabnam Hemmati-Sadeghi, Angelique Wolter, Timo Gaber, Frank Buttgereit, Moritz Pfeiffenberger, Rainer Haag, Katharina Schmidt-Bleek
Publikováno v:
Bone. 154
The initial phase of fracture healing is crucial for the success of bone regeneration and is characterized by an inflammatory milieu and low oxygen tension (hypoxia). Negative interference with or prolongation of this fine-tuned initiation phase will
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45415844e8eee4ed864c4a1aacc910f0
https://pubmed.ncbi.nlm.nih.gov/34743042
https://pubmed.ncbi.nlm.nih.gov/34743042
Autor:
Jochen Ringe, Michael Sittinger, Shabnam Hemmati-Sadeghi, Andreas Engels, Kristin Fröhlich, Tilo Dehne, Katja Reiter
Publikováno v:
Journal of Orthopaedic Research. 37:1723-1729
There is evidence that the application of mesenchymal stromal cells (MSCs) counteracts osteoarthritis (OA) progression. However, the prospect of extracting and expanding these cells might be limited. The aim of this study was to investigate whether h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c445fce42cea66516997391feb58e3a
https://doi.org/10.1002/jor.24312
https://doi.org/10.1002/jor.24312
Autor:
Katharina Schmidt-Bleek, A. Kuppe, Rainer Haag, Georg N. Duda, Annemarie Lang, M. Loehning, Moritz Pfeiffenberger, Vikram Sunkara, Angelique Wolter, Timo Gaber, Anja E. Hauser, S. Helfmeier, Alexandra Damerau, Shabnam Hemmati-Sadeghi, Carsten Perka, Jochen Ringe, Jonathan Stefanowski, Frank Buttgereit, Paula Hoff
The initial phase of fracture healing decides on success of bone regeneration and is characterized by an inflammatory milieu and low oxygen tension (hypoxia). Negative interference with or prolongation of this fine-tuned initiation phase will ultimat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b2e8187d7943294744fbc714b368bf9
https://doi.org/10.1101/2020.07.02.182832
https://doi.org/10.1101/2020.07.02.182832
Autor:
Stefanie Schreyer, Charlotte Klein, Anna Pfeffer, Justyna Rasińska, Laura Stahn, Karlotta Knuth, Basim Abuelnor, Alina Elisabeth Catharina Panzel, André Rex, Stefan Koch, Shabnam Hemmati-Sadeghi, Barbara Steiner
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Glucose hypometabolism potentially contributes to Alzheimer’s disease (AD) and might even represent an underlying mechanism. Here, we investigate the relationship of diet-induced metabolic stress and AD as well as the therapeutic potential of chia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bb9f5b748f3b8318acde04ae3839617
https://doi.org/10.1038/s41598-020-75209-z
https://doi.org/10.1038/s41598-020-75209-z
Autor:
Jochen Ringe, Shabnam Hemmati-Sadeghi, Tilo Dehne, Pradip Dey, Rainer Haag, Michael Sittinger
Publikováno v:
Journal of Biomedical Materials Research Part B: Applied Biomaterials. 107:490-500
This study aimed to evaluate the potential of an anti-inflammatory polyethylene glycol (PEG) hydrogel for osteoarthritis (OA) management in an OA in vitro model. Freshly isolated porcine chondrocytes were maintained in high-density cultures to form c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5fc2ffc692a65986aa77b0a52b172d62
https://doi.org/10.1002/jbm.b.34139
https://doi.org/10.1002/jbm.b.34139