Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Shab Masih"'
Autor:
Gail Lewis Phillips, Guangmin Li, Jun Guo, Shang-Fan Yu, Genee Lee, Donglu Zhang, Peter Dragovich, Thomas Pillow, Binqing Wei, M. Violet Lee, Ola Saad, Shab Masih, Douglas Leipold, Lisa Crocker, Melissa Schutten
Publikováno v:
Cancer Research. 82:P2-13
Background: Many HER2-directed antibody-drug conjugates (ADCs) in early development employ trastuzumab linked to tubulin binding agents as the cytotoxic drug. DHES0815A is an ADC consisting of a THIOMABTM humanized IgG1 anti-HER2 monoclonal antibody
Autor:
Ben-Quan Shen, Shab Masih, Brandon Latifi, Isabel Figueroa, Carl Ng, Doug Leipold, Victor Yip, Amrita V. Kamath
Publikováno v:
Drug Metabolism and Disposition. 48:1247-1256
Anti-Ly6E-seco-cyclopropabenzindol-4-one dimer antibody-drug conjugate (ADC) has been reported to form an adduct with α1-microglobulin (A1M) in animal plasma, but with unknown impact on ADC PK and tissue distribution. In this study, we compared the
Autor:
Victor, Yip, Isabel, Figueroa, Brandon, Latifi, Shab, Masih, Carl, Ng, Doug, Leipold, Amrita, Kamath, Ben-Quan, Shen
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 48(12)
Anti-Ly6E