Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Shaan, Khurshid"'
Autor:
Sarah M. Urbut, Ming Wai Yeung, Shaan Khurshid, So Mi Jemma Cho, Art Schuermans, Jakob German, Kodi Taraszka, Kaavya Paruchuri, Akl C. Fahed, Patrick T. Ellinor, Ludovic Trinquart, Giovanni Parmigiani, Alexander Gusev, Pradeep Natarajan
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Coronary artery disease (CAD) is the leading cause of death among adults worldwide. Accurate risk stratification can support optimal lifetime prevention. Current methods lack the ability to incorporate new information throughout the life cou
Externí odkaz:
https://doaj.org/article/dbb0e85692d248568e99606b71073f1e
Autor:
James P. Pirruccello, Paolo Di Achille, Seung Hoan Choi, Joel T. Rämö, Shaan Khurshid, Mahan Nekoui, Sean J. Jurgens, Victor Nauffal, Shinwan Kany, FinnGen, Kenney Ng, Samuel F. Friedman, Puneet Batra, Kathryn L. Lunetta, Aarno Palotie, Anthony A. Philippakis, Jennifer E. Ho, Steven A. Lubitz, Patrick T. Ellinor
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Increased left atrial volume and decreased left atrial function have long been associated with atrial fibrillation. The availability of large-scale cardiac magnetic resonance imaging data paired with genetic data provides a unique opportunit
Externí odkaz:
https://doaj.org/article/28dcb362d1d747399f72a9d9686b4b32
Autor:
Rachael A. Venn, Shaan Khurshid, Mia Grayson, Jeffrey M. Ashburner, Mostafa A. Al‐Alusi, Yuchiao Chang, Andrea Foulkes, Patrick T. Ellinor, David D. McManus, Daniel E. Singer, Steven J. Atlas, Steven A. Lubitz
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 1 (2024)
Background Consumer wearable devices with health and wellness features are increasingly common and may enhance disease detection and management. Yet studies informing relationships between wearable device use, attitudes toward device data, and compre
Externí odkaz:
https://doaj.org/article/e0a1fc4fb94842e3a1659dba67069f3c
Autor:
Adityanarayanan Radhakrishnan, Sam F. Friedman, Shaan Khurshid, Kenney Ng, Puneet Batra, Steven A. Lubitz, Anthony A. Philippakis, Caroline Uhler
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract A fundamental challenge in diagnostics is integrating multiple modalities to develop a joint characterization of physiological state. Using the heart as a model system, we develop a cross-modal autoencoder framework for integrating distinct
Externí odkaz:
https://doaj.org/article/b40d79696a384ecd99367367a11a9949
Autor:
Shaan Khurshid, Julieta Lazarte, James P. Pirruccello, Lu-Chen Weng, Seung Hoan Choi, Amelia W. Hall, Xin Wang, Samuel F. Friedman, Victor Nauffal, Kiran J. Biddinger, Krishna G. Aragam, Puneet Batra, Jennifer E. Ho, Anthony A. Philippakis, Patrick T. Ellinor, Steven A. Lubitz
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
A genome-wide association study of cardiac magnetic resonance-derived left ventricular mass index including 43,000 UK Biobank participants reveals 12 associations (11 novel), implicating genes involved in cardiac contractility and cardiomyopathy.
Externí odkaz:
https://doaj.org/article/1a8e275a72c04f6d9ede2ed763e2d9bc
Autor:
Shaan Khurshid, Lu-Chen Weng, Victor Nauffal, James P. Pirruccello, Rachael A. Venn, Mostafa A. Al-Alusi, Emelia J. Benjamin, Patrick T. Ellinor, Steven A. Lubitz
Publikováno v:
npj Digital Medicine, Vol 5, Iss 1, Pp 1-10 (2022)
Abstract Physical activity is regarded as favorable to health but effects across the spectrum of human disease are poorly quantified. In contrast to self-reported measures, wearable accelerometers can provide more precise and reproducible activity qu
Externí odkaz:
https://doaj.org/article/43708d4228014988804ccb8c78b39aff
Autor:
Jennifer L. Halford, Valerie N. Morrill, Seung Hoan Choi, Sean J. Jurgens, Giorgio Melloni, Nicholas A. Marston, Lu-Chen Weng, Victor Nauffal, Amelia W. Hall, Sophia Gunn, Christina A. Austin-Tse, James P. Pirruccello, Shaan Khurshid, Heidi L. Rehm, Emelia J. Benjamin, Eric Boerwinkle, Jennifer A. Brody, Adolfo Correa, Brandon K. Fornwalt, Namrata Gupta, Christopher M. Haggerty, Stephanie Harris, Susan R. Heckbert, Charles C. Hong, Charles Kooperberg, Henry J. Lin, Ruth J. F. Loos, Braxton D. Mitchell, Alanna C. Morrison, Wendy Post, Bruce M. Psaty, Susan Redline, Kenneth M. Rice, Stephen S. Rich, Jerome I. Rotter, Peter F. Schnatz, Elsayed Z. Soliman, Nona Sotoodehnia, Eugene K. Wong, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Marc S. Sabatine, Christian T. Ruff, Kathryn L. Lunetta, Patrick T. Ellinor, Steven A. Lubitz
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Accurate classification of genetic variants is critical for research and patient care. Here, the authors report that population-based associations between rare variants and quantitative endophenotypes for monogenic diseases can provide support for va
Externí odkaz:
https://doaj.org/article/816988c3c3b240bbb3a8c919e46440d7
Autor:
Napasri Chaisinanunkul, Shaan Khurshid, Brian H. Buck, Alejandro A. Rabinstein, Christopher D. Anderson, Michael D. Hill, Jennifer E. Fugate, Jeffrey L. Saver
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/f68f1ed809de4f60bce9e5694e274835
Autor:
Uri Kartoun, Shaan Khurshid, Bum Chul Kwon, Aniruddh P. Patel, Puneet Batra, Anthony Philippakis, Amit V. Khera, Patrick T. Ellinor, Steven A. Lubitz, Kenney Ng
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Prediction models are commonly used to estimate risk for cardiovascular diseases, to inform diagnosis and management. However, performance may vary substantially across relevant subgroups of the population. Here we investigated heterogeneity
Externí odkaz:
https://doaj.org/article/da4c4b26540e493baa092647a3b95bde
How often is occult atrial fibrillation in cryptogenic stroke causal vs. incidental? A meta-analysis
Autor:
Napasri Chaisinanunkul, Shaan Khurshid, Brian H. Buck, Alejandro A. Rabinstein, Christopher D. Anderson, Michael D. Hill, Jennifer E. Fugate, Jeffrey L. Saver
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
IntroductionLong-term cardiac monitoring studies have unveiled low-burden, occult atrial fibrillation (AF) in some patients with otherwise cryptogenic stroke (CS), but occult AF is also found in some individuals without a stroke history and in patien
Externí odkaz:
https://doaj.org/article/16b36cf069b44b04ac823ff4c80b5b52